Animal Respiratory System Evaluation

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Questions and Answers

What is the principle exploited by body plethysmography?

  • Measurement of respiratory rate
  • Calculation of tidal volume
  • Detection of changes in box pressure (correct)
  • Assessment of inspiratory time

Which parameter is not measured in the Penh system for unrestrained animals?

  • Residual volume (RV)
  • Expiratory time (Te)
  • Total lung capacity (TLC)
  • Inspiratory time (Ti) (correct)

What is the major difference between head-out plethysmography in conscious rodents and whole-body plethysmography?

  • Detection of chest wall movements
  • Measurement of total lung capacity
  • Capture of true respiratory flow (correct)
  • Assessment of inspiratory time

What does the Penh system for unrestrained animals screen for?

<p>Pulmonary airway reactivity (D)</p> Signup and view all the answers

How are animals prepared for head-out plethysmography in conscious rodents?

<p>They are trained for 5 days in increasing time periods (A)</p> Signup and view all the answers

Which law is exploited by body plethysmography?

<p>Boyle's law (D)</p> Signup and view all the answers

What is the purpose of the head chamber in the body plethysmograph?

<p>To supply an opening for spraying the tested drug (D)</p> Signup and view all the answers

Which parameter is used to quantify an elongation of the period from the end of the expiration until the start of the new inspiration?

<p>Time of brake (TB) (C)</p> Signup and view all the answers

Why is orotracheal intubation used in spontaneously breathing, anesthetized animals?

<p>To calculate lung resistance (RL) (D)</p> Signup and view all the answers

What is the advantage of non-invasive spirometry over invasive spirometry?

<p>The breathing pattern is nearly natural (A)</p> Signup and view all the answers

What is the disadvantage of invasive spirometry compared to non-invasive spirometry?

<p>Less sensitive and less specific (D)</p> Signup and view all the answers

What is measured by a pneumotachograph connected to the body chamber?

<p>Flow rate and volume (A)</p> Signup and view all the answers

Which parameter can be calculated by processing tidal respiratory flow and transpulmonary pressure?

<p>Lung resistance (RL) (C)</p> Signup and view all the answers

What is the purpose of the neck collar in the body plethysmograph?

<p>To protrude the head of each animal (A)</p> Signup and view all the answers

Which parameter quantifies an elongation of the period from the end of the inspiration until the start of the expiration?

<p>Time of brake (TB) (C)</p> Signup and view all the answers

Which part of the apparatus is supplied with an opening through which the tested drug is sprayed?

<p>Head Chamber (D)</p> Signup and view all the answers

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