Anesthesia and Preanesthetic Medication

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Questions and Answers

What is the primary aim of administering benzodiazepines before general anesthesia?

  • To hasten gastric emptying
  • To prevent vagal bradycardia
  • To reduce anxiety and apprehension (correct)
  • To relieve postoperative pain

Which drug class is preferred to prevent vagal bradycardia while minimizing CNS effects?

  • Benzodiazepines
  • Opioid analgesics
  • Antimuscarinic agents (correct)
  • Hâ‚‚-blockers

What is a potential side effect of opioid analgesics when used as preanaesthetic medication?

  • Laryngospasm
  • Reduced gastric emptying
  • Increased salivary secretions
  • Nausea and vomiting (correct)

Which medication class is used to expedite gastric emptying before emergency surgery?

<p>Prokinetic drugs (B)</p> Signup and view all the answers

What defines conscious sedation in a clinical setting?

<p>The ability to communicate and cooperate (D)</p> Signup and view all the answers

Flashcards

Conscious Sedation

A state of CNS depression where patients remain conscious but relaxed, allowing them to cooperate and communicate during procedures.

Preanaesthetic Medication

A type of medication given before anesthesia to reduce anxiety, prevent complications like bradycardia, and prepare for surgery.

Benzodiazepines (BZDs)

A class of drugs commonly used for preanaesthetic medication to reduce anxiety and apprehension.

Hâ‚‚-blockers and Proton-Pump Inhibitors

Medications used to prevent the buildup of stomach acid and ulcers, often given before prolonged surgeries.

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Antiemetics

Drugs used to prevent vomiting, especially when given preanaesthetically.

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Study Notes

Preanaesthetic Medication

  • Used to make anesthesia more pleasant and safe
  • Aims to reduce anxiety and apprehension
  • Benzodiazepines (BZDs) like diazepam, lorazepam, or midazolam are preferred due to sedative, amnesic, calming, and anxiolytic effects, and wide safety margins
  • Act on the limbic system to reduce anxiety

Preventing Vagal Bradycardia and Reducing Salivary Secretions

  • Antimuscarinic agents like atropine or glycopyrrolate used to prevent vagal bradycardia and hypotension
  • Glycopyrrolate is preferred due to its potency, lack of significant CNS effects, and less tachycardia

Relieving Pain

  • Opioid analgesics like morphine, pethidine, or fentanyl used to relieve pre- and postoperative pain
  • Limitations include respiratory depression, hypotension, nausea, vomiting, constipation, biliary spasm, and bronchospasm in asthmatics
  • NSAIDs like diclofenac can also be used

Antiemetic Effects

  • Metoclopramide, domperidone, or ondansetron used to control vomiting

Preventing Acid Secretion and Stress Ulcers

  • H2-blockers like ranitidine and proton-pump inhibitors like omeprazole used to reduce gastric acid secretion, especially before long surgeries

Hastening Gastric Emptying

  • Metoclopramide or domperidone used to increase lower esophageal sphincter tone and accelerate gastric emptying, preventing aspiration pneumonia
  • These are prokinetic drugs

Conscious Sedation

  • Level of CNS depression where patients do not lose consciousness but can communicate and cooperate during procedures/treatment
  • Indications include uncooperative and anxious patients

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