Podcast
Questions and Answers
Which enzyme is bypassed in the liver due to the manner in which fructose is processed?
Which enzyme is bypassed in the liver due to the manner in which fructose is processed?
What does glycolysis primarily provide in muscle?
What does glycolysis primarily provide in muscle?
What determines the control of glycolysis in muscle?
What determines the control of glycolysis in muscle?
Which tissue has several fundamental differences in the regulation of glycolysis compared to muscle?
Which tissue has several fundamental differences in the regulation of glycolysis compared to muscle?
Signup and view all the answers
What is the role of fructose-1,6-bisP in glycolysis?
What is the role of fructose-1,6-bisP in glycolysis?
Signup and view all the answers
Why does pyruvate kinase activity increase when there is a rise in fructose-1,6-bisP?
Why does pyruvate kinase activity increase when there is a rise in fructose-1,6-bisP?
Signup and view all the answers
Which tissue primarily obtains its energy needs from the breakdown of fatty acids?
Which tissue primarily obtains its energy needs from the breakdown of fatty acids?
Signup and view all the answers
What is one major function of the liver related to glucose?
What is one major function of the liver related to glucose?
Signup and view all the answers
How does the liver use glucose for biosynthesis?
How does the liver use glucose for biosynthesis?
Signup and view all the answers
Which enzyme is described as the most important control point in mammalian glycolysis?
Which enzyme is described as the most important control point in mammalian glycolysis?
Signup and view all the answers
What effect does ATP have on the catalytic activity of phosphofructokinase?
What effect does ATP have on the catalytic activity of phosphofructokinase?
Signup and view all the answers
Why is hexokinase not considered the control point in the glycolysis pathway?
Why is hexokinase not considered the control point in the glycolysis pathway?
Signup and view all the answers
Which molecule competes with ATP for binding to the same site on phosphofructokinase?
Which molecule competes with ATP for binding to the same site on phosphofructokinase?
Signup and view all the answers
Why is pyruvate kinase allosterically activated by fructose-1,6-bisP?
Why is pyruvate kinase allosterically activated by fructose-1,6-bisP?
Signup and view all the answers
What is the major point of regulation in Liver Phosphofructokinase (PFK)?
What is the major point of regulation in Liver Phosphofructokinase (PFK)?
Signup and view all the answers
Why do ATP and pH play less of a role in regulating PFK in the liver compared to muscle?
Why do ATP and pH play less of a role in regulating PFK in the liver compared to muscle?
Signup and view all the answers
What is the unique response of liver glycolysis to high blood sugar levels?
What is the unique response of liver glycolysis to high blood sugar levels?
Signup and view all the answers
What is the role of fructose-6-P in liver glycolysis?
What is the role of fructose-6-P in liver glycolysis?
Signup and view all the answers
How does citrate affect glycolysis regulation in the liver?
How does citrate affect glycolysis regulation in the liver?
Signup and view all the answers
Which molecule is the main regulatory point of glycolysis?
Which molecule is the main regulatory point of glycolysis?
Signup and view all the answers
What pH level, reached during extreme exercise, inhibits phosphofructokinase?
What pH level, reached during extreme exercise, inhibits phosphofructokinase?
Signup and view all the answers
Which compound serves as the entry point into the citric acid cycle and the electron transport chain?
Which compound serves as the entry point into the citric acid cycle and the electron transport chain?
Signup and view all the answers
Which sugar is commonly found in sucrose and corn syrup?
Which sugar is commonly found in sucrose and corn syrup?
Signup and view all the answers
How is NAD+ regenerated in the pyruvate to acetyl CoA conversion?
How is NAD+ regenerated in the pyruvate to acetyl CoA conversion?
Signup and view all the answers
What is the main reason why the pathway from glucose to pyruvate is referred to as anaerobic glycolysis?
What is the main reason why the pathway from glucose to pyruvate is referred to as anaerobic glycolysis?
Signup and view all the answers
What problem would arise in the cell if the conversion of glucose to pyruvate stopped and did not proceed further?
What problem would arise in the cell if the conversion of glucose to pyruvate stopped and did not proceed further?
Signup and view all the answers
Which molecule is consumed in the reaction catalyzed by glyceraldehyde-3-P dehydrogenase in glycolysis?
Which molecule is consumed in the reaction catalyzed by glyceraldehyde-3-P dehydrogenase in glycolysis?
Signup and view all the answers
What is a possible fate of pyruvate when oxygen is not available?
What is a possible fate of pyruvate when oxygen is not available?
Signup and view all the answers
In what way does the conversion of pyruvate to ethanol contribute to metabolic regulation?
In what way does the conversion of pyruvate to ethanol contribute to metabolic regulation?
Signup and view all the answers
Why is glycolysis usually studied first among many metabolic pathways?
Why is glycolysis usually studied first among many metabolic pathways?
Signup and view all the answers
Where does glycolysis take place in eukaryotic cells?
Where does glycolysis take place in eukaryotic cells?
Signup and view all the answers
What are the end products of glycolysis?
What are the end products of glycolysis?
Signup and view all the answers
Which function does glycolysis NOT serve?
Which function does glycolysis NOT serve?
Signup and view all the answers
What is the main reason for starting the study of metabolism with glycolysis?
What is the main reason for starting the study of metabolism with glycolysis?
Signup and view all the answers
Which cellular compartment houses the enzymes responsible for glycolysis?
Which cellular compartment houses the enzymes responsible for glycolysis?
Signup and view all the answers
If fructose bypasses an enzyme in the liver, which enzyme is bypassed?
If fructose bypasses an enzyme in the liver, which enzyme is bypassed?
Signup and view all the answers
Which of the following is NOT a function of glycolysis intermediates?
Which of the following is NOT a function of glycolysis intermediates?
Signup and view all the answers
What happens when glucose is transported into a eukaryotic cell with respect to glycolysis?
What happens when glucose is transported into a eukaryotic cell with respect to glycolysis?
Signup and view all the answers
What makes glycolysis an essential pathway in glucose metabolism?
What makes glycolysis an essential pathway in glucose metabolism?
Signup and view all the answers
