Amino Acids
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Questions and Answers

Which of the following statements about amino acids is true?

  • Amino acids have only acidic properties
  • Amino acids have only basic properties
  • Amino acids are linear homopolymers of a-amino acids
  • Amino acids have diverse physical and chemical properties (correct)
  • What is the common structural feature of most a-amino acids?

  • The a-carbon has two substituents and is linear
  • The a-carbon has four substituents and is tetrahedral (correct)
  • The a-carbon has five substituents and is trigonal bipyramidal
  • The a-carbon has three substituents and is planar
  • Which of the following is NOT a common feature of all amino acids (except proline)?

  • A fourth substituent (R), unique
  • A basic amino group
  • An a-hydrogen connected to the a-carbon (correct)
  • An acidic carboxyl group
  • What is the relationship between L/D and the configuration of amino acids?

    <p>L/D represent the relative configuration of amino acids to L- and D-glyceraldehyde</p> Signup and view all the answers

    What is the average molecular weight of an amino acid residue?

    <p>About 110</p> Signup and view all the answers

    Which of the following is true about peptides and proteins?

    <p>Peptides are kinetically stable.</p> Signup and view all the answers

    What is the typical duration a peptide bond would last in an aqueous environment in the absence of a catalyst?

    <p>More than 1,000 years</p> Signup and view all the answers

    Which of the following contributes to the isoelectric point (pI) of a peptide or protein?

    <p>Both the terminal amino and carboxyl groups</p> Signup and view all the answers

    Which of the following is an example of a conjugated protein?

    <p>Hemoglobin</p> Signup and view all the answers

    What is commonly used for preparative separation of proteins?

    <p>Chromatography</p> Signup and view all the answers

    Which of the following statements is true about amino acids with uncharged side chains?

    <p>They can act as buffers in solution.</p> Signup and view all the answers

    Which of the following is true about the ionization of amino acids?

    <p>At neutral pH, the amino group is protonated and the carboxyl group is deprotonated.</p> Signup and view all the answers

    Which of the following is true about the isoelectric point (pI) of amino acids?

    <p>It is the pH at which amino acids carry a net charge of zero.</p> Signup and view all the answers

    Which of the following is true about ionizable side chains in amino acids?

    <p>They can show up in titration curves.</p> Signup and view all the answers

    What is the general calculation for determining the pI (isoelectric point) when the side chain of an amino acid is ionizable?

    <p>Identify the species that carries a net zero charge and take the average of its pKa values.</p> Signup and view all the answers

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