Animal Body Systems - Neuron Potentials
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Questions and Answers

Which of the following is NOT a major role of the nervous system?

  • Processes and integrates information
  • Collects information from the internal or external environment
  • Regulates the production and release of hormones (correct)
  • Transmits information to effector organs or cells
  • Which of these statements BEST describes the difference between a neuron and a nerve?

  • A neuron is a type of specialized cell, while a nerve is a bundle of axons. (correct)
  • A neuron is part of a nerve, while a nerve contains multiple neurons.
  • A neuron is responsible for collecting information, while a nerve is responsible for transmitting information.
  • A nerve is a single axon, while a neuron can have multiple axons.
  • What is the primary function of a synapse?

  • To facilitate communication between neurons or between a neuron and an effector cell. (correct)
  • To regulate the flow of blood to the brain.
  • To generate electrical impulses within the neuron.
  • To provide a structural support for the neuron.
  • Which of the following is NOT an effector cell?

    <p>A red blood cell (B)</p> Signup and view all the answers

    Which statement BEST describes the role of the endocrine system in coordination with the nervous system?

    <p>The endocrine system and nervous system work together, providing both rapid and long-term regulatory processes for homeostasis. (C)</p> Signup and view all the answers

    What is the primary difference between a neuron and a regular cell regarding their electrical properties?

    <p>Neurons have special mechanisms that allow them to regulate their membrane potential and currents. (B)</p> Signup and view all the answers

    What is the typical range for the size of a membrane potential (MP) in living cells?

    <p>-10 to -90 mV (B)</p> Signup and view all the answers

    What is the definition of current in the context of electricity?

    <p>The flow of electrical charge between two regions. (B)</p> Signup and view all the answers

    What is the primary reason for the resting membrane potential of a cell?

    <p>The unequal distribution of ions across the cell membrane. (C)</p> Signup and view all the answers

    Which of the following are considered principle ions involved in the resting membrane potential?

    <p>Sodium (Na+) and Potassium (K+) (B)</p> Signup and view all the answers

    Which of the following is NOT a type of membrane potential found in excitable cells?

    <p>Synaptic potential (SP) (C)</p> Signup and view all the answers

    What is the typical resting membrane potential of a neuron axon?

    <p>-70 mV (D)</p> Signup and view all the answers

    What is the most accurate description of membrane potential?

    <p>The unequal charge distribution across a cell membrane. (B)</p> Signup and view all the answers

    What is the main factor responsible for generating the additional -55 mV potential in neurons?

    <p>Passive diffusion of potassium ions through open potassium channels (D)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding the sodium-potassium pump?

    <p>It requires ATP to function. (A)</p> Signup and view all the answers

    The resting potential of neurons (-70 mV) is a result of the combined contributions of which three factors?

    <p>Sodium-potassium pump, leak channels, negative intracellular proteins (D)</p> Signup and view all the answers

    What is the primary function of an action potential in a neuron?

    <p>To conduct a signal from the axon hillock to the axon terminals. (A)</p> Signup and view all the answers

    What is the key difference between graded potentials and action potentials?

    <p>Graded potentials occur in dendrites and cell bodies, while action potentials occur only in axons. (D)</p> Signup and view all the answers

    What is the primary mechanism responsible for maintaining the concentration gradient of potassium ions across the cell membrane?

    <p>Active transport by the sodium-potassium pump (A)</p> Signup and view all the answers

    Which of the following statements accurately describes depolarization?

    <p>The membrane potential moves away from the resting potential towards a more positive value. (A)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of an action potential?

    <p>It can be depolarizing or hyperpolarizing. (A)</p> Signup and view all the answers

    What is the difference between graded potentials and action potentials?

    <p>Graded potentials are localized and decrease in strength over distance, while action potentials are propagated without decrement. (B)</p> Signup and view all the answers

    What is the significance of the threshold value in the generation of an action potential?

    <p>It determines the strength of the stimulus required to trigger an action potential. (B)</p> Signup and view all the answers

    What is the role of the sodium-potassium pump in maintaining the resting potential of a neuron?

    <p>It pumps sodium ions into the cell and potassium ions out of the cell. (A)</p> Signup and view all the answers

    Which type of ion channel is always open and plays a crucial role in maintaining the resting membrane potential?

    <p>Leak channels (A)</p> Signup and view all the answers

    What makes the sodium-potassium pump an electrogenic pump?

    <p>It involves the transport of charged molecules. (A)</p> Signup and view all the answers

    During the falling phase of an action potential:

    <p>Sodium channels are closed and potassium channels are open. (A)</p> Signup and view all the answers

    Which of the following scenarios would be most likely to lead to hyperpolarization of a neuron?

    <p>An increase in the permeability of the membrane to potassium ions. (C)</p> Signup and view all the answers

    How does the refractory period contribute to the propagation of an action potential?

    <p>It ensures that the action potential travels in only one direction. (A)</p> Signup and view all the answers

    What is the primary reason that saltatory conduction allows for fast transmission of action potentials?

    <p>Myelin insulation prevents current loss, allowing for a faster flow of ions. (D)</p> Signup and view all the answers

    What is the primary difference in action potential conduction between myelinated and unmyelinated axons?

    <p>Action potentials in myelinated axons jump between nodes, while in unmyelinated axons they travel continuously. (B)</p> Signup and view all the answers

    Which of the following is TRUE regarding the role of the axon hillock in myelinated axons?

    <p>The axon hillock is responsible for generating the action potential, and contributes to its rapid transmission down the axon. (D)</p> Signup and view all the answers

    What is the typical range of conduction velocities for myelinated axons in vertebrates?

    <p>Up to 100 m/s (A)</p> Signup and view all the answers

    Why might invertebrates generally have lower conduction velocities compared to vertebrates?

    <p>Invertebrates lack myelinated axons. (B)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the repolarization phase of the action potential?

    <p>Sodium ions continue to flow into the cell (C)</p> Signup and view all the answers

    What is the primary purpose of the refractory period?

    <p>To ensure that the action potential travels in one direction only. (B)</p> Signup and view all the answers

    How does the concentration of sodium voltage-gated channels at the axon hillock contribute to action potential initiation?

    <p>It reduces the threshold for depolarization, making it easier to initiate an action potential. (A)</p> Signup and view all the answers

    What is the role of potassium leak channels in maintaining the resting membrane potential?

    <p>They help to maintain a negative charge inside the cell by continuously allowing potassium ions to leak out. (C)</p> Signup and view all the answers

    How does the depolarization of one segment of an unmyelinated axon contribute to the initiation of an action potential in the adjacent segment?

    <p>The depolarization causes the sodium channels in the adjacent segment to open, leading to an influx of sodium ions. (A)</p> Signup and view all the answers

    How does myelination affect the conduction velocity of an action potential?

    <p>Myelination increases the conduction velocity by reducing the leakage of ions across the membrane. (C)</p> Signup and view all the answers

    Which of the following is TRUE about the propagation of action potentials in myelinated axons?

    <p>Action potentials only occur at the nodes of Ranvier, where the myelin sheath is absent. (D)</p> Signup and view all the answers

    What is the role of the sodium-potassium pump in restoring the resting membrane potential after an action potential?

    <p>It transports sodium ions out of the cell and potassium ions into the cell, re-establishing the concentration gradients for these ions that are necessary for the resting membrane potential. (D)</p> Signup and view all the answers

    Flashcards

    Nervous System

    A rapid system that coordinates body functions in animals, except sponges.

    Neuron

    An individual cell that transmits information in the nervous system.

    Synapse

    Connection between an axon terminal and an effector cell.

    Effector

    A cell that responds to commands from the nervous system, like muscle or gland cells.

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    Bioelectricity

    Electrical processes that occur at the neuronal membrane, crucial for signal transmission.

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    Na+/K+ ATPase

    Active transport pump that moves 3 Na+ out and 2 K+ in, maintaining ion gradients.

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    Resting Membrane Potential (RMP)

    The static electrical potential across a cell membrane, typically around -70 mV.

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    Electrogenic pump

    A pump that generates an electrical potential; Na+/K+ ATPase is one example.

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    Graded Potentials

    Changes in membrane potential due to ion permeability changes; small and variable shifts.

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    Leak Channels

    Ion channels that are always open, allowing continuous ion flow, such as K+ channels at rest.

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    Depolarization

    When the membrane potential becomes more positive inside, resulting in a reduced polarization.

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    Hyperpolarization

    An increase in membrane potential, making the inside more negative than resting potential.

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    Passive Diffusion of K+

    The movement of K+ ions out of the cell through open channels, driven by a chemical gradient.

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    Action Potential (AP) Rise Phase

    A rapid increase in membrane potential due to positive feedback from Na+ entering the neuron.

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    Refractory Period

    A phase following an action potential when a neuron cannot fire another AP, ensuring unidirectionality.

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    Propagation of Action Potential

    The process where an AP moves along an axon as ion flows depolarize the adjacent sections of the membrane.

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    AP Conduction in Unmyelinated Axon

    In unmyelinated axons, APs propagate by the local flow of ions that depolarize neighboring segments.

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    Axon Hillock

    The region where the axon begins, containing a high concentration of voltage-gated Na+ channels crucial for AP initiation.

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    Na+/K+ Pump

    A membrane protein that helps maintain RMP by pumping 3 Na+ out and 2 K+ in against their gradients.

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    Electrotonic potentials

    A type of graded potential that can depolarize or hyperpolarize.

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    Action potentials

    All-or-nothing signals initiated at the axon hillock.

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    Threshold value

    The membrane potential that must be reached to generate an action potential.

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    Voltage-gated channels

    Membrane proteins that open/close in response to changes in membrane potential.

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    Falling phase of AP

    The phase where K+ ions flow out, returning the membrane potential to resting state.

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    Ion currents

    Movement of ions (like Na+ and K+) through channels that affect membrane potential.

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    Axon Diameter

    Larger axon diameters result in faster conduction speeds, up to 40 m/s.

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    Saltatory Conduction

    In myelinated axons, action potentials jump between nodes, increasing speed.

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    Myelin Sheath

    A protective insulating layer around axons that prevents ion loss and speeds up conduction.

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    Node of Ranvier

    Gaps in the myelin sheath where ion exchanges occur, allowing saltatory conduction.

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    Action Potential Speed

    Speed of action potentials can reach up to 100 m/s in myelinated axons, particularly in vertebrates.

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    Potential

    Difference in electrical charge between regions measured in volts.

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    Current

    Flow of electrical charge between regions; opposite charges attract.

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    Membrane Potential

    Unequal charge distribution across a cell membrane.

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    Polarized Cells

    All living cells have a membrane potential; inside is negative relative to outside.

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    Excitable Cells

    Neurons and muscle cells with large membrane potentials and mechanisms to regulate them.

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    Electrotonic Potentials (EP)

    Local changes in membrane potential in response to stimuli.

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    Action Potentials (AP)

    Rapid changes in membrane potential that propagate along the cell.

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    Study Notes

    Animal Body Systems - Electrochemical Potentials in Neurons

    • Electrochemical potentials in neurons are crucial for communication and function.
    • All living cells are electrically polarized, meaning they have a membrane potential (MP).
    • The inside of the membrane is negative relative to the outside.
    • The size of the MP ranges from -10 to -90 mV.
    • Neurons and muscle cells are excitable cells, having large membrane potentials and specialized mechanisms to regulate.
    • Three significant types of membrane potentials include resting membrane potential, electrotonic potentials, and action potentials.
    • Membrane potentials and currents are reliant on inorganic ions.
    • All cells possess resting membrane potential, measured when inactive.
    • Unequal distribution of positive and negative charges across the membrane creates a potential difference (resting potential).
    • Key ions involved are sodium (Na⁺) and potassium (K⁺).

    Ion Concentrations in Cells

    • Extracellular fluid generally has high sodium (Na⁺) and low potassium (K⁺) concentrations.
    • Intracellular fluid usually has high potassium (K⁺) and low sodium (Na⁺) concentrations.
    • Specific concentrations, in millimoles (mM) vary:
      • Intracellular Na⁺: ~15 mM
      • Extracellular Na⁺: ~150 mM
      • Intracellular K⁺: ~150 mM
      • Extracellular K⁺: ~5 mM

    Ion Gradients in Cells

    • Ion gradients are maintained by active transport using the Na⁺/K⁺ ATPase pump.
    • This pump moves 3 sodium ions out of the cell and 2 potassium ions into the cell.
    • The pump is electrogenic, meaning it generates a small electrical potential.
    • A -10 mV potential is generated from ion gradients.
    • Anionic proteins, within the cell, contribute to a -5 mV potential.

    The Additional Potential in Neurons

    • The resting potential of neurons (-55 mV) arises primarily from passive diffusion of K+ through open K+ channels.
    • There's a chemical gradient for K+, but no electrical gradient.
    • Na+/K+ ATPase and leak channels together create an electrochemical gradient.

    Resting Potential of Neurons

    • Na+/K+ active transport pumps establish concentration gradients of Na+ and K+ across the membrane.
    • Open channels (leak channels) allow K+ ions to flow freely outward.
    • Negatively charged molecules (proteins) inside cannot cross the membrane.
    • Results in a resting membrane potential of -70 mV.

    Membrane Ion Channels

    • Channels are specific to each ion.
    • Leak channels are always open, e.g., K⁺ channel at rest.
    • Other channels are regulated (gated).
    • Voltage-gated channels are common in neurons.
    • Ion movement depends on the concentration gradient.

    Graded Potentials

    • Changes in membrane potential due to ion permeability are graded potentials.
    • Electrotonic potentials are a type of graded potential common in dendrites and cell bodies.

    Electrotonic Potentials

    • Current (ions) travels along the membrane surface, generating a small (mV) potential change.
    • Can depolarize or hyperpolarize.
    • Short distance travel.
    • Critical for initiating action potentials in the axon hillock.

    Action Potentials

    • Action potentials are rapid and large changes in membrane potential.
    • Transient and have an all-or-nothing characteristic.
    • Depolarizes the membrane (from -70 to +35 mV).
    • Initiated at the axon hillock and travel along the entire axon.
    • Rely on ion currents through voltage-gated ion channels.

    Generation of an Action Potential

    • Triggered when a stimulus pushes the resting potential to threshold.
    • Voltage-gated Na⁺ and K⁺ channels open and close in response to voltage changes.
    • Inward flow of Na⁺ changes the membrane potential to positive, and outward flow of K⁺ returns it to negative values.

    Depolarization

    • Action potentials depend on voltage-gated ion channels (Na⁺ and K⁺).
    • Na⁺, voltage-gated sodium channels open, causing rapid Na⁺ influx.
    • K⁺, voltage-gated potassium channels open, causing K⁺ efflux.

    The Rest of the Action Potential (Falling Phase)

    • K⁺ channels open more, leading to K⁺ efflux and repolarization (return to negative potential).
    • Na⁺ channels become inactivated; K⁺ channels close eventually.

    Propagation of Action Potentials

    • Action potentials move along axons as depolarization occurs in successive segments.

    AP Propagation Along Axon

    • Initiated at the axon hillock.
    • Movements are unchanged along the axon membrane towards terminals.
    • Dendrites and cell bodies have a concentration of K⁺ channels that reduce backward propagation.

    AP Conduction in Unmyelinated Axons

    • Threshold reduction occurs at the axon hillock.
    • Na⁺ concentration influences channel locations.
    • Currents spread along the membrane to create new action potentials.

    AP Conduction in Myelinated Axons - Saltatory Conduction

    • Myelin prevents ions from crossing the membrane (reduced current loss).
    • Na⁺ and K⁺ concentrations are high at nodes.
    • Currents leap between nodes resulting in faster conduction.

    The Hodgkin-Huxley Cycle

    • The rise phase of the action potential is positive feedback.
    • Further depolarization → opening of Na⁺ channels → increased Na⁺ flow → further depolarization.

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    Description

    Explore the fascinating world of electrochemical potentials in neurons, a crucial aspect for understanding their communication and function. This quiz covers topics like resting membrane potential, action potentials, and the roles of sodium and potassium ions. Test your knowledge on the fundamental principles governing neuronal activity!

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