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Questions and Answers
What is the posterior boundary of the anterior mediastinum?
What is the posterior boundary of the anterior mediastinum?
Which structure is NOT found in the middle mediastinum?
Which structure is NOT found in the middle mediastinum?
Which of the following is a component of the posterior mediastinum?
Which of the following is a component of the posterior mediastinum?
What is the inferior boundary of the middle mediastinum?
What is the inferior boundary of the middle mediastinum?
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Which vein is formed at the root of the neck by the union of the right subclavian and the right internal jugular veins?
Which vein is formed at the root of the neck by the union of the right subclavian and the right internal jugular veins?
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Which structure lies anterior to the left brachiocephalic vein?
Which structure lies anterior to the left brachiocephalic vein?
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Which lymph nodes are specifically mentioned in relation to the posterior mediastinum?
Which lymph nodes are specifically mentioned in relation to the posterior mediastinum?
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What connects the body of the sternum to the fibrous pericardium?
What connects the body of the sternum to the fibrous pericardium?
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What is the function of the thyroid ima artery?
What is the function of the thyroid ima artery?
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Where does the left common carotid artery originate from?
Where does the left common carotid artery originate from?
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What major region does the left subclavian artery supply?
What major region does the left subclavian artery supply?
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At which vertebral level does the descending thoracic aorta begin?
At which vertebral level does the descending thoracic aorta begin?
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Which arteries branch off the descending thoracic aorta?
Which arteries branch off the descending thoracic aorta?
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Where does the pulmonary trunk terminate?
Where does the pulmonary trunk terminate?
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What type of blood does the pulmonary trunk carry?
What type of blood does the pulmonary trunk carry?
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Which artery runs alongside and supplies organs such as the esophagus and bronchial tissue?
Which artery runs alongside and supplies organs such as the esophagus and bronchial tissue?
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What structures drain into the right brachiocephalic vein?
What structures drain into the right brachiocephalic vein?
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What is the main function of the superior vena cava?
What is the main function of the superior vena cava?
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At what anatomical location does the superior vena cava begin?
At what anatomical location does the superior vena cava begin?
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Which veins drain into the left brachiocephalic vein?
Which veins drain into the left brachiocephalic vein?
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Where does the superior vena cava enter the pericardium?
Where does the superior vena cava enter the pericardium?
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What is one use of large systemic veins in clinical procedures?
What is one use of large systemic veins in clinical procedures?
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Which veins comprise the azygos venous system?
Which veins comprise the azygos venous system?
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What anatomical structure does the azygos vein primarily drain into?
What anatomical structure does the azygos vein primarily drain into?
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What is the primary developmental role of the thymus?
What is the primary developmental role of the thymus?
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What happens to the thymus after puberty?
What happens to the thymus after puberty?
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Which arteries supply blood to the thymus?
Which arteries supply blood to the thymus?
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What is the typical venous drainage for the thymus?
What is the typical venous drainage for the thymus?
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Where does lymphatic drainage from the thymus return?
Where does lymphatic drainage from the thymus return?
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What is a clinical correlation associated with the thymus?
What is a clinical correlation associated with the thymus?
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What kind of innervation do the vagus nerves provide to the thoracic viscera?
What kind of innervation do the vagus nerves provide to the thoracic viscera?
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How do visceral afferents in the vagus nerves function regarding pain sensation?
How do visceral afferents in the vagus nerves function regarding pain sensation?
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What is the primary function of the right phrenic nerve as it descends in the middle mediastinum?
What is the primary function of the right phrenic nerve as it descends in the middle mediastinum?
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Where does the left phrenic nerve pierce the diaphragm?
Where does the left phrenic nerve pierce the diaphragm?
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Which lymph nodes receive drainage from the skin of the anterior thoracic wall?
Which lymph nodes receive drainage from the skin of the anterior thoracic wall?
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What drains into the thoracic duct from the posterior intercostal nodes?
What drains into the thoracic duct from the posterior intercostal nodes?
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Which structure lies adjacent and slightly posterior to the left brachiocephalic vein?
Which structure lies adjacent and slightly posterior to the left brachiocephalic vein?
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What is true about the intercostal nodes in the upper thorax?
What is true about the intercostal nodes in the upper thorax?
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Which node group collects lymph from the deep vessels of the anterior intercostal spaces?
Which node group collects lymph from the deep vessels of the anterior intercostal spaces?
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The diaphragmatic nodes are primarily located where?
The diaphragmatic nodes are primarily located where?
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Where are the connector cells of the parasympathetic system primarily located?
Where are the connector cells of the parasympathetic system primarily located?
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How many ganglia are present in the thoracic part of the sympathetic trunk?
How many ganglia are present in the thoracic part of the sympathetic trunk?
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What structure does the thoracic part of the sympathetic trunk pass behind to leave the thorax?
What structure does the thoracic part of the sympathetic trunk pass behind to leave the thorax?
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What is the first ganglion of the thoracic sympathetic trunk often fused with?
What is the first ganglion of the thoracic sympathetic trunk often fused with?
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What is the primary function of the gray rami communicantes in the thoracic sympathetic trunk?
What is the primary function of the gray rami communicantes in the thoracic sympathetic trunk?
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Which structures receive postganglionic fibers from the first five ganglia of the thoracic sympathetic trunk?
Which structures receive postganglionic fibers from the first five ganglia of the thoracic sympathetic trunk?
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What characterizes the lower eight ganglia of the thoracic sympathetic trunk?
What characterizes the lower eight ganglia of the thoracic sympathetic trunk?
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Study Notes
Mediastinum
- The mediastinum is a thick midline partition between the two lungs
- It extends anteriorly to the sternum and posteriorly to the vertebral column
- It extends from the superior thoracic aperture to the diaphragm
- It contains the remains of the thymus, the heart and major blood vessels, the trachea and esophagus, the thoracic duct and lymph nodes, the vagus and phrenic nerves, and the sympathetic trunks
- The mediastinum is divided into superior and inferior mediastina by an imaginary plane passing through the sternal angle, through T4 and T5
- The inferior mediastinum is further divided into middle, anterior, and posterior mediastinum
- The middle mediastinum contains the pericardium and heart
- The anterior mediastinum is the space between the sternum and pericardium
- The posterior mediastinum is the space between the pericardium and the spinal column
Superior Mediastinum
- Contains the thymus, major blood vessels (superior vena cava, aortic arch, brachiocephalic veins), trachea, esophagus, thoracic duct, and sympathetic trunks.
- Boundaries: anteriorly by the manubrium sterni, posteriorly by vertebrae T1-T4, superiorly by the superior thoracic aperture, inferiorly by a plane passing through the sternal angle and T4/T5
Inferior Mediastinum
- Contains the heart within the pericardium, phrenic nerves on each side, esophagus and thoracic duct, descending aorta, and sympathetic trunks.
- Subdivisions: anterior, middle, and posterior mediastina.
Anterior Mediastinum
- Located between the sternum and pericardium.
- Contains connective tissue, fat, and remnants of the thymus
- Boundaries: anteriorly by the body of the sternum and the transverse thoracic muscle, posteriorly by the pericardium, superiorly by a line between the sternal angle and T4, and inferiorly by the diaphragm
Middle Mediastinum
- Contains the heart and pericardial sac.
- Also contains the roots of the great vessels—the ascending aorta, superior vena cava, pulmonary trunk, pulmonary veins—and the phrenic nerves.
Posterior Mediastinum
- Lies between the pericardium and the vertebral column.
- Contains the descending thoracic aorta, the thoracic duct, posterior intercostal vessels, azygos and hemiazygos veins, esophagus, and esophageal plexus, sympathetic trunks and splanchnic nerves.
- Boundaries: anteriorly by the pericardium and the diaphragm, posteriorly by the vertebral bodies, superiorly by the level of the sternal angle and T4, and inferiorly by the diaphragm
Azygos Vein
- Consists of the main azygos vein, the inferior hemiazygos, and the superior hemiazygos veins
- Drains blood from the posterior parts of the intercostal spaces, posterior abdominal wall, pericardium, diaphragm and esophagus.
- Azygos vein forms at the level of the right side of the L1 and L2 vertebrae.
Superior Hemiazygos Vein
- Fornmed by the union of the fourth to eighth intercostal veins and occasionally left bronchial veins
- It joins the azygos vein at the level of the seventh or eighth thoracic vertebrae.
- Often connected to the left superior intercostal vein.
Inferior Hemiazygos Vein
- Usually formed by the union of the left ascending lumbar vein and left subcostal vein, but may arise from either vein alone.
- Ascends the left side of the thoracic cavity, turning posterior to the thoracic duct, aorta and esophageal.
Thoracic Aorta
- The descending thoracic aorta is a continuation of the aortic arch that extends down the posterior thoracic cavity
- It provides branches for the posterior intercostal spaces, subcoastal spaces, and pericardial, esophageal, and broncial arteries.
Pulmonary Trunk
- Carries deoxygenated blood from the right ventricle of the heart into the lungs
- It is roughly 2 inches in length and descends to the left. It is divided into the right and left pulmonary artery
- Enclosed in the fibrous pericardium, together with the ascending aorta
The Autonomic Nervous System
- The autonomic nervous system is responsible for controlling involuntary bodily functions such as heart rate, blood pressure, digestion, and pupil dilation
- Divided into two parts: sympathetic and parasympathetic, both with afferent and efferent nerve fibers
- The sympathetic division prepares the body for stress or emergency, resulting in increased heart rate and blood pressure, while the parasympathetic division promotes rest and digestion
Phrenic Nerves
- Originate in the cervical spine, typically C3-C5.
- Descend into the thorax, passing lateral to the vagus nerve and posterior to the origin of the brachiocephalic vein
- Provide motor innervation to the diaphragm and sensory innervation to the diaphragm, pericardium, and pleura
Clinical Correlation
- Several types of diseases can occur in the thoracic cavity and its structures. Understanding the structures and their function is crucial for diagnosis and treatment
Lymphatic Drainage of the Esophagus
- The lymphatic vessels in the superior third of the esophagus drain to the deep cervical lymph nodes
- The vessels in the middle third drain to superior and posterior mediastinal lymph nodes
- Vessels in the inferior third drain to lymph nodes surrounding the left gastric vessels and the celiac nodes
Lymph Nodes and Vessels of the Thorax
- The lymph vessels from the superficial regions of the anterior thoracic wall drain into superior axillary lymph nodes
- The lymph vessels from the superficial regions of the posterior thoracic wall drain into posterior axillary lymph nodes
Right Lymphatic Duct
- Collects lymph from the right side of the head, neck, right upper limb, and right side of the thorax
- Enters the right brachiocephalic vein
Thoracic Duct
- Collects lymph from the majority of the body below the diaphragm, left side of the thorax, and the left upper limb
- Enters the left brachiocephalic vein
Thymus
- Located in the superior mediastinum, posterior to the sternum and anterior to the pericardium
- Develops and grows until puberty, then undergoes involution
Esophagus
- A muscular tube begins at the level of the cricoid cartilage(C6) at the end of the pharynx and ends at the cardiac orifice of the stomach at the level of the 10th thoracic vertebra reaching the level of T11
- It’s the narrowest part of the GIT after the pylorus and appendix
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Test your knowledge on the structures and boundaries of the mediastinum, including anterior, middle, and posterior components. This quiz covers arteries, veins, and lymph nodes associated with the mediastinum. Perfect for students studying human anatomy and physiology.