Anemia: Types and Causes

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Questions and Answers

What is the main cause of microcytic hypochromic anemia?

  • Pregnancy
  • Deficiency in iron (correct)
  • Chronic blood loss
  • Massive hemorrhage

Which symptom is NOT associated with iron deficiency anemia?

  • Cold hands and feet
  • Headache, lightheadedness, dizziness
  • Sore or inflamed, swollen tongue (correct)
  • Restless leg syndrome

What is indicative of megaloblastic anemia?

  • Iron deficiency
  • Normal bone marrow
  • Failure to make sufficient number of normal erythrocytes
  • Enlarged cells and nuclei (correct)

Who is more commonly affected by iron insufficiency anemia?

<p>Women (B)</p> Signup and view all the answers

What is the primary difference between the normal erythrocytes and those deficient in iron and hemoglobin?

<p>Microcytic and hypochromic characteristics (A)</p> Signup and view all the answers

What is the main function of ferritin in iron storage?

<p>To oxidize iron to Fe3+ and store it in a mineral form (B)</p> Signup and view all the answers

Which organelle is involved in the release of iron from ferritin?

<p>Lysosomes (C)</p> Signup and view all the answers

What happens to partially denatured ferritin when iron stores are high?

<p>It is called hemosiderin (B)</p> Signup and view all the answers

What is the normal range for blood ferritin in women?

<p>11 to 307 micrograms per liter (B)</p> Signup and view all the answers

What is the basic iron storage unit in ferritin?

<p>(FeO(OH)) with some FeO(H2PO4) (D)</p> Signup and view all the answers

What is the main function of hepcidin in the body?

<p>To inhibit the iron exporter ferroportin in various body tissues (B)</p> Signup and view all the answers

What effect does increased hepcidin levels have on iron supply during some infections and cancers?

<p>It restricts iron supply, thereby limiting bacterial growth (B)</p> Signup and view all the answers

How does hepcidin affect iron absorption from the diet?

<p>It decreases dietary iron absorption by blocking ferroportin (D)</p> Signup and view all the answers

What regulates hepcidin at the transcriptional level?

<p>High levels of intracellular iron (B)</p> Signup and view all the answers

In which cells does hepcidin block the iron exporter ferroportin?

<p>Intestinal enterocytes and macrophages (A)</p> Signup and view all the answers

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