Skin Histology (MCQS)
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Questions and Answers

What is unique to each individual, even in identical twins?

  • Toe prints
  • Hand shape
  • Foot shape
  • Fingerprints (correct)
  • Which layer of the epidermis contains keratohyaline granules?

  • Stratum basale
  • Stratum corneum
  • Stratum lucidum
  • Stratum granulosum (correct)
  • What is the function of melanocytes in the skin?

  • To synthesize melanin (correct)
  • To regulate skin temperature
  • To protect the skin from UV radiation
  • To produce keratin
  • In which stage of melanosome development is melanin synthesis initiated?

    <p>Stage II</p> Signup and view all the answers

    What is the location of melanocytes in the skin?

    <p>Epidermis</p> Signup and view all the answers

    Which of the following is NOT a layer of the epidermis?

    <p>Stratum papillare</p> Signup and view all the answers

    What is the function of tyrosinase in melanin synthesis?

    <p>To catalyze melanin synthesis</p> Signup and view all the answers

    What is the size range of mature melanin granules?

    <p>0.5-1 μm</p> Signup and view all the answers

    What is the function of the Golgi apparatus in melanin synthesis?

    <p>To process and modify tyrosinase</p> Signup and view all the answers

    Which layer of the skin is composed of stratified squamous epithelial cells?

    <p>Epidermis</p> Signup and view all the answers

    Which type of cells play a crucial role in mediating immune response by binding, processing, and presenting antigens to T lymphocytes?

    <p>Langerhans cells</p> Signup and view all the answers

    What is the primary function of the dermal papillae in the skin?

    <p>To provide mechanical support to the skin</p> Signup and view all the answers

    What is the primary component of the skin's hypodermis?

    <p>Fatty tissue</p> Signup and view all the answers

    What is the term for the pattern of accumulation of fatty tissue in the skin?

    <p>Sex-dependent pattern</p> Signup and view all the answers

    What is the name of the layer of the hair root sheath that is composed of granular cells?

    <p>Huxley's layer</p> Signup and view all the answers

    What is the term for the phase of hair development characterized by active growth and mitotic activity?

    <p>Anagen</p> Signup and view all the answers

    What is the function of the sebaceous glands in the skin?

    <p>To produce sebum</p> Signup and view all the answers

    What is the term for the lines of tension in the skin formed by collagen and elastic fibers?

    <p>Langer's lines</p> Signup and view all the answers

    What is the term for the phase of hair development characterized by apoptosis and involution?

    <p>Catagen</p> Signup and view all the answers

    What is the name of the receptor responsible for detecting light touch and vibration in the skin?

    <p>Pacinian corpuscules</p> Signup and view all the answers

    What is the primary function of eccrine glands?

    <p>To produce true sweat</p> Signup and view all the answers

    What is the difference between apocrine and eccrine glands in terms of their ducts?

    <p>Apocrine glands have ducts that open into hair follicles, while eccrine glands have ducts that open into pores</p> Signup and view all the answers

    What is the characteristic of the telogen phase of the hair follicle?

    <p>A period of hair shedding</p> Signup and view all the answers

    What is the type of epithelium found in the stratatum germinativum?

    <p>Simple cuboidal epithelium</p> Signup and view all the answers

    What is the function of myoepithelial cells in the mammary gland?

    <p>To contract and expel milk</p> Signup and view all the answers

    What is the characteristic of the merocrine way of sweat gland secretion?

    <p>Both apocrine and eccrine glands release their products through merocrine secretion</p> Signup and view all the answers

    What is the difference between ceruminous glands and mammary glands?

    <p>Ceruminous glands secrete earwax, while mammary glands secrete milk</p> Signup and view all the answers

    What is the characteristic of the polygonal cells in the hair follicle?

    <p>They are polygonal in shape</p> Signup and view all the answers

    What is the difference between inactive and lactating mammary glands?

    <p>Inactive glands are smaller, while lactating glands are larger</p> Signup and view all the answers

    Study Notes

    Dermatoglyphics (Fingerprints)

    • Certain areas of the human skin show ridges and grooves, arranged in distinctive patterns, which are unique for each individual (even differing in identical twins)

    Skin Layers

    • The epidermis consists of:
      • Stratum corneum
      • Stratum lucidum
      • Stratum granulosum
      • Stratum spinosum
      • Stratum basale
    • The dermis consists of:
      • Papillary layer
      • Reticular layer

    Epidermal Cells

    • Produce keratin, the major structural protein of the epidermis
    • Melanocytes:
      • Derived from neural crest
      • Round cells with cytoplasmic (dendritic) projections scattered among the basal cells of the stratum basale
      • Synthesize tyrosinase in rough ER, processed through the Golgi apparatus, and accumulate in vesicles (stage I melanosomes)
      • Melanin synthesis begins in ovoid stage II melanosomes, and accumulates in stage III
      • Mature melanin granules (stage IV) have lost tyrosinase and other activities and have an internal matrix completely filled with melanin
    • Langerhans cells:
      • Bind, process, and present antigens to T lymphocytes, mediating immune response

    Skin Types

    • Thick skin (e.g. palms, soles)
    • Thin skin (e.g. limbs, torso)

    Dermal Papillae

    • Formed by collagen (type I) and elastic fibers regularly oriented, forming lines of tension in the skin (Langer's lines)

    Skin Receptors

    • Pacinian corpuscles
    • Meissner's corpuscles
    • Merkel cells
    • Ruffini's corpuscules

    Hypodermis

    • Also called "superficial fascia"
    • Fatty tissue which stores fat and anchors skin (areolar tissue and adipose cells)
    • Different patterns of accumulation (male/female)

    Hair

    • Pilosebaceous unit
    • Hair follicles and hairs
    • Phases of hair development:
      • Anagen (active phase)
      • Catagen (apoptosis-driven involution)
      • Telogen (resting phase)

    Sebaceous Glands

    • Associated with hair follicles
    • Produce sebum, an oily substance that lubricates hair and skin

    Sweat Glands

    • Types:
      • Eccrine (merocrine)
      • Apocrine
      • Modified apocrine (e.g. ceruminous, mammary)
    • Eccrine glands:
      • Most numerous
      • True sweat: 99% water, some salts, traces of waste
      • Open through pores
    • Apocrine glands:
      • Confined to axillary, anal, and genital areas
      • Ducts open into hair follicles
      • Organic molecules in it decompose with time, causing odor

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    Skin Lecture PDF

    Description

    This quiz covers the structure and composition of human skin, including the unique patterns of ridges and grooves, and the different layers of the skin.

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