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Questions and Answers
What is the therapeutic class of Aminocaproic acid (Amicar)?
What is the therapeutic class of Aminocaproic acid (Amicar)?
Clot stabilizer
What is the pharmacological class of Aminocaproic acid (Amicar)?
What is the pharmacological class of Aminocaproic acid (Amicar)?
Hemostatic/antifibrinolytic
What is the mechanism of action of Aminocaproic acid (Amicar)?
What is the mechanism of action of Aminocaproic acid (Amicar)?
Drug inactivates plasminogen, precursor of enzyme plasmin that digests the fibrin clot
What are the main uses of Aminocaproic acid (Amicar)?
What are the main uses of Aminocaproic acid (Amicar)?
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What are the adverse effects of Aminocaproic acid (Amicar)?
What are the adverse effects of Aminocaproic acid (Amicar)?
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What are the contraindications for using Aminocaproic acid (Amicar)?
What are the contraindications for using Aminocaproic acid (Amicar)?
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What are the drug interactions associated with Aminocaproic acid (Amicar)?
What are the drug interactions associated with Aminocaproic acid (Amicar)?
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What are the administration alerts for Aminocaproic acid (Amicar)?
What are the administration alerts for Aminocaproic acid (Amicar)?
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Study Notes
Aminocaproic Acid Overview
- Aminocaproic acid is classified as a clot stabilizer within the therapeutic class.
- It falls under the pharmacological class of hemostatic and antifibrinolytic agents.
Mechanism of Action
- Functions by inactivating plasminogen, which is the precursor to plasmin, an enzyme that digests fibrin clots.
Clinical Uses
- Effective in treating excessive bleeding caused by premature clot dissolution.
- Administered intravenously during acute hemorrhages, achieving effects within 1-2 hours.
- Available in tablet form, widely used post-surgery to reduce bleeding.
- May be given to Hemophilia A patients following dental procedures.
- Recommended therapeutic serum level is between 100-400 mcg/mL.
Adverse Effects
- Caution advised for patients with a history of thromboembolic disease.
- Rapid intravenous administration can lead to hypotension or bradycardia.
- Overall side effects tend to be mild.
Contraindications
- Not suitable for patients with disseminated intravascular clotting or chronic kidney disease.
Drug Interactions
- Use with estrogens or oral contraceptives can result in hypercoagulation.
- May cause elevated serum potassium levels in lab tests.
Administration Alerts
- Monitoring for hypotension and bradycardia is critical during IV administration.
- Frequent vital signs assessment is necessary, along with cardiac monitoring to detect any dysrhythmias.
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Description
Test your knowledge of Aminocaproic acid (Amicar) with these flashcards. Learn about its therapeutic and pharmacological classes, mechanism of action, and common uses in treating excessive bleeding. This quiz is perfect for students in pharmacology or related fields.
