Amyopathic Dermatomyositis Classification

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Questions and Answers

What is the focus of the study mentioned in the text?

  • Distinctive cutaneous and systemic features associated with antitranscriptional intermediary factor-1gamma antibodies
  • Drug-induced dermatomyositis after zoledronic acid
  • Associations of tumor necrosis factor alpha and HLA polymorphisms (correct)
  • Review of drug-induced dermatomyositis

Which publication discusses drug-induced dermatomyositis after zoledronic acid?

  • Australas J Dermatol 2012;53:e73–5 (correct)
  • Rheumatology (Oxford) 2009;48:607–12
  • J Cutan Pathol 2008;35:74–81
  • JAMA Dermatol 2015;151:195–9

Who authored the review of drug-induced dermatomyositis discussed in the text?

  • Werth VP, Callen JP, Ang G, Sullivan KE (correct)
  • Gunawardena H, Betteridge ZE, McHugh NJ
  • Tong PL, Yu LL, Chan JJ
  • Sheik Ali S, Goddard AL, Luke JJ

What is the clinical significance of antinuclear antibodies?

<p>Their pathogenic significance in disease expression (C)</p> Signup and view all the answers

What percentage of dermatomyositis patients have clinically amyopathic disease?

<p>20% (A)</p> Signup and view all the answers

According to the revised classification proposed by Sontheimer, is muscle involvement still required for a definitive diagnosis of amyopathic forms of dermatomyositis?

<p>No, it is no longer required (C)</p> Signup and view all the answers

In adults, how does dermatomyositis affect women compared to men?

<p>Affects women twice as much as men (A)</p> Signup and view all the answers

How can adult-onset and juvenile-onset amyopathic DM and hypomyopathic DM be further subcategorized as?

<p>&quot;Provisional&quot; and &quot;confirmed&quot; (C)</p> Signup and view all the answers

What is the recommended pre-treatment warning for this medication?

<p>To test for allergic reactions (B)</p> Signup and view all the answers

Which treatment approach is commonly used for cutaneous dermatomyositis that is refractory to antimalarials?

<p>Mycophenolate mofetil followed by IVIg (C)</p> Signup and view all the answers

Which therapy is NOT mentioned as a potential treatment for calcinosis cutis?

<p>Infliximab (B)</p> Signup and view all the answers

How does early and aggressive therapy of juvenile dermatomyositis affect the risk of calcinosis cutis?

<p>It reduces the risk of calcinosis cutis (D)</p> Signup and view all the answers

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