Podcast
Questions and Answers
Which structure encapsulates the blood filtering system of the kidney?
Which structure encapsulates the blood filtering system of the kidney?
- Bowman's capsule (correct)
- Glomerulus
- Distal convoluted tubule
- Renal tubule
What role does the juxtaglomerular apparatus play in the kidney?
What role does the juxtaglomerular apparatus play in the kidney?
- Filters blood in the renal capsule
- Secretes anti-diuretic hormone
- Produces urine directly
- Regulates the function of each nephron (correct)
What happens when systemic blood pressure decreases?
What happens when systemic blood pressure decreases?
- Juxtaglomerular cells are stretched more
- Renin secretion stops completely
- Filtration in the glomerulus increases
- Juxtaglomerular cells release more renin (correct)
In which parts of the nephron does reabsorption primarily occur?
In which parts of the nephron does reabsorption primarily occur?
Which hormones are secreted to help maintain fluid and electrolyte balance in the kidneys?
Which hormones are secreted to help maintain fluid and electrolyte balance in the kidneys?
What primarily occurs in the distal convoluted tubule?
What primarily occurs in the distal convoluted tubule?
What is the normal serum creatinine level range for adult females?
What is the normal serum creatinine level range for adult females?
Which factor has the least effect on serum creatinine levels?
Which factor has the least effect on serum creatinine levels?
What indicates a decline in renal function when assessing creatinine levels?
What indicates a decline in renal function when assessing creatinine levels?
Why is urine osmolality testing preferred over specific gravity?
Why is urine osmolality testing preferred over specific gravity?
What is considered a normal Prostatic-Specific Antigen (PSA) level?
What is considered a normal Prostatic-Specific Antigen (PSA) level?
Which condition can cause an elevation in PSA levels?
Which condition can cause an elevation in PSA levels?
What should be avoided during the creatinine clearance testing period?
What should be avoided during the creatinine clearance testing period?
What does urine osmolality help to determine regarding kidney function?
What does urine osmolality help to determine regarding kidney function?
Creatinine is a byproduct of which physiological process?
Creatinine is a byproduct of which physiological process?
Which option correctly describes creatinine clearance?
Which option correctly describes creatinine clearance?
What is crucial to monitor after a procedure involving renal angiography?
What is crucial to monitor after a procedure involving renal angiography?
Post-procedure care for a patient who has undergone a biopsy involves:
Post-procedure care for a patient who has undergone a biopsy involves:
Which statement regarding nephroscopy is accurate?
Which statement regarding nephroscopy is accurate?
What is the primary function of the kidneys?
What is the primary function of the kidneys?
Which part of the kidney serves as the outer covering made of strong connective tissue?
Which part of the kidney serves as the outer covering made of strong connective tissue?
Where does urine drain after passing through the papillae?
Where does urine drain after passing through the papillae?
What is the functional unit of the kidney called?
What is the functional unit of the kidney called?
What condition is indicated by the presence of ketone bodies in urine?
What condition is indicated by the presence of ketone bodies in urine?
What does an increase in urine specific gravity generally indicate?
What does an increase in urine specific gravity generally indicate?
What is the normal range for blood urea nitrogen (BUN)?
What is the normal range for blood urea nitrogen (BUN)?
Which substance's presence in urine indicates urinary tract infection?
Which substance's presence in urine indicates urinary tract infection?
What is a condition that may lead to hematuria?
What is a condition that may lead to hematuria?
What does a high blood urea nitrogen (BUN) level indicate?
What does a high blood urea nitrogen (BUN) level indicate?
What is one of the main roles of serum creatinine tests?
What is one of the main roles of serum creatinine tests?
What can decreased urine specific gravity indicate?
What can decreased urine specific gravity indicate?
What is the primary function of the ureters in the urinary system?
What is the primary function of the ureters in the urinary system?
What changes occur in the urinary system of older adults?
What changes occur in the urinary system of older adults?
What is the primary function of the kidneys related to blood?
What is the primary function of the kidneys related to blood?
What is a common cause of urinary frequency and urgency in older adults?
What is a common cause of urinary frequency and urgency in older adults?
Which part of the kidney contains the renal tubules?
Which part of the kidney contains the renal tubules?
What can lead to an increased risk of urinary tract infections in older adults?
What can lead to an increased risk of urinary tract infections in older adults?
Which structure serves as the functional unit of the kidney?
Which structure serves as the functional unit of the kidney?
What is the function of papillae in the renal medulla?
What is the function of papillae in the renal medulla?
How do the kidneys respond to low oxygen levels in body tissues?
How do the kidneys respond to low oxygen levels in body tissues?
Flashcards
What is a nephron?
What is a nephron?
The functional unit of the kidney responsible for filtering blood and producing urine.
What is a glomerulus?
What is a glomerulus?
A tightly bound network of capillaries within the renal corpuscle where blood is filtered.
What is the renal cortex?
What is the renal cortex?
The outer layer of the kidney, containing millions of renal tubules.
What is the renal medulla?
What is the renal medulla?
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What are the three main functions of the nephron?
What are the three main functions of the nephron?
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What is a calyx?
What is a calyx?
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What is the hilus of the kidney?
What is the hilus of the kidney?
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Renal Angiography
Renal Angiography
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Brush Biopsy
Brush Biopsy
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Cystoscopy
Cystoscopy
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Nephroscopy
Nephroscopy
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Renal Venography
Renal Venography
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Hematuria
Hematuria
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Renal Calculus
Renal Calculus
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Ketoaciduria (Ketonuria)
Ketoaciduria (Ketonuria)
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Leukocytes in Urine
Leukocytes in Urine
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Urine Specific Gravity
Urine Specific Gravity
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Blood Urea Nitrogen (BUN)
Blood Urea Nitrogen (BUN)
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Serum Creatinine
Serum Creatinine
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Glomerulonephritis
Glomerulonephritis
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Pyelonephritis
Pyelonephritis
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Acute Tubular Necrosis
Acute Tubular Necrosis
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Glomerular Filtration Rate Control
Glomerular Filtration Rate Control
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Bowman's Capsule
Bowman's Capsule
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Renal Tubule
Renal Tubule
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Reabsorption
Reabsorption
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Secretion
Secretion
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Juxtaglomerular Apparatus (JGA)
Juxtaglomerular Apparatus (JGA)
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Renin
Renin
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Collecting Duct
Collecting Duct
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Stages of Urine Formation
Stages of Urine Formation
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What is creatinine?
What is creatinine?
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Why is creatinine a better indicator of kidney function than BUN?
Why is creatinine a better indicator of kidney function than BUN?
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What's the normal range for creatinine?
What's the normal range for creatinine?
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What is creatinine clearance?
What is creatinine clearance?
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What is the patient's role in creatinine clearance testing?
What is the patient's role in creatinine clearance testing?
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What do abnormal creatinine levels indicate?
What do abnormal creatinine levels indicate?
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What is PSA?
What is PSA?
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Why is PSA important?
Why is PSA important?
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What can lead to elevated PSA levels?
What can lead to elevated PSA levels?
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What does urine osmolality tell us?
What does urine osmolality tell us?
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What are the main tasks of a nephron?
What are the main tasks of a nephron?
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What are ureters and what is their function?
What are ureters and what is their function?
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What is the bladder and what's its role in the urinary system?
What is the bladder and what's its role in the urinary system?
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What is the urethra and what does it do?
What is the urethra and what does it do?
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What are some normal changes to the urinary system as we age?
What are some normal changes to the urinary system as we age?
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What are common urinary problems in older adults?
What are common urinary problems in older adults?
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Study Notes
Anatomy of the Urinary System
- The urinary system is crucial for homeostasis, maintaining balance in the body.
- It comprises two kidneys, two ureters, a bladder, and a urethra.
- Kidneys remove waste, excess water, and electrolytes from the blood, concentrating them into urine, and secrete erythropoietin to stimulate red blood cell production.
- Kidneys are located behind the parietal peritoneum, roughly 4-5 inches (10-12 cm) long, 2-3 inches (5-7.5 cm) wide, and 1 inch (2.5 cm) thick.
- The right kidney is lower than the left due to the liver's position.
- Each kidney is surrounded by adipose tissue.
- The hilus, a notch near the kidney's center, is where the ureter, blood vessels, and nerves enter and exit.
Gross Anatomy of the Kidney
- The renal capsule, a strong connective tissue covering, surrounds the kidney.
- The renal cortex lies just beneath the capsule and contains 1.25 million renal tubules.
- The renal medulla is deeper and darker in color, containing triangular pyramids.
- Urine drains from the pyramid papillae into the calyces.
- Calyces drain into the renal pelvis, which is the upper extension of the ureters.
- Ureters carry urine to the bladder, which expels urine via the urethra.
Microscopic Structure of the Kidney
- The nephron is the functional unit of the kidney, with over one million per kidney.
- Nephrons filter blood and process urine.
- Nephrons have three major functions.
Urine Formation
- Filtration of water and blood products occurs in the glomerulus of Bowman's capsule.
- Reabsorption of water, glucose, and necessary ions back into the bloodstream occurs mainly in the proximal convoluted tubules, Henle's loop, and the distal convoluted tubules.
- Secretion of certain ions, waste products, and drugs primarily takes place in the distal convoluted tubule.
Urine Composition and Characteristics
- Urine is mostly water (95%) with the remainder being nitrogenous waste and salts.
- Normal urine color is yellow due to urochrome.
- Urine maintains a consistent pH and electrolyte balance.
- Urine excretion helps regulate blood pressure and maintain homeostasis.
Other Urinary System Components
- Ureters transport urine from the kidneys to the bladder.
- The bladder stores urine and expels it via the urethra.
- With aging, kidneys lose function, blood supply decreases, and nephron numbers diminish.
- Potential incontinence issues may arise with aging for both men and women, particularly in the form of stress incontinence for women and constriction of the urethra due to an enlarged prostate in men.
Urine Tests
- Routine urinalysis: examination of urine's physical and chemical characterstics to detect medical issues, including color, clarity, odor, pH, specific gravity, and presence of substances like glucose, protein, ketones, red blood cells, and white blood cells.
- 24-hour urine: measuring excreted substances over 24 hours for a comprehensive evaluation of kidney function, including protein, creatinine, urea, uric acid, and catecholamines (Epinephrine and Norepinephrine).
- Blood urea nitrogen (BUN) and serum creatinine measurements assess kidney function, and normal ranges are provided.
Other Diagnostic Procedures
- Renal angiography—evaluates blood supply to the kidneys, assesses masses, and detects potential transplant complications.
- Intravenous pyelography (IVP)—evaluates the urinary tract using contrast dye to visualize the renal pelvis, ureters, and bladder.
- Computed tomography scan (CT)—creates detailed images of the kidneys, bladder, and other organs, often including the structures in a cross-sectional view.
- Magnetic resonance imaging (MRI)—produces detailed anatomical images of the urinary system, often used for more in-depth evaluations.
- Ultrasonography—employs sound waves to create images of internal structures, often used for initial evaluation of the urinary tract.
- Cystoscopy—uses a scope to view the urinary bladder and urethra for diagnosis or treatment, often allowing biopsies or other procedures to be performed.
- Retrograde pyelography—injects contrast dye to visualize the upper urinary tract (including ureters and renal pelvis).
- Voiding cystourethrography—evaluates the bladder and urethra using contrast dye to assess for infections or structure problems during urination.
- Urodynamic studies—assesses bladder muscle activity and the flow of urine, often used to evaluate incontinence.
- Renal scan—a series of images to examine the kidneys and their blood supply.
- Transrectal ultrasound—used to visualize and evaluate the prostate gland.
- Renal Biopsy—a procedure in the assessment for diseases and complications impacting the kidneys
- Procedures using contrast material should have patient preparation (NPO) and consideration of allergies to iodine or contrast agents.
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