Antidepressant Medications
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Questions and Answers

Which neurotransmitter is involved in regulating body homeostasis?

  • Dopamine
  • Acetylcholine
  • Serotonin (correct)
  • Glutamate
  • What is the primary function of GABA receptors in the brain?

  • Excitation
  • Inhibition (correct)
  • Regulation of sleep-wake cycles
  • Modulation
  • Which neurotransmitter is involved in the construction of consciousness?

  • Dopamine
  • Glutamate
  • Acetylcholine (correct)
  • Serotonin
  • What is the duration of ion flow in/out of the neuron?

    <p>Milliseconds</p> Signup and view all the answers

    Which type of receptors are involved in fast neurotransmission?

    <p>Ionotropic receptors</p> Signup and view all the answers

    What is a common effect of the serotonin reuptake inhibitors?

    <p>Sedation</p> Signup and view all the answers

    What is the characteristic of monoamine neurotransmitters?

    <p>They can be either excitatory or inhibitory depending on the state of the cell</p> Signup and view all the answers

    Which antidepressant is a selective serotonin reuptake inhibitor?

    <p>Citalopram</p> Signup and view all the answers

    What is the effect of fluoxetine on the neurotransmitter dopamine?

    <p>It has no effect on dopamine levels</p> Signup and view all the answers

    What is the effect of nefazodone on sedation?

    <p>It increases sedation</p> Signup and view all the answers

    Which antidepressant has a high affinity for the serotonin and norepinephrine receptors?

    <p>Venlafaxine</p> Signup and view all the answers

    Which antidepressant does not have an anti-muscarinic effect?

    <p>Citalopram</p> Signup and view all the answers

    Where do almost all norepinephrine pathways in the brain originate from?

    <p>Locus coeruleus in the midbrain</p> Signup and view all the answers

    What is the function of monoamine oxidase in the nervous system?

    <p>To deaminate catecholamines</p> Signup and view all the answers

    What is the effect of cocaine on the reuptake of norepinephrine?

    <p>It inhibits the reuptake of norepinephrine</p> Signup and view all the answers

    Which neurotransmitter system is involved in anxiety, sleep, and sexual behavior?

    <p>Serotonin system</p> Signup and view all the answers

    What is the relationship between stress and learning?

    <p>A small amount of stress always improves learning</p> Signup and view all the answers

    What is the function of the hypothalamus in the norepinephrine system?

    <p>Regulation of endocrine response</p> Signup and view all the answers

    Which of the following antidepressants is a 5-HT uptake inhibitor?

    <p>Venlafaxine</p> Signup and view all the answers

    What is a major advantage of Monoamine Uptake Inhibitors compared to tricyclic antidepressants?

    <p>Fewer side effects</p> Signup and view all the answers

    Which of the following is a potential risk of using Monoamine Uptake Inhibitors?

    <p>Increased risk of cardiac dysrhythmias</p> Signup and view all the answers

    What is the mechanism of action of Mirtazapine?

    <p>Blocks α2 adrenoceptors and 5-HT2C receptors</p> Signup and view all the answers

    Which of the following antidepressants is also used to treat nicotine dependence?

    <p>Bupropion</p> Signup and view all the answers

    What is a unique feature of Duloxetine?

    <p>Is used to treat neuropathic pain and fibromyalgia</p> Signup and view all the answers

    What is the purpose of antidepressants?

    <p>To increase the levels of circulating neurotransmitters in the synapse</p> Signup and view all the answers

    What is a characteristic of individuals with high levels of serotonin?

    <p>They exhibit obsessive-compulsive disorders</p> Signup and view all the answers

    What is the mechanism of action of Fluoxetine/Prozac?

    <p>It blocks the SERT</p> Signup and view all the answers

    What is a common animal model of depression?

    <p>All of the above</p> Signup and view all the answers

    What is a limitation of antidepressant clinical trials?

    <p>Large placebo effects</p> Signup and view all the answers

    What is the name of the receptor involved in the regulation of serotonergic release?

    <p>α2-AR</p> Signup and view all the answers

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