Angina Treatment: Nitrates and Beta Blockers

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6 Questions

What is the mechanism of action of nitrates in reducing angina attacks?

Vasodilation, reducing preload and myocardial oxygen demand

Which of the following medications is an example of a potassium channel opener?

Nicorandil

What is the mechanism of action of beta blockers in reducing angina attacks?

Reducing heart rate and blood pressure, decreasing myocardial oxygen demand

Which of the following medications is used to prevent thrombus formation and reduce the risk of acute coronary syndrome?

Aspirin

What is the mechanism of action of calcium channel blockers in reducing angina attacks?

Vasodilation, reducing myocardial oxygen demand

Which of the following medications is used to reduce cholesterol levels and prevent progression of atherosclerosis?

Atorvastatin

Study Notes

Nitrates

  • Used to reduce frequency and severity of angina attacks
  • Mechanism of action: vasodilation, reducing preload and myocardial oxygen demand
  • Examples:
    • Glyceryl trinitrate (GTN)
    • Isosorbide mononitrate (ISMN)
    • Isosorbide dinitrate (ISDN)

Beta Blockers

  • Used to reduce frequency and severity of angina attacks
  • Mechanism of action: reducing heart rate and blood pressure, decreasing myocardial oxygen demand
  • Examples:
    • Atenolol
    • Metoprolol
    • Propranolol

Calcium Channel Blockers

  • Used to reduce frequency and severity of angina attacks
  • Mechanism of action: vasodilation, reducing myocardial oxygen demand
  • Examples:
    • Amlodipine
    • Felodipine
    • Verapamil

Potassium Channel Openers

  • Used to reduce frequency and severity of angina attacks
  • Mechanism of action: vasodilation, reducing myocardial oxygen demand
  • Examples:
    • Nicorandil

Ranolazine

  • Used to reduce frequency and severity of angina attacks
  • Mechanism of action: reducing late sodium current, decreasing myocardial oxygen demand
  • Example:
    • Ranolazine

Anti-Platelet Agents

  • Used to prevent thrombus formation and reduce risk of acute coronary syndrome
  • Examples:
    • Aspirin
    • Clopidogrel

Statins

  • Used to reduce cholesterol levels and prevent progression of atherosclerosis
  • Examples:
    • Atorvastatin
    • Simvastatin

Angina Medications

  • Nitrates are used to reduce frequency and severity of angina attacks by vasodilation, reducing preload and myocardial oxygen demand
  • Examples of nitrates include Glyceryl trinitrate (GTN), Isosorbide mononitrate (ISMN), and Isosorbide dinitrate (ISDN)

Beta Blockers

  • Beta blockers reduce frequency and severity of angina attacks by reducing heart rate and blood pressure, decreasing myocardial oxygen demand
  • Examples of beta blockers include Atenolol, Metoprolol, and Propranolol

Calcium Channel Blockers

  • Calcium channel blockers reduce frequency and severity of angina attacks by vasodilation, reducing myocardial oxygen demand
  • Examples of calcium channel blockers include Amlodipine, Felodipine, and Verapamil

Potassium Channel Openers

  • Potassium channel openers reduce frequency and severity of angina attacks by vasodilation, reducing myocardial oxygen demand
  • Nicorandil is an example of a potassium channel opener

Ranolazine

  • Ranolazine reduces frequency and severity of angina attacks by reducing late sodium current, decreasing myocardial oxygen demand
  • Ranolazine is an example of this type of medication

Anti-Platelet Agents

  • Anti-platelet agents prevent thrombus formation and reduce risk of acute coronary syndrome
  • Examples of anti-platelet agents include Aspirin and Clopidogrel

Statins

  • Statins reduce cholesterol levels and prevent progression of atherosclerosis
  • Examples of statins include Atorvastatin and Simvastatin

Learn about the medications used to treat angina attacks, including nitrates and beta blockers, their mechanisms of action, and examples of each.

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