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Questions and Answers
What is the primary mechanism of action for anticholinergic drugs?
What is the primary mechanism of action for anticholinergic drugs?
- Blocking acetylcholine receptors (correct)
- Stimulating acetylcholine production
- Inhibiting the breakdown of acetylcholine
- Enhancing acetylcholine release at nerve endings
Which of the following conditions is commonly treated with dicyclomine?
Which of the following conditions is commonly treated with dicyclomine?
- Hypertension
- Asthma
- Nausea and vomiting
- GI cramps and IBS (correct)
Ipratropium is typically administered via which route?
Ipratropium is typically administered via which route?
- Topical application
- Intramuscular injection
- Oral tablet
- Inhalation (correct)
Scopolamine is indicated for the treatment of which condition?
Scopolamine is indicated for the treatment of which condition?
Which of the following is a common contraindication for anticholinergic drugs?
Which of the following is a common contraindication for anticholinergic drugs?
Which of the following is a common adverse effect associated with anticholinergic drugs?
Which of the following is a common adverse effect associated with anticholinergic drugs?
Which of the following drug classes may have additive effects when administered with anticholinergics?
Which of the following drug classes may have additive effects when administered with anticholinergics?
Which route of administration is indicated for Dicyclomine?
Which route of administration is indicated for Dicyclomine?
Anticholinergic drugs inhibit what part of the nervous system?
Anticholinergic drugs inhibit what part of the nervous system?
An increase in heart rate can be associated with anticholinergic drugs, this is known as:
An increase in heart rate can be associated with anticholinergic drugs, this is known as:
Flashcards
Anticholinergics
Anticholinergics
Competitively block acetylcholine receptors at muscarinic cholinergic receptor sites, inhibiting parasympathetic postganglionic impulses.
Dicyclomine (Bentyl)
Dicyclomine (Bentyl)
An anticholinergic used to decrease peristalsis in GI cramps and IBS, administered intramuscularly.
Ipratropium
Ipratropium
An inhaled anticholinergic used for bronchospasms, COPD, and asthma.
Scopolamine
Scopolamine
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Anticholinergic Contraindications
Anticholinergic Contraindications
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Anticholinergic Adverse Effects
Anticholinergic Adverse Effects
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Anticholinergic Drug-Drug Interactions
Anticholinergic Drug-Drug Interactions
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Study Notes
- Anticholinergics competitively block acetylcholine receptors at muscarinic cholinergic receptor sites.
- These sites mediate the effects of parasympathetic postganglionic impulses.
Specific Anticholinergics
- Dicyclomine (Bentyl) treats GI cramps/IBS by decreasing peristalsis.
- It is administered intramuscularly only.
- Ipratropium manages bronchospasms, COPD, and asthma when inhaled.
- Scopolamine is used for nausea and vomiting and to reduce oral secretions.
Contraindications & Cautions
- Avoid use in conditions worsened by blocking the parasympathetic nervous system.
- Use caution in cardiac arrhythmias, tachycardia, myocardial ischemia, and impaired liver or kidney function.
- Hypertension and brain damage are also concerns.
Adverse Effects
- Adverse effects are related to parasympathetic nervous system inhibition.
- These include tachycardia, hypertension, urinary retention, and decreased GI motility/constipation.
Drug-Drug Interactions
- Concurrent use with other drugs possessing anticholinergic activity should be approached with caution.
- This includes antihistamines, antiparkinsonism drugs, MAOIs, TCAs, and phenothiazines.
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