Podcast
Questions and Answers
What is the major difference between Dalteparin and Fondaparinux in terms of administration?
What is the major difference between Dalteparin and Fondaparinux in terms of administration?
- Dalteparin needs renal dose adjustment while Fondaparinux does not (correct)
- Dalteparin crosses the placenta while Fondaparinux does not
- Dalteparin is given SC every 12 hours while Fondaparinux is given SC once daily
- Dalteparin is given SC once daily while Fondaparinux is given IV every 12 hours
Which medication is used for the treatment and prophylaxis of deep vein thrombosis as well as in patients with heparin-induced thrombocytopenia (off label)?
Which medication is used for the treatment and prophylaxis of deep vein thrombosis as well as in patients with heparin-induced thrombocytopenia (off label)?
- Enoxaparin
- Fondaparinux (correct)
- Rivaroxaban
- Bivalirudin
Which novel oral anticoagulant (NOAC) is a direct thrombin inhibitor?
Which novel oral anticoagulant (NOAC) is a direct thrombin inhibitor?
- Rivaroxaban
- Edoxaban
- Dabigatran (correct)
- Apixaban
What is the mechanism of action of heparin (UFH)?
What is the mechanism of action of heparin (UFH)?
What is the primary method of action of Argatroban?
What is the primary method of action of Argatroban?
Why is intramuscular (IM) administration of heparin (UFH) not recommended?
Why is intramuscular (IM) administration of heparin (UFH) not recommended?
Which medication has dosing adjustments based on age, weight, and renal function for stroke prevention in nonvalvular atrial fibrillation?
Which medication has dosing adjustments based on age, weight, and renal function for stroke prevention in nonvalvular atrial fibrillation?
Which of the following coagulation factors is NOT inhibited by heparin (UFH)?
Which of the following coagulation factors is NOT inhibited by heparin (UFH)?
Why is IV infusion of heparin (UFH) preferred over subcutaneous injection for certain situations?
Why is IV infusion of heparin (UFH) preferred over subcutaneous injection for certain situations?
What is an example of SC dosing frequency for heparin (UFH) used for prophylaxis of DVT and PE?
What is an example of SC dosing frequency for heparin (UFH) used for prophylaxis of DVT and PE?
What is the end result of the Coagulation Cascade?
What is the end result of the Coagulation Cascade?
Which of the following statements about indirect thrombin inhibitors is true?
Which of the following statements about indirect thrombin inhibitors is true?
What is the general source of unfractionated heparin (UFH)?
What is the general source of unfractionated heparin (UFH)?
Why is unfractionated heparin (UFH) considered too large to be absorbed?
Why is unfractionated heparin (UFH) considered too large to be absorbed?
What is the main role of heparin (UFH) in pregnancy?
What is the main role of heparin (UFH) in pregnancy?
What is the specific activity of Fondaparinux (Arixtra®) in terms of increasing the neutralizing action of ATIII on activated Factor X?
What is the specific activity of Fondaparinux (Arixtra®) in terms of increasing the neutralizing action of ATIII on activated Factor X?
Which direct thrombin inhibitor was discontinued in 2012 due to anaphylactic reactions?
Which direct thrombin inhibitor was discontinued in 2012 due to anaphylactic reactions?
Which direct thrombin inhibitor has the longest half-life of 25 minutes?
Which direct thrombin inhibitor has the longest half-life of 25 minutes?
Which novel oral anticoagulant (NOAC) has a reversal agent called Praxbind (idarucizumab)?
Which novel oral anticoagulant (NOAC) has a reversal agent called Praxbind (idarucizumab)?
Which direct factor Xa inhibitor is indicated for preventing stroke in nonvalvular atrial fibrillation?
Which direct factor Xa inhibitor is indicated for preventing stroke in nonvalvular atrial fibrillation?
Which NOAC does not require routine anticoagulation tests?
Which NOAC does not require routine anticoagulation tests?
Which direct factor Xa inhibitor requires dose reduction with strong inhibitors of both CYP p450 3A4 and P-gp?
Which direct factor Xa inhibitor requires dose reduction with strong inhibitors of both CYP p450 3A4 and P-gp?
Which NOAC is recommended at a dose of 2.5 mg twice daily for DVT/PE prevention post hip or knee replacement?
Which NOAC is recommended at a dose of 2.5 mg twice daily for DVT/PE prevention post hip or knee replacement?
Which NOAC is contraindicated with prosthetic heart valves and severe liver impairment?
Which NOAC is contraindicated with prosthetic heart valves and severe liver impairment?
Which NOAC has a dosing regimen that includes 10 mg twice daily for the first week followed by 5 mg twice daily for DVT/PE treatment?
Which NOAC has a dosing regimen that includes 10 mg twice daily for the first week followed by 5 mg twice daily for DVT/PE treatment?
