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Questions and Answers
What does the first line of defense in the human body primarily consist of?
What does the first line of defense in the human body primarily consist of?
Which system is responsible for physical barriers in the defense mechanisms of the human body?
Which system is responsible for physical barriers in the defense mechanisms of the human body?
What type of immunity is associated with nonspecific defenses like inflammation and fever?
What type of immunity is associated with nonspecific defenses like inflammation and fever?
Which of the following is NOT part of the first line of defense in the human body?
Which of the following is NOT part of the first line of defense in the human body?
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What is the main purpose of the three lines of defense in the human body?
What is the main purpose of the three lines of defense in the human body?
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What is the function of phagocytes in the immune system?
What is the function of phagocytes in the immune system?
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Which type of immunity is passed down genetically from parents and ancestors?
Which type of immunity is passed down genetically from parents and ancestors?
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What do eosinophils do in the immune system?
What do eosinophils do in the immune system?
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What is the role of Natural Killer Cells in the immune system?
What is the role of Natural Killer Cells in the immune system?
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When is Acquired Immunity considered to be active?
When is Acquired Immunity considered to be active?
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Which type of immunity is obtained during fetal development through the mother's placenta?
Which type of immunity is obtained during fetal development through the mother's placenta?
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Which class of immunoglobulin is the only one that can cross the placenta to confer passive immunity on the fetus?
Which class of immunoglobulin is the only one that can cross the placenta to confer passive immunity on the fetus?
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What is the function of IgA in the body?
What is the function of IgA in the body?
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Which class of immunoglobulin promotes neutralization and crosslinking of antigens effectively in the complement system activation?
Which class of immunoglobulin promotes neutralization and crosslinking of antigens effectively in the complement system activation?
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What is the role of cells filled with keratin in the skin?
What is the role of cells filled with keratin in the skin?
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What is the primary function of IgE in the body?
What is the primary function of IgE in the body?
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What is the process of introducing an attenuated or weakened antigen in a susceptible host called?
What is the process of introducing an attenuated or weakened antigen in a susceptible host called?
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How do mucous membranes protect the body?
How do mucous membranes protect the body?
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What is the function of the hair in the nose as mentioned in the text?
What is the function of the hair in the nose as mentioned in the text?
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Which bodily fluid contains an enzyme called lysozyme that kills bacteria?
Which bodily fluid contains an enzyme called lysozyme that kills bacteria?
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What is the main function of cerumen (ear wax) as mentioned in the text?
What is the main function of cerumen (ear wax) as mentioned in the text?
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When do cells play a role in inhibiting or destroying a pathogen according to the text?
When do cells play a role in inhibiting or destroying a pathogen according to the text?
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Study Notes
Defenses of the Human Body
- The human body has developed defense mechanisms to cope with constant attacks from microorganisms.
- There are three lines of defense: physical barriers, defensive cells and proteins, and the immune system.
First Line of Defense
- Physical barriers:
- Skin: cells filled with keratin make it impenetrable, waterproof, and resistant to toxins.
- Dead skin cells are shed and replaced, taking microbes with them.
- Mucous membranes:
- Line internal surfaces of respiratory, digestive, urinary, and reproductive systems.
- Produce mucous that traps microbes.
- Hair in the nose acts as a coarse filter.
- Chemical barriers:
- Sweat: washes away microbes and slows bacterial growth due to acidity.
- Mucous membranes: produce sticky mucous that traps microbes.
- Saliva and tears: contain lysozyme, an enzyme that kills bacteria by rupturing cell walls.
- Cerumen (ear wax): traps dirt and dust particles in the ear canal.
Second Line of Defense
- Defensive cells and proteins:
- Phagocytes (e.g., neutrophils, macrophages) engulf pathogens, damaged tissues, or dead cells.
- Eosinophils discharge destructive enzymes to destroy pathogens too big for phagocytes.
- Natural killer cells seek out and destroy abnormal cells (e.g., cancer cells).
- Inflammation and fever: nonspecific responses to infection.
Immunity
- Types of immunity:
- Inborn immunity: genetic predisposition received from parents and ancestors.
- Acquired immunity: obtained through exposure to antigens, either naturally or artificially.
Acquired Immunity
- Active acquired immunity: obtained once a person comes into direct contact with a disease, providing permanent immunity.
- Passive acquired immunity:
- Naturally acquired: occurs when a person is exposed to a disease, providing temporary immunity.
- Artificially acquired: introduced through a vaccine, which stimulates antibody production.
Antibodies (Immunoglobulins)
- Types of immunoglobulins:
- IgG: most abundant in blood, promotes opsonization, neutralization, and cross-linking of antigens.
- IgA: found in secretions (e.g., tears, saliva, mucus, breast milk), provides localized defense of mucous membranes.
- IgM: first antibody produced after initial exposure to an antigen, effective in complement system activation.
- IgE: triggers release of histamine and other chemicals that cause allergic reactions.
- IgD: acts as an antigen receptor in B cells, stimulating proliferation and differentiation.
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Description
Learn about animal defense responses in the context of Chapter 3 on Animal and Plant Defense Responses. Explore the defenses of the human body, types of immunity and antibodies, and the importance of body defense responses through investigation.