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Analgesics and Chemotherapy Pharmacology
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Analgesics and Chemotherapy Pharmacology

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Questions and Answers

Which generation of cephalosporin has activity against methicillin-resistant staphylococci and broad gram-negative spectrum?

  • Fifth generation (correct)
  • Third generation
  • Second generation
  • Fourth generation

    • How is Ceftriaxone primarily excreted?

  • Through the liver
  • In the bile and feces (correct)
  • Through the skin
  • Through the kidneys

    • What is the common side effect of Ceftriaxone when administered with calcium?

  • Biliary sludge (correct)
  • Gut upset
  • Nephrotoxicity
  • Thrombophlebitis

    • What is the common allergy cross-reaction between cephalosporins and?

    <p>Penicillins</p> Signup and view all the answers

    Which of the following cephalosporins may produce hypoprothrombinemia due to its anti-vitamin K effect?

    <p>Cefamandole, cefoperazone, and cefotetan</p> Signup and view all the answers

    Which of the following is a characteristic of fourth-generation cephalosporins?

    <p>Adequate levels in CSF</p> Signup and view all the answers

    What is the primary mechanism of excretion of cephalosporins?

    <p>Tubular secretion and glomerular filtration</p> Signup and view all the answers

    What is the common side effect of cephalosporins when administered intramuscularly?

    <p>Pain at the injection site</p> Signup and view all the answers

    Which of the following antibiotics is a monobactam?

    <p>Aztreonam</p> Signup and view all the answers

    What is the characteristic of carbapenems?

    <p>Broadest spectrum β-lactams</p> Signup and view all the answers

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