Animal Pharming and Transgenic Proteins

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17 Questions

What is one of the benefits of using plants as bioreactors for the production of therapeutic proteins?

Lack of animal pathogenic contaminants

What is a crucial aspect of efficient plant production systems for recombinant antibodies?

Optimal combination of transgene expression regulatory elements

What is a potential concern regarding food products derived from transgenic animals?

Unknown risk factors

What is a type of protein that can be produced through plant biopharming?

Monoclonal antibodies

What is an advantage of using transgenic crops compared to transgenic animals?

Faster generation times

What is a challenge associated with transgenic animals?

Variable gene expression levels

What is the primary reason for the lack of transgenic-plant-derived pharmaceuticals in commercial production?

Lack of profit incentive for private industry

What is the benefits of expressing antifungal peptides in Arabidopsis plants?

Improved disease resistance from fungi

What is the purpose of using a pressurized hand-held gene gun in plant transformation?

To shoot DNA-coated gold particles into plant tissue

What is an advantage of microparticle bombardment in plant transformation?

Ability to transform recalcitrant species

What is an advantage of co-transformation with multiple transgenes?

Introduction of multiple genes of interest with one selectable marker

What is the use of mice in biomedical research?

Testing of new medical treatments

What is one of the benefits of plant cell cultures in biopharmaceutical production?

Reduced regulatory costs

Which plant cell strains are known for being fast-growing and robust?

Nicotiana tabacum-1 and BY-2

What is a major limitation of plant cell cultures in biopharmaceutical production?

Low productivity

What is required to increase the efficiency of plant cell cultures in biopharmaceutical production?

A systematic strategy to maximize the efficiency of all stages of the production pipeline

What is the goal for increasing productivity in plant cell cultures?

10-50 fold increase

Discover the potential of animal pharming, a technology that harnesses the properties of milk to produce functional enzymes, antibodies, and structural proteins. Learn about the strategy of using mammary-specific genes to direct expression of soluble transgenic proteins and its pharmaceutical applications.

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