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Questions and Answers
A patient receiving a beta-lactam antibiotic develops a skin rash, shortness of breath, and swelling of the lips and tongue. Which of the following is the MOST likely adverse effect?
A patient receiving a beta-lactam antibiotic develops a skin rash, shortness of breath, and swelling of the lips and tongue. Which of the following is the MOST likely adverse effect?
- Nephrotoxicity
- Allergic reaction (correct)
- Ototoxicity
- Gastrointestinal upset
A patient is prescribed vancomycin for a severe infection. To minimize the risk of 'Red Man Syndrome', what administration technique should the nurse employ?
A patient is prescribed vancomycin for a severe infection. To minimize the risk of 'Red Man Syndrome', what administration technique should the nurse employ?
- Administer the drug as a bolus.
- Administer the drug slowly via infusion. (correct)
- Administer the drug via intramuscular injection.
- Administer the drug rapidly over 30 minutes.
A young patient is prescribed tetracycline for acne. What potential adverse effect should be discussed with the patient and their parents?
A young patient is prescribed tetracycline for acne. What potential adverse effect should be discussed with the patient and their parents?
- Increased appetite
- Decreased sensitivity to sunlight
- Tooth discoloration (correct)
- Improved bone density
A patient taking erythromycin complains of nausea, vomiting, and diarrhea. Which of the following is the MOST likely cause of these symptoms?
A patient taking erythromycin complains of nausea, vomiting, and diarrhea. Which of the following is the MOST likely cause of these symptoms?
A patient receiving gentamicin develops hearing loss and balance problems. What is the MOST likely adverse effect causing these issues?
A patient receiving gentamicin develops hearing loss and balance problems. What is the MOST likely adverse effect causing these issues?
A patient is prescribed sulfamethoxazole/trimethoprim (TMP/SMX). What adverse effect should the patient be educated about regarding sun exposure?
A patient is prescribed sulfamethoxazole/trimethoprim (TMP/SMX). What adverse effect should the patient be educated about regarding sun exposure?
A patient taking ciprofloxacin reports sudden pain in their Achilles tendon after physical activity. What is the MOST likely adverse effect?
A patient taking ciprofloxacin reports sudden pain in their Achilles tendon after physical activity. What is the MOST likely adverse effect?
A patient develops severe diarrhea and abdominal cramping after being treated with clindamycin. Which of the following conditions is MOST likely causing these symptoms?
A patient develops severe diarrhea and abdominal cramping after being treated with clindamycin. Which of the following conditions is MOST likely causing these symptoms?
A patient taking metronidazole reports a persistent metallic taste in their mouth and is advised to avoid alcohol. Why is alcohol contraindicated with this medication?
A patient taking metronidazole reports a persistent metallic taste in their mouth and is advised to avoid alcohol. Why is alcohol contraindicated with this medication?
Which adverse effect is MOST associated with acyclovir and ganciclovir, requiring close monitoring of kidney function?
Which adverse effect is MOST associated with acyclovir and ganciclovir, requiring close monitoring of kidney function?
A patient taking oseltamivir (Tamiflu) for influenza reports experiencing new-onset confusion and agitation. What is the MOST appropriate action?
A patient taking oseltamivir (Tamiflu) for influenza reports experiencing new-onset confusion and agitation. What is the MOST appropriate action?
Which of the following adverse effects is associated with amphotericin B ('Ampho-terrible') and necessitates monitoring of serum electrolyte levels?
Which of the following adverse effects is associated with amphotericin B ('Ampho-terrible') and necessitates monitoring of serum electrolyte levels?
A patient is prescribed fluconazole for a fungal infection. Which of the following organ systems is MOST likely to be affected by the adverse effects of this medication?
A patient is prescribed fluconazole for a fungal infection. Which of the following organ systems is MOST likely to be affected by the adverse effects of this medication?
A patient is started on rifampin as part of tuberculosis treatment. What potential side effect should the patient be informed about that may affect the color of their bodily fluids?
A patient is started on rifampin as part of tuberculosis treatment. What potential side effect should the patient be informed about that may affect the color of their bodily fluids?
A patient receiving isoniazid (INH) for tuberculosis prophylaxis reports numbness and tingling in their hands and feet. What is the MOST likely cause of this?
A patient receiving isoniazid (INH) for tuberculosis prophylaxis reports numbness and tingling in their hands and feet. What is the MOST likely cause of this?
A patient taking pyrazinamide as part of their tuberculosis treatment experiences joint pain and elevated uric acid levels. Which adverse effect is MOST likely occurring?
A patient taking pyrazinamide as part of their tuberculosis treatment experiences joint pain and elevated uric acid levels. Which adverse effect is MOST likely occurring?
A patient being treated for tuberculosis with ethambutol reports blurred vision and difficulty distinguishing between colors. What specific adverse effect is the patient likely experiencing?
A patient being treated for tuberculosis with ethambutol reports blurred vision and difficulty distinguishing between colors. What specific adverse effect is the patient likely experiencing?
A patient with HIV is prescribed zidovudine. What hematological adverse effect is MOST commonly associated with this medication?
A patient with HIV is prescribed zidovudine. What hematological adverse effect is MOST commonly associated with this medication?
Efavirenz is prescribed to a female patient of childbearing age, what potential side effect is MOST important to discuss pre-treatment?
Efavirenz is prescribed to a female patient of childbearing age, what potential side effect is MOST important to discuss pre-treatment?
A patient taking ritonavir reports feeling nauseous and has been unable to keep down food. What is the MOST likely cause of these symptoms?
A patient taking ritonavir reports feeling nauseous and has been unable to keep down food. What is the MOST likely cause of these symptoms?
A patient is prescribed morphine for severe pain. What is the MOST significant adverse effect that requires ongoing monitoring?
A patient is prescribed morphine for severe pain. What is the MOST significant adverse effect that requires ongoing monitoring?
A pregnant patient is experiencing moderate pain. Which of the following opioid analgesics should be avoided due to potential risks to the fetus?
A pregnant patient is experiencing moderate pain. Which of the following opioid analgesics should be avoided due to potential risks to the fetus?
A patient has overdosed on an opioid medication. Which of the following medications is the MOST appropriate to administer?
A patient has overdosed on an opioid medication. Which of the following medications is the MOST appropriate to administer?
A patient is taking acetaminophen regularly for chronic pain. What is the maximum daily dose of acetaminophen to avoid hepatotoxicity?
A patient is taking acetaminophen regularly for chronic pain. What is the maximum daily dose of acetaminophen to avoid hepatotoxicity?
A patient taking ibuprofen for arthritis reports stomach pain and dark stools. What is the MOST likely cause of these symptoms?
A patient taking ibuprofen for arthritis reports stomach pain and dark stools. What is the MOST likely cause of these symptoms?
A patient with gout is prescribed allopurinol. What potential adverse effect should the patient be monitored for?
A patient with gout is prescribed allopurinol. What potential adverse effect should the patient be monitored for?
Which of the following adverse effects is associated with colchicine, used in the treatment of gout?
Which of the following adverse effects is associated with colchicine, used in the treatment of gout?
A patient taking sumatriptan for migraine headaches reports chest tightness and pressure. What is the MOST likely cause of this symptom?
A patient taking sumatriptan for migraine headaches reports chest tightness and pressure. What is the MOST likely cause of this symptom?
Which of the following medications is MOST likely to cause peripheral neuropathy as an adverse effect?
Which of the following medications is MOST likely to cause peripheral neuropathy as an adverse effect?
Which antibiotic is most likely to cause tooth discoloration as a significant adverse effect, particularly in young children?
Which antibiotic is most likely to cause tooth discoloration as a significant adverse effect, particularly in young children?
Which of the following medications used to treat infections carries the highest risk of causing Clostridium difficile colitis?
Which of the following medications used to treat infections carries the highest risk of causing Clostridium difficile colitis?
Which medication is notable for causing a disulfiram-like reaction when combined with alcohol?
Which medication is notable for causing a disulfiram-like reaction when combined with alcohol?
Which of the following antiviral medications requires careful monitoring for electrolyte imbalances and potential nephrotoxicity?
Which of the following antiviral medications requires careful monitoring for electrolyte imbalances and potential nephrotoxicity?
Which of the following drugs is commonly associated with red-orange discoloration of bodily fluids?
Which of the following drugs is commonly associated with red-orange discoloration of bodily fluids?
Which drug used in the treatment of TB is most likely to cause optic neuritis as a side effect?
Which drug used in the treatment of TB is most likely to cause optic neuritis as a side effect?
Which of the following medications used to treat HIV can lead to bone marrow suppression?
Which of the following medications used to treat HIV can lead to bone marrow suppression?
Among the common pain relievers, which one is known for its potential to cause liver damage with high doses or overuse?
Among the common pain relievers, which one is known for its potential to cause liver damage with high doses or overuse?
What is the main mechanism by which sumatriptan alleviates headaches?
What is the main mechanism by which sumatriptan alleviates headaches?
Flashcards
Beta-Lactams Adverse Effects
Beta-Lactams Adverse Effects
Allergic reactions, GI upset, seizures (high dose, renal impairment). Cephalosporins have cross-allergy with penicillins.
Vancomycin Adverse Effects
Vancomycin Adverse Effects
Nephrotoxicity, ototoxicity, Red Man Syndrome (infusion reaction).
Tetracycline Adverse Effects
Tetracycline Adverse Effects
Tooth discoloration, bone growth inhibition, photosensitivity.
Macrolides (Erythromycin) Adverse Effects
Macrolides (Erythromycin) Adverse Effects
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Aminoglycosides (Gentamicin) Adverse Effects
Aminoglycosides (Gentamicin) Adverse Effects
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Sulfonamides (TMP/SMX) Adverse Effects
Sulfonamides (TMP/SMX) Adverse Effects
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Fluoroquinolones (Ciprofloxacin) Adverse Effects
Fluoroquinolones (Ciprofloxacin) Adverse Effects
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Clindamycin Adverse Effects
Clindamycin Adverse Effects
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Metronidazole Adverse Effects
Metronidazole Adverse Effects
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Acyclovir / Ganciclovir Adverse Effects
Acyclovir / Ganciclovir Adverse Effects
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Oseltamivir (Tamiflu) Adverse Effects
Oseltamivir (Tamiflu) Adverse Effects
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Amphotericin B (Ampho-terrible) Adverse Effects
Amphotericin B (Ampho-terrible) Adverse Effects
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Azoles (Fluconazole, Itraconazole) Adverse Effects
Azoles (Fluconazole, Itraconazole) Adverse Effects
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Rifampin Adverse Effects
Rifampin Adverse Effects
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Isoniazid Adverse Effects
Isoniazid Adverse Effects
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Pyrazinamide Adverse Effects
Pyrazinamide Adverse Effects
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Ethambutol Adverse Effects
Ethambutol Adverse Effects
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Zidovudine Adverse Effects
Zidovudine Adverse Effects
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Efavirenz Adverse Effects
Efavirenz Adverse Effects
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Ritonavir Adverse Effects
Ritonavir Adverse Effects
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Opioids (Morphine, Fentanyl, etc.) Adverse Effects
Opioids (Morphine, Fentanyl, etc.) Adverse Effects
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Acetaminophen Adverse Effects
Acetaminophen Adverse Effects
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Ibuprofen Adverse Effects
Ibuprofen Adverse Effects
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Allopurinol Adverse Effects
Allopurinol Adverse Effects
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Colchicine Adverse Effects
Colchicine Adverse Effects
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Sumatriptan Adverse Effects
Sumatriptan Adverse Effects
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Study Notes
Antibiotics
Beta-Lactams (Penicillins, Cephalosporins, Carbapenems)
- Adverse effects include allergic reactions, GI upset, and seizures, especially with high doses or renal impairment
- Memory trick: "Beta makes your Belly and Brain Bounce" for GI upset and seizures
- Be aware of cross-allergy between cephalosporins and penicillins
Vancomycin
- Adverse effects are nephrotoxicity, ototoxicity, and Red Man Syndrome, the latter being an infusion reaction
- Memory trick: "VAN go slow or you'll glow" to infuse slowly and avoid Red Man Syndrome
Tetracycline
- Adverse effects consist of tooth discoloration, bone growth inhibition, and photosensitivity
- Memory trick: "Tetra Teeth Tan Trouble" to remember teeth stains and sun sensitivity
Macrolides (Erythromycin)
- Adverse effects include GI upset, QT prolongation, and CYP3A4 interactions
- Memory trick: "E for EKG" to watch QT interval, and "Macrolides Make you HURL"
Aminoglycosides (Gentamicin)
- Adverse effects involve nephrotoxicity and ototoxicity
- Memory trick: "A Mean GNAT" for Gentamicin, Nephrotoxicity, Aminoglycoside, and Tinnitus
Sulfonamides (TMP/SMX)
- Adverse effects: Rash (SJS), hyperkalemia, crystalluria, and photosensitivity
- Memory trick: "Sulfa SSSSucks for Skin, Sun, Stones"
Fluoroquinolones (Ciprofloxacin)
- Adverse effects include tendon rupture, QT prolongation, and CNS effects
- Memory trick: "Flox like a tendon pop"
Clindamycin
- Adverse effects: C. diff colitis
- Memory trick: "Clean-da-gut but causes Clostridium!"
Metronidazole
- Adverse effects: Metallic taste and disulfiram reaction with alcohol
- Memory trick: "Metro = Metallic + no Merlot"
Antivirals
Acyclovir / Ganciclovir
- Adverse effects of Acyclovir is Nephrotoxicity (hydrate!) and Ganciclovir is bone marrow suppression
- Memory trick for Acyclovir: "A kidney concern"
- Memory trick for Ganciclovir: "Guts (marrow) get hit"
Oseltamivir (Tamiflu)
- Adverse Effects: Nausea, vomiting, rare neuropsych symptoms
- Memory trick: "Tamiflu can Mess with Mind and Meals"
Antifungals
Amphotericin B (Ampho-terrible)
- Adverse effects include nephrotoxicity, electrolyte imbalance (↓K, ↓Mg), and infusion reactions
- Memory trick: "Ampho-terrible for your kidneys"
Azoles (Fluconazole, Itraconazole)
- Adverse effects: Hepatotoxicity, CYP interactions
- Memory trick: "Azoles = A Liver Load"
Antituberculars (RIPE)
- R - Rifampin: Causes red-orange fluids and hepatotoxicity; memory trick: "Rifampin = Red fluids"
- I - Isoniazid: Causes peripheral neuropathy and hepatotoxicity; memory trick: "INH = Injures Nerves and Hepa"
- P - Pyrazinamide: Causes hyperuricemia and hepatotoxicity; memory trick: "Pee = Uric acid up"
- E - Ethambutol: Causes optic neuritis; memory trick: "E = Eye problems"
Antiretrovirals (HIV)
- Zidovudine: Causes bone marrow suppression
- Efavirenz: Causes CNS side effects and is teratogenic
- Ritonavir: CYP inhibitor, causes GI upset
- General tip: Always monitor for resistance, adherence, and food interactions
Pain Management
Opioids (Morphine, Fentanyl, etc.)
- Adverse effects are respiratory depression, constipation, and sedation
- Memory trick: "Morphine Means Minimal Movement"
- Meperidine and Codeine are to be avoided in pregnancy
- Naloxone is a reversal agent
Non-Opioids
- Acetaminophen: Causes hepatotoxicity, with a max dose of 4g/day
- Ibuprofen: Causes GI upset and nephrotoxicity
- Memory trick: "Ibuprofen = I Burn gut and I Block kidneys"
Gout
- Allopurinol: Hypersensitivity, rash
- Colchicine: GI upset, myopathy
- memory trick: “Colchicine = Colon Chaos”
Headache
- Sumatriptan: Causes chest pressure and serotonin syndrome
- Memory trick: "Suma-Squeeze" (vasoconstriction = chest pain)
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