Antibiotics and Resistance Quiz
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Questions and Answers

Quinolones :

  • Cause ototoxicity and nephrotoxicity (correct)
  • Inhibit cell wall synthesis
  • Good for atypical organism such as mycoplasma, chlamydia, legionella (correct)
  • Include tobramycin
  • Have broad spectrum against gram-positive bacteria (correct)
  • Each of the following concerning clindamycin is correct EXCEPT :

  • Causes diarrhea
  • Inhibits protein synthesis
  • Inhibits microbial DNA synthesis by blocking DNA gyrase (correct)
  • Has special role in treating streptococcus necrotizing fasciitis
  • Effective in anaerobes
  • The following antibacterial drugs inhibit bacterial protein synthesis EXCEPT :

  • Lincomycin
  • Erythromycin
  • Aminoglycoside
  • Vancomycin
  • Tetracyclines (correct)
  • The following are factors to be considered when chosen antibacterial drugs EXCEPT :

    <p>Patients height</p> Signup and view all the answers

    Bacterial antibiotic resistance may be :

    <p>Rarely by plasmid conjugation</p> Signup and view all the answers

    Systemic Inflammatory response syndrome

    <p>Number of red blood cells are increased</p> Signup and view all the answers

    In sepsis :

    <p>Rigors are not characteristic</p> Signup and view all the answers

    Study Notes

    19 - Quinolones

    • Have broad spectrum against gram-positive bacteria
    • Cause ototoxicity and nephrotoxicity
    • Include cell wall synthesis
    • Good for atypical organism such as mycoplasma, chlamydia, legionella
    • Effective in anarobes

    20 - Each of the following concerning clindamycin is correct EXCEPT:

    • Has special role in treating streptococcus necrotizing fasciitis
    • Inhibits protein synthesis
    • Effective in anaerobes
    • Causes diarrhea
    • Inhibits microbial DNA synthesis

    21 - The following antibacterial drugs inhibit bacterial protein synthesis EXCEPT:

    • Lincomycin
    • Vancomycin
    • Tetracyclines
    • Aminoglycoside
    • Erythromycin

    22 - The following are factors to be considered when choosing antibacterial drugs EXCEPT:

    • Patient age
    • Patient height
    • Cost
    • The causative agent
    • Allergy

    23 - Bacterial antibiotic resistance may be:

    • Due to cell permeability changes
    • By transduction which is uptake of the extracellular DNA by bacteria
    • Rarely by plasmid conjugation
    • Due to increased production of inhibited compound
    • Due to active efflux

    24 - Systemic Inflammatory Response Syndrome

    • Heart rate is decreased
    • Respiratory rate is decreased
    • Number of red blood cells are increased
    • Body temperature increased or decreased
    • PaCO2 > 12mmHg

    25 - In sepsis:

    • Rigors are not characteristic
    • Blood pressure is high
    • Vascular tone is reduced
    • Circulation support and anti infection drugs are not essential
    • Blood culture and sensitivity, not required

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    Description

    Test your understanding of quinolones, clindamycin, and protein synthesis inhibitors in this comprehensive quiz. Delve into factors affecting antibiotic choice and explore the mechanisms behind bacterial resistance. This quiz is ideal for students studying pharmacology and microbiology.

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