Antidepressants Overview
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Questions and Answers

What is a notable skin manifestation associated with barbiturate use?

  • Itching and swelling
  • Dry skin and peeling
  • Blisters over pressure points (correct)
  • Red rashes all over the body
  • Diminished bowel sounds are a gastrointestinal manifestation connected to barbiturates.

    True

    Name the symptom associated with barbiturates that affects body temperature.

    hypothermia

    Blisters over pressure points are referred to as __________.

    <p>bullae</p> Signup and view all the answers

    Match the following features with barbiturate manifestations:

    <p>Hypothermia = A body temperature drop Bullae formation = Blisters on skin Diminished bowel sounds = Reduced intestinal activity</p> Signup and view all the answers

    Which of the following is NOT a therapeutic use of tricyclic antidepressants?

    <p>Anxiety disorders</p> Signup and view all the answers

    Selective serotonin reuptake inhibitors (SSRIs) are classified as tricyclic antidepressants.

    <p>False</p> Signup and view all the answers

    What is one therapeutic use of tricyclic antidepressants?

    <p>Depression</p> Signup and view all the answers

    Tricyclic antidepressants can be used for the treatment of ______.

    <p>nocturnal enuresis</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>Lithium = A mood stabilizer used primarily to treat bipolar disorder SSRI = A class of antidepressants that selectively inhibit serotonin reuptake Tricyclic Antidepressants = A class of antidepressants that includes a cyclic structure Prophylaxis of Migraine = Preventive treatment to reduce the frequency of migraine attacks</p> Signup and view all the answers

    Which of the following is a common finding in hyperglycemia?

    <p>Suppression of insulin release from the pancreas</p> Signup and view all the answers

    Hypokalemia refers to a low level of potassium in the blood.

    <p>True</p> Signup and view all the answers

    What is one common cause of hypokalemia due to chronic toxicity?

    <p>Loop diuretics usage</p> Signup and view all the answers

    What is lactic acidosis?

    <p>A condition characterized by an increase in lactic acid in the body, often leading to acid-base imbalances.</p> Signup and view all the answers

    The first step in the treatment of hyperglycemia is __________ measures.

    <p>ABCs</p> Signup and view all the answers

    Chronic diarrhea can contribute to hypokalemia.

    <p>True</p> Signup and view all the answers

    Name one investigation that can help diagnose hypokalemia.

    <p>Serum potassium level test</p> Signup and view all the answers

    Match the following conditions with their effects:

    <p>Hyperglycemia = Suppression of insulin Hypokalemia = Low potassium levels Lactic acidosis = Increased lactic acid Hyperkalemia = High potassium levels</p> Signup and view all the answers

    Hypokalemia can result from poor dietary __________.

    <p>intake</p> Signup and view all the answers

    Match the conditions with their relevance to hypokalemia:

    <p>Loop diuretics = Can cause potassium loss Diarrhea = Leads to electrolyte imbalance Poor dietary intake = Contributes to deficiency Chronic toxicity = Results from prolonged exposure</p> Signup and view all the answers

    Which condition is associated with severe refractory shock?

    <p>Severe hypotension</p> Signup and view all the answers

    Pulmonary edema is a respiratory condition associated with cough and dyspnea.

    <p>True</p> Signup and view all the answers

    What type of liver damage is indicated by centrilobular necrosis?

    <p>Hepatic injury</p> Signup and view all the answers

    Severe hypotension can be a sign of ______ shock.

    <p>refractory</p> Signup and view all the answers

    Match the following medical conditions with their health system:

    <p>Severe refractory shock = Cardiac Pulmonary edema = Respiratory Centrilobular necrosis = Hepatic Metabolic acidosis = Metabolic</p> Signup and view all the answers

    Study Notes

    Antidepressants Overview

    • Lithium: Used as a mood stabilizer, particularly in bipolar disorder.
    • SSRIs: New class of antidepressants, effective for depression and anxiety disorders.

    Tricyclic Antidepressants (TCAs)

    • Therapeutic Uses:

      • Treats depression and panic disorders.
      • Used for nocturnal enuresis (bedwetting) in children.
      • Prophylaxis for migraines.
    • Skin Manifestations:

      • Can cause blisters (bullae) over pressure points, particularly on hands and feet.
    • Gastrointestinal Issues:

      • Notable for diminished bowel sounds, indicating reduced intestinal activity.

    Distinguishing Features

    • Comparison to Barbiturates:

      • Barbiturate poisoning may lead to hypothermia and bullae formation, distinct from TCAs.
    • Common Lab Findings:

      • Hyperglycemia is common due to insulin release suppression from the pancreas.
      • Electrolyte imbalances may occur, including hypokalemia or hyperkalemia.
      • Lactic acidosis may develop.

    Treatment Protocols

    • Immediate Interventions:

      • Follow ABCs (Airway, Breathing, Circulation) measures for resuscitation.
    • Gastrointestinal Decontamination:

      • Important in cases of overdose or severe toxicity.
    • Hypokalemia Management:

      • Chronic toxicity risk due to loop diuretics, diarrhea, or inadequate dietary potassium intake.

    Investigations

    • Cardiac:

      • Monitor for severe refractory shock and hypotension.
    • Respiratory:

      • Look for pulmonary edema, cough, and dyspnea.
    • Hepatic:

      • Centrilobular necrosis may be indicative of significant liver damage.
    • Metabolic:

      • Assess for signs of metabolic acidosis which could complicate patient condition.

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    Description

    This quiz covers various categories of antidepressants, focusing on selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants. Explore their therapeutic uses including treatments for depression, panic disorders, and migraine prophylaxis. Test your knowledge on these important mental health medications.

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