Antidepressant Medications

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Which neurotransmitter is involved in regulating body homeostasis?

Dopamine
Acetylcholine
Serotonin (correct)
Glutamate

What is the primary function of GABA receptors in the brain?

Excitation
Inhibition (correct)
Regulation of sleep-wake cycles
Modulation

Which neurotransmitter is involved in the construction of consciousness?

Dopamine
Glutamate
Acetylcholine (correct)
Serotonin

What is the duration of ion flow in/out of the neuron?

Milliseconds (A) Signup and view all the answers

Which type of receptors are involved in fast neurotransmission?

Ionotropic receptors (B) Signup and view all the answers

What is a common effect of the serotonin reuptake inhibitors?

Sedation (B) Signup and view all the answers

What is the characteristic of monoamine neurotransmitters?

They can be either excitatory or inhibitory depending on the state of the cell (A) Signup and view all the answers

Which antidepressant is a selective serotonin reuptake inhibitor?

Citalopram (D) Signup and view all the answers

What is the effect of fluoxetine on the neurotransmitter dopamine?

It has no effect on dopamine levels (C) Signup and view all the answers

What is the effect of nefazodone on sedation?

It increases sedation (A) Signup and view all the answers

Which antidepressant has a high affinity for the serotonin and norepinephrine receptors?

Venlafaxine (A) Signup and view all the answers

Which antidepressant does not have an anti-muscarinic effect?

Citalopram (D) Signup and view all the answers

Where do almost all norepinephrine pathways in the brain originate from?

Locus coeruleus in the midbrain (B) Signup and view all the answers

What is the function of monoamine oxidase in the nervous system?

To deaminate catecholamines (A) Signup and view all the answers

What is the effect of cocaine on the reuptake of norepinephrine?

It inhibits the reuptake of norepinephrine (B) Signup and view all the answers

Which neurotransmitter system is involved in anxiety, sleep, and sexual behavior?

Serotonin system (D) Signup and view all the answers

What is the relationship between stress and learning?

A small amount of stress always improves learning (B) Signup and view all the answers

What is the function of the hypothalamus in the norepinephrine system?

Regulation of endocrine response (A) Signup and view all the answers

Which of the following antidepressants is a 5-HT uptake inhibitor?

Venlafaxine (B) Signup and view all the answers

What is a major advantage of Monoamine Uptake Inhibitors compared to tricyclic antidepressants?

Fewer side effects (C) Signup and view all the answers

Which of the following is a potential risk of using Monoamine Uptake Inhibitors?

Increased risk of cardiac dysrhythmias (A) Signup and view all the answers

What is the mechanism of action of Mirtazapine?

Blocks α2 adrenoceptors and 5-HT2C receptors (C) Signup and view all the answers

Which of the following antidepressants is also used to treat nicotine dependence?

Bupropion (D) Signup and view all the answers

What is a unique feature of Duloxetine?

Is used to treat neuropathic pain and fibromyalgia (D) Signup and view all the answers

What is the purpose of antidepressants?

To increase the levels of circulating neurotransmitters in the synapse (C) Signup and view all the answers

What is a characteristic of individuals with high levels of serotonin?

They exhibit obsessive-compulsive disorders (D) Signup and view all the answers

What is the mechanism of action of Fluoxetine/Prozac?

It blocks the SERT (D) Signup and view all the answers

What is a common animal model of depression?

All of the above (D) Signup and view all the answers

What is a limitation of antidepressant clinical trials?

Large placebo effects (A) Signup and view all the answers

What is the name of the receptor involved in the regulation of serotonergic release?

α2-AR (D) Signup and view all the answers