Questions and Answers
Which neurotransmitter's example is NOT correctly matched with its type?
Which of the following features is NOT typically associated with Parkinson's disease?
What is the primary focus of the final exam in terms of syllabus content?
Which of the following is a type of question included in the final exam format?
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How many marks is the Mix and Match question worth in the final exam format?
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Which feature of neuroplasticity is acknowledged in the learning objectives?
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What is the primary role of neurotransmitters in the body?
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What can result from imbalances in neurotransmitter levels?
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How do neurotransmitters influence psychological functions?
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What body functions are controlled by neurotransmitters?
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Where are neurotransmitters primarily produced in a neuron?
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What is a consequence of excessively high levels of neurotransmitters?
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In which of the following ways do neurotransmitters impact sensory perception?
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What aspect of neurotransmitters relates to sleep and healing?
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What condition is associated with an excess of serotonin?
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Which neurotransmitter's dysfunction is primarily linked to Parkinsonism?
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What effect do selective serotonin reuptake inhibitors (SSRIs) have on neurotransmitter activity?
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What might result from inflammation and damage of the synaptic cleft?
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Which medication type is used to improve memory and cognitive function in Alzheimer’s by blocking an enzyme?
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What is a potential outcome of too quick reabsorption of neurotransmitters?
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Which condition is linked with high levels of acetylcholine?
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How do medications that block the release of a neurotransmitter affect neurochemistry?
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Which type of genetic mutation specifically involves CAG repeat expansions?
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What primarily characterizes epigenetic changes in gene activity?
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What is the primary cause of most prion diseases?
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Which syndrome is specifically linked to mutations in the MECP2 gene?
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Familial Creutzfeldt-Jakob disease is an example of what type of disease?
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Which of the following is NOT a primary genetic cause of neurological disorders?
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What type of mutation is primarily associated with Huntington's disease?
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Which genetic factor is prominently associated with Alzheimer's disease?
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What are copy number variations (CNVs) associated with?
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Which neurological disorder is linked to mitochondrial DNA mutations?
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What causes repeat expansion disorders in neurological conditions?
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Which disorder arises from multiple gene (polygenic) involvement?
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How do environmental factors relate to polygenic neurological disorders?
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Which condition is NOT typically caused by copy number variations (CNVs)?
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Study Notes
Final Exam Overview
- Final exam contributes to 30% of the overall grade, assessing knowledge from syllabus topics covered post-midterm.
- Exam question types include True or False, Multiple Choice, Matching, and Short Answer.
Exam Question Types
- True or False: Simple statements requiring a true/false response.
- Multiple Choice: Questions offering four answer options, seeking identification of the correct one.
- Matching: Participants must relate different categories like neurotransmitter types to given examples.
- Short Answer: Typically asks for specific information, including features of neurological conditions.
Neurotransmitters
- Chemical messengers enabling communication between neurons and target tissues during synaptic transmission.
- Critical for managing various body functions, including automatic responses (breathing, heart rate) and psychological processes (mood regulation, learning).
- Imbalances in neurotransmitter levels can lead to health issues and are targeted by various medications.
Functions Controlled by Neurotransmitters
- Regulate heartbeat, blood pressure, muscle movements, memory, learning, and emotions.
- Influence sleep, healing processes, stress responses, hormone regulation, and digestion.
Neurotransmission Mechanism
- Involves neuron structures: cell body produces neurotransmitters; axon transmits signals.
- Conditions affecting neurotransmitter balance include production deficits, receptor defects, rapid reabsorption, and enzyme interference.
Diseases Associated with Neurotransmitters
- Disorders linked to high levels: Epilepsy, Alzheimer’s disease, Autism, Schizophrenia.
- Disorders linked to low levels: Parkinson's disease.
Effects of Medications on Neurotransmitters
- Some drugs inhibit enzymes that break down neurotransmitters, enhancing their effectiveness (e.g., Donepezil for Alzheimer’s).
- Selective Serotonin Reuptake Inhibitors (SSRIs) block serotonin reuptake, aiding in treating depression and anxiety.
- Some medications prevent neurotransmitter release, impacting conditions like Huntington's disease.
Genetic Causes of Neurological Disorders
- Polygenic Disorders: Result from mutations in multiple genes combined with environmental influences, e.g., Alzheimer’s and the APOE ε4 allele.
- Copy Number Variations (CNVs): Abnormal DNA copy numbers linked to epilepsy and autism.
- Mitochondrial DNA Mutations: Affect energy production in neurons, linked to disorders like Leber’s optic neuropathy.
- Repeat Expansion Disorders: Caused by abnormal DNA sequence repetitions leading to disorders like Huntington's and Fragile X syndrome.
- Epigenetic Changes: Alter gene activity without DNA sequence changes, associated with conditions like Rett syndrome.
- Prion Diseases: Result from misfolded proteins; examples include familial Creutzfeldt-Jakob disease.
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Description
This quiz focuses on the concepts and issues related to Alzheimer's Disease, specifically covering material after the midterm exam. It includes various question formats, such as True/False and multiple-choice, designed to test your knowledge and understanding of the syllabus content.
