Anatomy of Skeletal and Smooth Muscles
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Anatomy of Skeletal and Smooth Muscles

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Questions and Answers

What is the primary difference in structure between skeletal muscle and smooth muscle?

  • Number of nuclei per cell
  • Type of protein filaments present
  • Presence or absence of striations (correct)
  • Shape of the muscle cells
  • What is the duration of the refractory period in skeletal muscle action potential?

  • ~250 ms
  • ~2 ms
  • ~5 ms (correct)
  • ~200-300 ms
  • What is the function of the sarcoplasmic reticulum in the skeletal muscle contraction cycle?

  • To release Ca2+ for muscle contraction (correct)
  • To release ATP for muscle contraction
  • To break down ATP and reduce muscle contraction
  • To sequester Ca2+ and prevent muscle contraction
  • What is the term for the amount of blood ejected by a ventricle per beat?

    <p>Stroke volume</p> Signup and view all the answers

    What is the correct sequence of events in the skeletal muscle contraction cycle?

    <p>Excitation, calcium release, cross-bridge formation, power stroke</p> Signup and view all the answers

    What is the term for the basic contractile unit of muscle fiber?

    <p>Sarcomere</p> Signup and view all the answers

    What is the duration of the action potential in cardiac muscle?

    <p>~200-300 ms</p> Signup and view all the answers

    What is the term for the wave of ventricular depolarization on an ECG?

    <p>QRS complex</p> Signup and view all the answers

    Study Notes

    Skeletal Muscle vs. Smooth Muscle Anatomy

    • Skeletal muscle: Multinucleated fibers, striated, and organized into sarcomeres and myofibrils, with components including epimysium, perimysium, endomysium, and fascicles
    • Smooth muscle: Single nucleus per cell, non-striated, with dense bodies instead of sarcomeres, and organized into sheets or bundles found in walls of hollow organs

    Action Potential in Cardiac vs. Skeletal Muscle

    • Skeletal muscle action potential: Short duration (~2 ms), short refractory period (~5 ms), and all-or-nothing propagation
    • Cardiac muscle action potential: Long duration (~200-300 ms), long refractory period (~250 ms), and graded propagation influenced by autonomic nervous system

    Skeletal Muscle Contraction Cycle

    • Excitation: Action potential arrives at neuromuscular junction
    • Calcium release: Sarcoplasmic reticulum releases Ca2+
    • Cross-bridge formation: Ca2+ binds to troponin, exposing binding sites on actin
    • Power stroke: Myosin heads pivot, pulling actin filaments
    • Detachment: ATP binds to myosin heads, causing them to release actin
    • Resetting: ATP is hydrolyzed, resetting myosin heads

    Sarcomere and Muscle Contraction/Relaxation

    • Sarcomere: Basic contractile unit of muscle fiber
    • Contraction: Actin and myosin filaments slide past each other, shortening the sarcomere
    • Relaxation: Calcium ions are pumped back into the sarcoplasmic reticulum, actin and myosin filaments return to resting position

    ECG and Cardiac Physiology

    • ECG: Electrocardiogram
    • P Wave: Atrial depolarization
    • QRS Complex: Ventricular depolarization
    • T Wave: Ventricular repolarization

    Cardiac Terms and Regulation

    • Stroke Volume (SV): Amount of blood ejected by a ventricle per beat, regulated by preload, contractility, and afterload
    • Cardiac Output (CO): Total volume of blood pumped by the ventricle per minute, calculated by CO = SV x Heart Rate (HR)
    • End-Diastolic Volume (EDV): Volume of blood in the ventricle at the end of diastole, affected by venous return and filling time
    • End-Systolic Volume (ESV): Volume of blood remaining in the ventricle after systole, affected by contractility and afterload
    • Preload: Degree of stretch of cardiac muscle fibers at the end of diastole, influenced by venous return

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    Description

    Compare and contrast the anatomy of skeletal and smooth muscles, including structure, organization, and components. Learn about the differences between these two types of muscles.

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