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Questions and Answers
Which physiological change in old age can lead to constipation?
Which physiological change in old age can lead to constipation?
What is the main function of epithelial tissues?
What is the main function of epithelial tissues?
What is the role of a basement membrane in epithelial tissues?
What is the role of a basement membrane in epithelial tissues?
Which cellular feature allows epithelial cells to rapidly replace damaged cells?
Which cellular feature allows epithelial cells to rapidly replace damaged cells?
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What is the function of cilia in epithelial cells?
What is the function of cilia in epithelial cells?
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Why do epithelial tissues rely on a basement membrane?
Why do epithelial tissues rely on a basement membrane?
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How do microvilli contribute to the function of epithelial cells?
How do microvilli contribute to the function of epithelial cells?
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What is the main purpose of epithelial cells acting as a barrier?
What is the main purpose of epithelial cells acting as a barrier?
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What is the significance of epithelial tissue's interaction with internal and external environments?
What is the significance of epithelial tissue's interaction with internal and external environments?
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How do epithelial cells contribute to maintaining tissue integrity?
How do epithelial cells contribute to maintaining tissue integrity?
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Study Notes
Anatomical Directions
- Posterior (or dorsal) refers to the back or direction towards the back of the body
- Superior (or cranial) refers to a position above or higher than another part of the body
- Inferior (or caudal) refers to a position below or lower than another part of the body
- Lateral refers to the side or direction towards the side of the body
- Medial refers to the middle or direction towards the middle of the body
- Proximal refers to a position in a limb that is nearer to the point of attachment or the trunk of the body
- Distal refers to a position in a limb that is farther from the point of attachment or the trunk of the body
- Superficial refers to a position closer to the surface of the body
- Deep refers to a position farther from the surface of the body
Body Cavities
- Two major cavities: thoracic cavity and abdominal pelvic cavity
- Separated by the diaphragm
- Act to protect vital functions and allow organs to expand without disturbing other surrounding tissue
Cell Structure
- A cell can be divided into three main parts: plasma (cell) membrane, cytoplasm, and nucleus
- Organelles within the cytoplasm:
- Membranous organelles: covered with their own plasma membrane, isolating them from the cytosol
- Non-membranous organelles: no membrane, in direct contact with the cytosol
- Nucleus:
- Contains genetic material (DNA)
- Regulates cell activities
- Surrounded by a double membrane (nuclear envelope)
- Contains nucleolus, involved in ribosome synthesis
- Mitochondria:
- Powerhouse of the cell
- Site of cellular respiration
- Generates ATP (adenosine triphosphate) energy
- Has its own DNA (mitochondrial DNA)
- Endoplasmic Reticulum (ER):
- Rough ER: studded with ribosomes, involved in protein synthesis and processing
- Smooth ER: synthesizes lipids, detoxifies drugs and toxins
- Golgi Apparatus:
- Modifies, sorts, and packages proteins and lipids
- Forms vesicles for transport within the cell or secretion outside the cell
- Lysosomes:
- Contain digestive enzymes
- Break down cellular waste, foreign substances, and damaged organelles
- Recycling center of the cell
- Ribosomes:
- Site of protein synthesis
- Can be free in the cytoplasm or bound to the rough ER
Cell Specialization
- Cells vary greatly in size and shape, with around 200 different types in the human body
- Cell signaling and recognition:
- Integral proteins and carbohydrates on the cell surface are involved in cell signaling and recognition
- Receptor proteins bind to specific signaling molecules, triggering cellular responses
- Cell surface carbohydrates participate in cell recognition and immune responses
- Cellular transport:
- Integral proteins facilitate the transport of ions and molecules across the membrane
- Channel proteins form pores for passive transport, allowing ions to move down their concentration gradient
- Carrier proteins undergo conformational changes to transport specific molecules against their concentration gradient (active transport)
- Cell adhesion and support:
- Membrane proteins and carbohydrates mediate cell-cell adhesion and interactions with the extracellular matrix
- This adhesion is crucial for tissue formation, structural integrity, and stability of multicellular organisms
Membrane Transport
- Small, uncharged, lipid-soluble molecules can cross the lipid bilayer from ECF to ICF by simple diffusion
- Pinocytosis is a process where the cell sips up fluid and dissolved nutrients
- Phagocytosis is a process where the cell engulfs large particles or debris
- Tonicity:
- Isotonic solutions have the same solute concentration as inside the cell
- Hypertonic solutions have a higher concentration of solutes compared to inside the cell
- Hypotonic solutions have a lower concentration of solutes compared to inside the cell
Body Systems
- 11 body systems and their functions:
- Respiratory: breathing, lungs, trachea
- Cardiovascular/Circulatory: blood circulation, heart, arteries, veins, blood
- Digestive: processing food, mouth, pharynx, esophagus, stomach, intestines, accessory organs
- Endocrine: hormone production, glands throughout the body
- Urinary: waste elimination, kidneys, bladder
- Reproductive: reproduction, uterus, ovaries, fallopian tubes
- Nervous/Sensory: communication between and coordination of all body systems, nervous, brain, nerves, sensory
- Integumentary: protects against damage, skin, hair, nails
- Muscular/Skeletal: provides form, support, stability, and movement to the body, muscles, bones
- Hematopoietic/Lymphatic: blood production, maintenance of fluid balance, and defense against disease, bone marrow, spleen, tonsils, lymph fluid, nodes, ducts, vessels
Cell Communication
- Direct communication: juxtacrine (near) gap junction, contains two connexons per gap junction, allows cell-to-cell communication, direct small molecule, ions, glucose, very fast, gap junction in heart, brain, and smooth muscles
- Five main types of indirect cell-to-cell communication
Epithelial Tissue
- Cellularity and tissue organization:
- Epithelial tissues consist of closely packed cells with minimal extracellular matrix
- Form continuous sheets that cover body surfaces, line cavities and organs, and create glands
- High mitotic activity: epithelial cells have a high rate of mitosis, allowing for rapid replacement and repair of damaged cells
- Interaction with environments: epithelium interacts with both internal and external environments, acts as a barrier, protects underlying tissues from mechanical damage, pathogens, and dehydration, and facilitates the exchange of nutrients and wastes between body compartments
- Basement membrane: separates the epithelium from underlying connective tissue, facilitates the exchange of substances between epithelial cells and blood vessels
- Specializations: epithelial cells exhibit various specializations to perform specific functions effectively, examples include cilia, which move substances along the cell surface, and microvilli, which increase surface area for absorption or secretion
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Description
Test your knowledge of anatomical directional terms with this quiz. Identify the meanings of terms like posterior, superior, inferior, and lateral based on examples provided.