Analgesics and Chemotherapy Pharmacology
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Questions and Answers

Which generation of cephalosporin has activity against methicillin-resistant staphylococci and broad gram-negative spectrum?

  • Fifth generation (correct)
  • Third generation
  • Second generation
  • Fourth generation

How is Ceftriaxone primarily excreted?

  • Through the liver
  • In the bile and feces (correct)
  • Through the skin
  • Through the kidneys

What is the common side effect of Ceftriaxone when administered with calcium?

  • Biliary sludge (correct)
  • Gut upset
  • Nephrotoxicity
  • Thrombophlebitis

What is the common allergy cross-reaction between cephalosporins and?

<p>Penicillins (D)</p> Signup and view all the answers

Which of the following cephalosporins may produce hypoprothrombinemia due to its anti-vitamin K effect?

<p>Cefamandole, cefoperazone, and cefotetan (B)</p> Signup and view all the answers

Which of the following is a characteristic of fourth-generation cephalosporins?

<p>Adequate levels in CSF (A)</p> Signup and view all the answers

What is the primary mechanism of excretion of cephalosporins?

<p>Tubular secretion and glomerular filtration (A)</p> Signup and view all the answers

What is the common side effect of cephalosporins when administered intramuscularly?

<p>Pain at the injection site (A)</p> Signup and view all the answers

Which of the following antibiotics is a monobactam?

<p>Aztreonam (A)</p> Signup and view all the answers

What is the characteristic of carbapenems?

<p>Broadest spectrum β-lactams (D)</p> Signup and view all the answers

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