Animal Respiratory System Evaluation
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Questions and Answers

What is the principle exploited by body plethysmography?

  • Measurement of respiratory rate
  • Calculation of tidal volume
  • Detection of changes in box pressure (correct)
  • Assessment of inspiratory time
  • Which parameter is not measured in the Penh system for unrestrained animals?

  • Residual volume (RV)
  • Expiratory time (Te)
  • Total lung capacity (TLC)
  • Inspiratory time (Ti) (correct)
  • What is the major difference between head-out plethysmography in conscious rodents and whole-body plethysmography?

  • Detection of chest wall movements
  • Measurement of total lung capacity
  • Capture of true respiratory flow (correct)
  • Assessment of inspiratory time
  • What does the Penh system for unrestrained animals screen for?

    <p>Pulmonary airway reactivity</p> Signup and view all the answers

    How are animals prepared for head-out plethysmography in conscious rodents?

    <p>They are trained for 5 days in increasing time periods</p> Signup and view all the answers

    Which law is exploited by body plethysmography?

    <p>Boyle's law</p> Signup and view all the answers

    What is the purpose of the head chamber in the body plethysmograph?

    <p>To supply an opening for spraying the tested drug</p> Signup and view all the answers

    Which parameter is used to quantify an elongation of the period from the end of the expiration until the start of the new inspiration?

    <p>Time of brake (TB)</p> Signup and view all the answers

    Why is orotracheal intubation used in spontaneously breathing, anesthetized animals?

    <p>To calculate lung resistance (RL)</p> Signup and view all the answers

    What is the advantage of non-invasive spirometry over invasive spirometry?

    <p>The breathing pattern is nearly natural</p> Signup and view all the answers

    What is the disadvantage of invasive spirometry compared to non-invasive spirometry?

    <p>Less sensitive and less specific</p> Signup and view all the answers

    What is measured by a pneumotachograph connected to the body chamber?

    <p>Flow rate and volume</p> Signup and view all the answers

    Which parameter can be calculated by processing tidal respiratory flow and transpulmonary pressure?

    <p>Lung resistance (RL)</p> Signup and view all the answers

    What is the purpose of the neck collar in the body plethysmograph?

    <p>To protrude the head of each animal</p> Signup and view all the answers

    Which parameter quantifies an elongation of the period from the end of the inspiration until the start of the expiration?

    <p>Time of brake (TB)</p> Signup and view all the answers

    Which part of the apparatus is supplied with an opening through which the tested drug is sprayed?

    <p>Head Chamber</p> Signup and view all the answers

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