Anti-anginal Drugs & Mechanisms Quiz
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Questions and Answers

What is the primary cause of angina pectoris?

  • Insufficient coronary blood flow (correct)
  • Complete blockage of coronary arteries
  • Inadequate myocardial oxygen consumption
  • Accumulation of lactic acid
  • Which risk factor is NOT associated with angina?

  • Regular physical activity (correct)
  • Obesity
  • Diabetes
  • High cholesterol
  • What type of angina is associated with atheromatous plaques that partially occlude one or more coronary arteries?

  • Variant angina
  • Microvascular angina
  • Unstable angina
  • Atherosclerotic angina (correct)
  • What type of pain is characteristic of atherosclerotic angina?

    <p>Sudden, severe, crushing chest pain radiating to the neck, jaw, back, and arms</p> Signup and view all the answers

    What percentage of angina cases does atherosclerotic angina constitute?

    <p>90%</p> Signup and view all the answers

    What is the main cause of vasospastic angina?

    <p>Reversible spasm of coronaries</p> Signup and view all the answers

    Which of the following is NOT a pharmacologic therapy for angina?

    <p>Platelet aggregation inhibitors</p> Signup and view all the answers

    What is the primary role of nitric oxide (NO) in the cardiovascular system?

    <p>Mediate relaxation of the corpus cavernosum</p> Signup and view all the answers

    What was prescribed to Alfred Nobel to ease his chest pain when he developed angina in 1890?

    <p>Glyceryl trinitrate (nitroglycerin)</p> Signup and view all the answers

    Why should nitroglycerin tablets be kept in tightly closed glass containers?

    <p>To avoid plastic surface adsorption</p> Signup and view all the answers

    Study Notes

    Angina Pectoris

    • Primary cause of angina pectoris: reduction in blood flow to the heart muscle due to coronary artery disease

    Risk Factors

    • NOT associated with angina: unknown

    Types of Angina

    • Atherosclerotic angina: associated with atheromatous plaques that partially occlude one or more coronary arteries
    • Characteristic pain of atherosclerotic angina: squeezing, pressure, or tightness in the chest, arm, or jaw
    • Atherosclerotic angina constitutes: approximately 90% of angina cases

    Vasospastic Angina

    • Main cause: coronary artery spasm
    • Pain pattern: recurrent episodes of chest pain at rest, often during the night or early morning hours

    Pharmacologic Therapy for Angina

    • NOT a pharmacologic therapy for angina: antibiotics

    Nitric Oxide (NO)

    • Primary role in the cardiovascular system: vasodilation, reducing blood pressure

    Historical Note

    • Alfred Nobel's treatment for angina in 1890: nitroglycerin

    Nitroglycerin

    • Storage requirements: tightly closed glass containers to prevent degradation by moisture and light

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    Description

    Test your knowledge of anti-anginal drugs and their mechanisms with this quiz. Explore topics such as organic nitrates, β-blockers, calcium channel blockers, and other medications used to treat angina.

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