18 Questions
What is the primary inhibitory neurotransmitter in the brain?
GABA
Which type of seizures does Phenytoin worsen?
Absence seizures
What is the main mechanism of action of Phenytoin?
Inhibits sodium channels
Which adverse effect is associated with Phenytoin use?
Gingival hyperplasia
What is the mechanism of action of Valproic Acid (Depakene®)?
Increases GABA levels
Which adverse effect is rare but serious in patients taking Valproic Acid (Depakene®)?
Liver toxicity
What is the therapeutic consideration related to drug withdrawal in epilepsy treatment?
Gradually taper off the drug to prevent increased risk of seizures
What is a potential adverse effect of Oxcarbazepine (Trileptal®) on the skin?
Rash
What is the function of a focus in initiating seizures?
Initiates synchronous, high-frequency discharge
How does Oxcarbazepine (Trileptal®) affect plasma sodium levels?
Decreases plasma sodium levels
Which drug interaction is common with Valproic Acid (Depakene®)?
Increased plasma levels of phenytoin
What is a potential consequence of teratogenicity related to Valproic Acid (Depakene®)?
Heart defects in the fetus
Which anticonvulsant drug is specifically used for absence seizures only?
Ethosuximide
Which newer anticonvulsant drug is used to treat neuropathic pain, migraine, and fibromyalgia?
Gabapentin
Which traditional anticonvulsant drug is used for trigeminal neuralgia?
Carbamazepine
Which newer anticonvulsant drug is used for weight loss and binge-eating?
Topiramate
Which benzodiazepines are used intravenously for status epilepticus?
Diazepam and lorazepam
'Newer' anticonvulsants are characterized by which of the following?
Broader therapeutic uses
Test your knowledge on Antiepileptic Drugs, Seizure Types, and related concepts. Explore how medications are used to manage excessive excitability of neurons in the CNS and the different types of seizures that can occur. Perfect for students or professionals in the medical field.
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