Podcast
Questions and Answers
Which part of the adrenal gland is of mesodermal origin?
Which part of the adrenal gland is of mesodermal origin?
Which hormones are produced by the adrenal cortex?
Which hormones are produced by the adrenal cortex?
Which part of the adrenal gland is of neural crest origin?
Which part of the adrenal gland is of neural crest origin?
Which hormones are produced by the adrenal medulla?
Which hormones are produced by the adrenal medulla?
Signup and view all the answers
Which of the following accurately describes the site of synthesis for cortisol?
Which of the following accurately describes the site of synthesis for cortisol?
Signup and view all the answers
What is the influence of stress on cortisol secretion?
What is the influence of stress on cortisol secretion?
Signup and view all the answers
How would you investigate a subject suspected of having Addison's disease?
How would you investigate a subject suspected of having Addison's disease?
Signup and view all the answers
What are some of the metabolic manifestations of Cushing's disease?
What are some of the metabolic manifestations of Cushing's disease?
Signup and view all the answers
Which of the following is a cause of hypercortisolism?
Which of the following is a cause of hypercortisolism?
Signup and view all the answers
Which of the following is a manifestation of primary Addison's disease?
Which of the following is a manifestation of primary Addison's disease?
Signup and view all the answers
What is the purpose of the Synacthen stimulation test?
What is the purpose of the Synacthen stimulation test?
Signup and view all the answers
What is the normal result of the Synacthen stimulation test?
What is the normal result of the Synacthen stimulation test?
Signup and view all the answers
Which of the following is a reference interval for salivary cortisol in adults in the afternoon?
Which of the following is a reference interval for salivary cortisol in adults in the afternoon?
Signup and view all the answers
What is the reference interval for salivary cortisol in neonatal babies in the morning?
What is the reference interval for salivary cortisol in neonatal babies in the morning?
Signup and view all the answers
Which of the following is a possible cause of Cushing's disease?
Which of the following is a possible cause of Cushing's disease?
Signup and view all the answers
What is the recommended storage temperature for saliva samples for cortisol measurement?
What is the recommended storage temperature for saliva samples for cortisol measurement?
Signup and view all the answers
Which of the following is true about the measurement of ACTH Circadian rhythm?
Which of the following is true about the measurement of ACTH Circadian rhythm?
Signup and view all the answers
What is the most common form of steroid hormone found in plasma?
What is the most common form of steroid hormone found in plasma?
Signup and view all the answers
How do unbound (free) steroid hormones enter cells?
How do unbound (free) steroid hormones enter cells?
Signup and view all the answers
What is the role of heat shock protein 90 (HSP 90) in the complex with unoccupied receptors?
What is the role of heat shock protein 90 (HSP 90) in the complex with unoccupied receptors?
Signup and view all the answers
Which of the following is a test used to determine the cause of hypercortisolism in Cushing's syndrome?
Which of the following is a test used to determine the cause of hypercortisolism in Cushing's syndrome?
Signup and view all the answers
What is the normal result for a low dose overnight dexamethasone suppression test?
What is the normal result for a low dose overnight dexamethasone suppression test?
Signup and view all the answers
Which of the following is NOT a manifestation of Cushing's syndrome?
Which of the following is NOT a manifestation of Cushing's syndrome?
Signup and view all the answers
What is the primary cause of hypercortisolism in Cushing's syndrome?
What is the primary cause of hypercortisolism in Cushing's syndrome?
Signup and view all the answers
Which process decreases the synthesis/release of hormones?
Which process decreases the synthesis/release of hormones?
Signup and view all the answers
Where does metabolism to water soluble forms of steroids mostly occur?
Where does metabolism to water soluble forms of steroids mostly occur?
Signup and view all the answers
What does the binding of the glucocorticoid receptor complex inhibit?
What does the binding of the glucocorticoid receptor complex inhibit?
Signup and view all the answers
What is the primary organ responsible for excreting water soluble forms of steroids?
What is the primary organ responsible for excreting water soluble forms of steroids?
Signup and view all the answers
What is the process that removes/inactivates hormones?
What is the process that removes/inactivates hormones?
Signup and view all the answers
What is the role of NFkB in gene transcription of the IL6 gene?
What is the role of NFkB in gene transcription of the IL6 gene?
Signup and view all the answers