Animal Cell Structure: Cytoskeleton and Cell Junctions

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is NOT a primary function of the cytoskeleton?

  • Maintaining cell shape
  • Generating energy for the cell (correct)
  • Providing cellular motility
  • Positioning organelles within cells

What distinguishes the cytoskeleton from the body's skeletal system?

  • The cytoskeleton is more stable and rigid
  • The cytoskeleton does not provide stability
  • The cytoskeleton rapidly disassembles and reassembles (correct)
  • The cytoskeleton is less dynamic

A cell requires the ability to resist compression. Which cytoskeletal element would be MOST suited to provide this function?

  • Intermediate filaments
  • Microfilaments
  • Microtubules (correct)
  • Actin filaments

Which of the following cellular structures is directly involved in the movement of organelles within a cell?

<p>Microtubules (C)</p> Signup and view all the answers

How do motor proteins facilitate the movement of organelles along microtubules?

<p>By 'walking' along the microtubules (A)</p> Signup and view all the answers

What is the primary function of the cortical network formed by microfilaments beneath the plasma membrane?

<p>To make the region less fluid and maintain cell shape (C)</p> Signup and view all the answers

Which type of cytoskeletal element is MOST involved in muscle contraction?

<p>Actin filaments (B)</p> Signup and view all the answers

Which of the following is an example of a function primarily carried out by actin filaments?

<p>Amoeboid movement (B)</p> Signup and view all the answers

What characteristic differentiates intermediate filaments from microtubules and microfilaments?

<p>Intermediate filaments are less dynamic and form relatively permanent structures (B)</p> Signup and view all the answers

Which of the following proteins is a primary component of intermediate filaments?

<p>Keratin (B)</p> Signup and view all the answers

What is the MOST likely function of intermediate filaments containing lamins?

<p>Maintaining the structural integrity of the nucleus (B)</p> Signup and view all the answers

What type of cell junction forms a continuous seal, preventing the movement of fluid across cell layers?

<p>Tight junctions (B)</p> Signup and view all the answers

What is the primary function of desmosomes in tissues like muscle?

<p>To provide strong attachments between cells in sheets (B)</p> Signup and view all the answers

Which type of cell junction allows for rapid cell-to-cell communication through the passage of ions and small molecules?

<p>Gap junctions (C)</p> Signup and view all the answers

In which of the following scenarios would gap junctions be MOST beneficial?

<p>In cells that need to coordinate rapid responses, such as cardiac muscle cells (B)</p> Signup and view all the answers

What is the main role of the extracellular matrix (ECM) in tissues?

<p>Providing structural support and mediating interactions between cells (B)</p> Signup and view all the answers

How does the composition of the extracellular matrix (ECM) typically vary?

<p>It varies depending on the specific tissue and its functional requirements (D)</p> Signup and view all the answers

What is the process by which cells secrete the components of the extracellular matrix (ECM)?

<p>Constitutive exocytosis (C)</p> Signup and view all the answers

What is the MOST abundant glycoprotein found in the extracellular matrix (ECM)?

<p>Collagen (B)</p> Signup and view all the answers

Water is trapped within the ECM, resisting compression and helping retain tissue shape. This function relies primarily on ______.

<p>Proteoglycans (B)</p> Signup and view all the answers

Fibronectins and integrins mediate which key interaction?

<p>Communication between the ECM and the cell cytoskeleton (B)</p> Signup and view all the answers

Which of the following statements accurately describes the dynamic nature of the cytoskeleton?

<p>It rapidly assembles and disassembles, allowing for changes in cell shape and movement. (B)</p> Signup and view all the answers

A researcher is studying a cell that needs to withstand significant stretching forces. Which type of cell junction is MOST likely to be abundant in this cell?

<p>Desmosomes (D)</p> Signup and view all the answers

If a cell is unable to properly secrete collagen, what function would be MOST directly affected?

<p>The cell's contribution to the tensile strength of surrounding tissues. (A)</p> Signup and view all the answers

Consider a drug that inhibits the function of motor proteins associated with microtubules. What cellular process would be MOST directly affected?

<p>The cell's ability to transport vesicles to specific targets. (B)</p> Signup and view all the answers

Cardiac muscle cells require coordinated and rapid communication to contract efficiently. Which type of cell junction is MOST likely to facilitate this function?

<p>Gap junctions (B)</p> Signup and view all the answers

A mutation disrupts the ability of cells to produce keratin. Which tissue would be MOST affected by this mutation?

<p>Epithelial tissue, such as skin and hair (D)</p> Signup and view all the answers

Which of the following events would MOST likely occur if tight junctions in the epithelial cells lining the small intestine were compromised?

<p>Uncontrolled leakage of digestive fluids between cells (C)</p> Signup and view all the answers

After death, cells break down, but intermediate filaments can persist. What is an example of a structure composed of intermediate filaments that remains after cellular degradation?

<p>Hair (D)</p> Signup and view all the answers

Which of the following BEST describes the roles of both fibronectin and integrin?

<p>Fibronectin attaches cells to the ECM; integrin connects the ECM to the cytoskeleton (B)</p> Signup and view all the answers

A researcher discovers a new cell type that lacks microtubules. What function would this cell MOST likely be unable to perform?

<p>Intracellular transport of organelles (C)</p> Signup and view all the answers

If a tissue sample shows a significant decrease in proteoglycans, which characteristic of the extracellular matrix (ECM) would be MOST directly affected?

<p>Resistance to compression (B)</p> Signup and view all the answers

A researcher treats cells with a compound that prevents actin subunits from polymerizing into microfilaments. Which cellular process would be MOST affected?

<p>Muscle contraction (D)</p> Signup and view all the answers

In a cell undergoing mechanical stress, which type of junction would be MOST important for providing structural integrity and preventing tissue tearing?

<p>Desmosomes (C)</p> Signup and view all the answers

Which property of microtubules directly contributes to their role in maintaining cell shape and resisting compression?

<p>Their rigid, hollow structure (C)</p> Signup and view all the answers

In some disease states, neurofilaments can malfunction. Where would these problems MOST likely manifest?

<p>In the structural support of nerve cells (B)</p> Signup and view all the answers

Hyaluronic acid is included in some beauty products to retain moisture to 'plump' skin. Where is hyaluronic acid primarily found, and how does it retain the moisture?

<p>Within the extracellular matrix, acting as a glycosaminoglycan in proteoglycans (D)</p> Signup and view all the answers

Which type of cytoskeletal filament is involved in cytoplasmic streaming in plants?

<p>Microfilaments (A)</p> Signup and view all the answers

Which of the following cell junctions is most like 'rivets' in that they provide attachments between sheets of cells?

<p>Desmosomes (D)</p> Signup and view all the answers

What is the primary function of cilia on cells in the respiratory tract?

<p>Moving mucus and trapped particles out of the lungs (D)</p> Signup and view all the answers

Which of the following BEST describes how microtubules facilitate cellular movement?

<p>By providing a track for motor proteins to transport organelles and vesicles. (A)</p> Signup and view all the answers

During embryonic development, cells migrate to specific locations to form tissues and organs. Which of the following is MOST crucial for guiding cell migration?

<p>The dynamic instability of microtubules and their interaction with motor proteins. (C)</p> Signup and view all the answers

A researcher observes that a particular cell type has an unusually high concentration of desmosomes. What can the researcher infer about the function of this cell type?

<p>It experiences significant mechanical stress and requires strong adhesion to neighboring cells. (B)</p> Signup and view all the answers

How do integrins facilitate communication between the extracellular matrix (ECM) and the cytoskeleton?

<p>By binding to ECM components on one side and linking to cytoskeletal filaments on the other. (B)</p> Signup and view all the answers

Many cancer cells can detach from the primary tumor and invade other tissues. Which alteration in cell junctions would MOST directly facilitate this process?

<p>Decreased expression of cell adhesion molecules that form desmosomes. (A)</p> Signup and view all the answers

Flashcards

Cytoskeleton Function

The cytoskeleton helps maintain cell shape and position of organelles. It rapidly disassembles and reassembles to allow cell shape changes.

Microtubules

Microtubules are composed of tubulin subunits and radiate from the centrosome. They resist compression to help maintain cell shape.

Microtubules and Motility

They provide motility via flagella and cilia. Motor proteins 'walk' organelles along them, transporting cargo.

Microfilaments

Microfilaments are a double chain of actin subunits that form linear strands and 3-dimensional networks. They resist tension and help maintain cell shape.

Signup and view all the flashcards

Actin and Myosin

Interactions between actin and motor proteins (myosin) support cell movement and muscle contraction.

Signup and view all the flashcards

Microfilaments in Non-Animals

Non-animal examples include amoeboid movement and cytoplasmic streaming in plants.

Signup and view all the flashcards

Intermediate Filaments

Intermediate filaments are made of various proteins (keratins, lamins, neurofilaments) and form relatively permanent cellular structures.

Signup and view all the flashcards

Intermediate Filaments Function

They help maintain cell shape and anchor organelles. They persist even after the cell dies.

Signup and view all the flashcards

Tight Junctions

They hold neighboring cells tightly pressed together, forming a continuous seal that prevents fluid movement across cell layers.

Signup and view all the flashcards

Desmosomes

Desmosomes provide attachments between cells via intermediate filaments. They act like rivets, connecting muscle cells.

Signup and view all the flashcards

Gap Junctions

Gap junctions are cytoplasmic contacts between cells that allow ions and small molecules to pass, enabling rapid intercellular communication.

Signup and view all the flashcards

Extracellular Matrix (ECM)

The ECM is composed of material secreted by cells. It provides structural support and varies between tissues.

Signup and view all the flashcards

ECM Components

The ECM’s most abundant glycoprotein is collagen which provides tensile strenght. Proteoglycans found in the ECM trap water to resist compression.

Signup and view all the flashcards

ECM Connection Proteins

Other glycoproteins, like fibronectins, attach cells to the ECM. Membrane proteins, like integrins, connect the ECM to the cytoskeleton.

Signup and view all the flashcards

Study Notes

Lecture 5 Objectives

  • Identify the major components of the cytoskeleton: microtubules, microfilaments, and intermediate filaments.
  • Explain how these structures regulate cell shape.
  • Outline the importance of cell junctions: tight, gap, and desmosomes.
  • Describe the composition and origin of the extracellular matrix.

Animal Cell Structures

  • Inside the animal cell: the cytoskeleton provides support and mobility.
  • Outside the animal cell: the extracellular matrix is made of glycoproteins.
  • Animal cells connect via cell junctions.

The Cytoskeleton

  • Helps maintain cell shape.
  • Helps maintain the position of organelles within cells.
  • Rapidly disassembles and reassembles, allowing for rapid changes in cell shape.
  • The cytoskeleton is highly dynamic while still providing stability.

Cytoskeleton Composition

  • The cytoskeleton is made of three main components: Microtubules, Microfilaments, and Intermediate Filaments.

Microtubules

  • Composed of tubulin subunits.
  • Radiate out from an organizing center called the centrosome.
  • Resist compression, helping maintain cell shape.
  • Can also provide cell motility.
  • Can provide "snake-like" motion via flagella.
  • Can provide "rowing-like" motion via cilia.
  • If cells are fixed in place, the beating of cilia moves fluid past them.
  • Involved in organelle motility within the cell.
  • ATP-powered motor proteins can "walk" organelles along microtubules.
  • Allows vesicles, or other organelles, to be transported to specific targets within the cell.

Microfilaments

  • Are a double chain of actin subunits.
  • Form linear strands.
  • Form 3-dimensional networks using branching proteins.
  • Resist tension.
  • The cortical network under the plasma membrane helps make this region less fluid, maintaining cell shape.
  • Interactions between actin and motor proteins such as myosin support cell movement.
  • Actin-myosin interactions allow muscle contraction.
  • Enable amoeboid movement.
  • Enable cytoplasmic streaming in plants.

Intermediate Filaments

  • Made of various proteins, including keratins in hair, lamins in the nucleus, and neurofilaments in neurons.
  • Supercoiled into “cables”.
  • Less dynamic than microtubules or microfilaments.
  • Form relatively permanent cellular structures.
  • Help maintain cell shape.
  • Help anchor organelles.
  • May also remain after the cell that made them has died, as in hair and the outer layer of skin.

Cell Junctions

  • Three major types of cell junctions: Tight Junctions, Desmosomes, and Gap Junctions.
  • Each type differs in structure and function.

Tight Junctions

  • Hold neighboring cells tightly pressed together to form a continuous seal.
  • Prevent movement of fluid across cell layers.

Desmosomes

  • Anchoring junctions, that provide attachments between sheets of cells e.g. muscle.
  • Act like rivets (a “torn muscle" could mean a torn desmosome)
  • Connected into the cell by intermediate filaments.

Gap Junctions

  • A point of cytoplasmic contact between two cells.
  • Ions and small molecules can pass from cell to cell.
  • Allow for rapid cell-to-cell (intercellular) communication.

Extracellular Matrix (ECM)

  • In many tissues, cells do not make direct contact with other cells.
  • Cells lie within the ECM, the composition of which varies between tissues.
  • The ECM is composed of material secreted by cells.
  • Secretion of ECM materials occurs via constitutive exocytosis.
  • Most ECM proteins are glycoproteins (protein with added carbohydrates).
  • Collagen, a glycoprotein, is the most abundant ECM glycoprotein.
  • Collagen fibers have great tensile strength.
  • Collagen fibers are embedded in a proteoglycan complex matrix.
  • Proteoglycans are proteins with extensive sugar additions.
  • Proteoglycans trap water within the ECM.
  • Water resists compression and thus helps retain tissue shape.
  • The ECM is important in providing strength and resilience to skin.
  • Other glycoproteins (fibronectins) attach cells to the ECM.
  • Membrane proteins (integrins) connect the ECM to the cytoskeleton.
  • Integrins provide a communication link from ECM to the cell interior.

Lecture 5 Summary

  • The cytoskeleton is dynamic, provides structure and stability, and has three main components.
  • Microtubules, microfilaments, and intermediate filaments have distinct structures and therefore functions within the cell.
  • Tight junctions, desmosomes, and gap junctions are important for adhesion and communication between cells.
  • The extracellular matrix (ECM) is the non-cellular part of tissues secreted via constitutive exocytosis.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Use Quizgecko on...
Browser
Browser