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Ch 8: The structural and functional unit of the kidney

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What is the structural and functional unit of the kidney?

Renal corpuscle

Which arteriole brings blood into the glomerulus?

Afferent arteriole

What is the function of the efferent arteriole in the nephron?

Carries blood away from the glomerulus

What is the role of autoregulation in kidney function?

Regulates glomerular filtration rate

How does tubuloglomerular feedback (TGF) regulate GFR in the nephron?

Via changes in tubular fluid flow and composition

What parameter is used to assess kidney function?

Glomerular filtration rate (GFR)

How does the unique arrangement of arterioles contribute to kidney function?

Regulates blood flow within the nephron

What is the role of the afferent arteriole in response to increased sodium levels in the tubular fluid?

Constricts to reduce blood flow into the glomerulus

Which hormone is released by the juxtaglomerular cells in response to low blood pressure or decreased sodium levels?

Renin

How does Angiotensin II influence blood pressure?

Stimulates vasoconstriction of arterioles

Which of the following hormones promotes sodium reabsorption in the renal tubules?

Aldosterone

In response to increased blood volume and pressure, which action does Atrial Natriuretic Peptide (ANP) promote?

Dilating the afferent arterioles

What is the primary effect of the kidneys in regulating acid-base balance?

Reabsorbing bicarbonate ions

Which component of the nephron is crucial for maintaining physiological balance and health?

Juxtaglomerular apparatus

How do the kidneys respond to decreased sodium levels in the tubular fluid?

Afferent arteriole dilates to increase blood flow into the glomerulus

What is the primary role of specialized cells in the juxtaglomerular apparatus?

Regulating electrolyte balance

How does the afferent arteriole respond to increased sodium levels in the tubular fluid?

It constricts, reducing GFR

Which hormone is released by the adrenal glands in response to angiotensin II stimulation?

Aldosterone

During hormonal regulation involving the Renin-Angiotensin-Aldosterone System (RAAS), what is the effect of aldosterone?

Promotes sodium reabsorption

What triggers the release of Atrial Natriuretic Peptide (ANP) from cardiac atrial cells?

Increased blood volume and pressure

What is the role of Atrial Natriuretic Peptide (ANP) in the kidneys?

Inhibits sodium reabsorption

How does the kidneys help in regulating acid-base balance?

By secreting bicarbonate ions in the urine

Which statement accurately describes the function of the efferent arteriole?

Maintains blood flow out of the glomerulus

What is the primary effect of Angiotensin II on blood pressure?

Stimulates vasoconstriction

How does the juxtaglomerular apparatus respond to decreased sodium levels?

Dilates the afferent arteriole

What is the primary function of the efferent arteriole in the kidney nephron?

Regulating glomerular filtration rate (GFR)

How does tubuloglomerular feedback (TGF) regulate the glomerular filtration rate (GFR)?

By sensing changes in tubular fluid flow and composition

What is the purpose of autoregulation in the kidney's nephron?

To regulate renal blood flow based on blood pressure changes

How does the unique arrangement of arterioles contribute to the regulation of kidney function?

By maintaining glomerular filtration pressure and blood flow

Which arteriole brings blood into the glomerulus in the kidney?

Afferent arteriole

What is the relationship between renal blood supply and the glomerular filtration rate (GFR) in the kidney?

Optimal renal blood flow is crucial for stable GFR

How is glomerular filtration rate (GFR) regulated in the kidney nephron?

By adjusting factors like blood pressure and renal blood flow

What role do intrinsic properties of the afferent and efferent arterioles play in kidney function?

Maintaining glomerular filtration pressure

In the kidney, how do changes in glomerular filtration rate (GFR) indicate alterations in kidney function and overall health?

Changes in GFR reflect kidney function changes

Which mechanism ensures stable kidney function despite fluctuations in systemic blood pressure?

Renal autoregulation process

What plays a crucial role in maintaining glomerular filtration pressure and regulating blood flow within the nephron?

Efferent artery

Which mechanism helps ensure stable kidney function despite fluctuations in systemic blood pressure?

Autoregulation

What parameter is critical for assessing kidney function and is regulated by factors such as blood pressure and renal blood flow?

Glomerular Filtration Rate (GFR)

Which component of the nephron exerts intrinsic properties to regulate renal blood flow and Glomerular Filtration Rate (GFR)?

Afferent arteriole

How is the Glomerular Filtration Rate (GFR) maintained relatively constant despite changes in blood pressure?

By autoregulatory responses from arterioles

Which arteriole brings blood into the glomerulus and significantly influences the filtration process in the kidney nephron?

Afferent arteriole

In renal autoregulation, which structure primarily mediates the adjustment of its diameter to regulate blood flow and Glomerular Filtration Rate (GFR)?

Juxtaglomerular apparatus

What is the primary function of Atrial Natriuretic Peptide (ANP) in response to increased blood volume and pressure?

Inhibiting sodium and water excretion

How does the juxtaglomerular apparatus respond when sodium levels are decreased?

By dilating the afferent arteriole

Which hormone stimulates the vasoconstriction of arterioles to increase blood pressure?

Angiotensin II

How does Aldosterone contribute to water retention and increased blood volume?

By promoting sodium reabsorption

What is the impact of increased sodium levels in the tubular fluid on the afferent arteriole?

Constriction

How does Renin-Angiotensin-Aldosterone System (RAAS) react to low blood pressure?

Stimulates aldosterone release

What role does the Hormonal Regulation section play in modulating renal function and electrolyte balance?

Crucial role in modulating renal function

What is the primary function of the Renin-Angiotensin-Aldosterone System (RAAS) when stimulated by low sodium levels?

Initiates a cascade leading to increased sodium reabsorption

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