Podcast
Questions and Answers
Which enzyme is bypassed in the liver due to the manner in which fructose is processed?
Which enzyme is bypassed in the liver due to the manner in which fructose is processed?
- Phosphofructokinase (correct)
- Hexokinase
- Pyruvate kinase
- Lactase
What does glycolysis primarily provide in muscle?
What does glycolysis primarily provide in muscle?
- Regulation of fatty acid synthesis
- Breakdown of amino acids
- Energy for muscle contraction (correct)
- Building blocks for biosynthetic processes
What determines the control of glycolysis in muscle?
What determines the control of glycolysis in muscle?
- Energy state of the cell (ATP:AMP ratio) (correct)
- Presence of lactate
- Amount of galactose metabolism
- Ratio of fructose to glucose
Which tissue has several fundamental differences in the regulation of glycolysis compared to muscle?
Which tissue has several fundamental differences in the regulation of glycolysis compared to muscle?
What is the role of fructose-1,6-bisP in glycolysis?
What is the role of fructose-1,6-bisP in glycolysis?
Why does pyruvate kinase activity increase when there is a rise in fructose-1,6-bisP?
Why does pyruvate kinase activity increase when there is a rise in fructose-1,6-bisP?
Which tissue primarily obtains its energy needs from the breakdown of fatty acids?
Which tissue primarily obtains its energy needs from the breakdown of fatty acids?
What is one major function of the liver related to glucose?
What is one major function of the liver related to glucose?
How does the liver use glucose for biosynthesis?
How does the liver use glucose for biosynthesis?
Which enzyme is described as the most important control point in mammalian glycolysis?
Which enzyme is described as the most important control point in mammalian glycolysis?
What effect does ATP have on the catalytic activity of phosphofructokinase?
What effect does ATP have on the catalytic activity of phosphofructokinase?
Why is hexokinase not considered the control point in the glycolysis pathway?
Why is hexokinase not considered the control point in the glycolysis pathway?
Which molecule competes with ATP for binding to the same site on phosphofructokinase?
Which molecule competes with ATP for binding to the same site on phosphofructokinase?
Why is pyruvate kinase allosterically activated by fructose-1,6-bisP?
Why is pyruvate kinase allosterically activated by fructose-1,6-bisP?
What is the major point of regulation in Liver Phosphofructokinase (PFK)?
What is the major point of regulation in Liver Phosphofructokinase (PFK)?
Why do ATP and pH play less of a role in regulating PFK in the liver compared to muscle?
Why do ATP and pH play less of a role in regulating PFK in the liver compared to muscle?
What is the unique response of liver glycolysis to high blood sugar levels?
What is the unique response of liver glycolysis to high blood sugar levels?
What is the role of fructose-6-P in liver glycolysis?
What is the role of fructose-6-P in liver glycolysis?
How does citrate affect glycolysis regulation in the liver?
How does citrate affect glycolysis regulation in the liver?
Which molecule is the main regulatory point of glycolysis?
Which molecule is the main regulatory point of glycolysis?
What pH level, reached during extreme exercise, inhibits phosphofructokinase?
What pH level, reached during extreme exercise, inhibits phosphofructokinase?
Which compound serves as the entry point into the citric acid cycle and the electron transport chain?
Which compound serves as the entry point into the citric acid cycle and the electron transport chain?
Which sugar is commonly found in sucrose and corn syrup?
Which sugar is commonly found in sucrose and corn syrup?
How is NAD+ regenerated in the pyruvate to acetyl CoA conversion?
How is NAD+ regenerated in the pyruvate to acetyl CoA conversion?
What is the main reason why the pathway from glucose to pyruvate is referred to as anaerobic glycolysis?
What is the main reason why the pathway from glucose to pyruvate is referred to as anaerobic glycolysis?
What problem would arise in the cell if the conversion of glucose to pyruvate stopped and did not proceed further?
What problem would arise in the cell if the conversion of glucose to pyruvate stopped and did not proceed further?
Which molecule is consumed in the reaction catalyzed by glyceraldehyde-3-P dehydrogenase in glycolysis?
Which molecule is consumed in the reaction catalyzed by glyceraldehyde-3-P dehydrogenase in glycolysis?
What is a possible fate of pyruvate when oxygen is not available?
What is a possible fate of pyruvate when oxygen is not available?
In what way does the conversion of pyruvate to ethanol contribute to metabolic regulation?
In what way does the conversion of pyruvate to ethanol contribute to metabolic regulation?
Why is glycolysis usually studied first among many metabolic pathways?
Why is glycolysis usually studied first among many metabolic pathways?
Where does glycolysis take place in eukaryotic cells?
Where does glycolysis take place in eukaryotic cells?
What are the end products of glycolysis?
What are the end products of glycolysis?
Which function does glycolysis NOT serve?
Which function does glycolysis NOT serve?
What is the main reason for starting the study of metabolism with glycolysis?
What is the main reason for starting the study of metabolism with glycolysis?
Which cellular compartment houses the enzymes responsible for glycolysis?
Which cellular compartment houses the enzymes responsible for glycolysis?
If fructose bypasses an enzyme in the liver, which enzyme is bypassed?
If fructose bypasses an enzyme in the liver, which enzyme is bypassed?
Which of the following is NOT a function of glycolysis intermediates?
Which of the following is NOT a function of glycolysis intermediates?
What happens when glucose is transported into a eukaryotic cell with respect to glycolysis?
What happens when glucose is transported into a eukaryotic cell with respect to glycolysis?
What makes glycolysis an essential pathway in glucose metabolism?
What makes glycolysis an essential pathway in glucose metabolism?
