Podcast
Questions and Answers
Which of the following factors is related to drug absorption?
Which of the following factors is related to drug absorption?
- Greater absorption for highly ionized drugs
- Greater absorption for lipid soluble drugs (correct)
- Greater absorption for water soluble drugs
- Greater absorption for large molecular size
What is the effect of molecular size on drug absorption?
What is the effect of molecular size on drug absorption?
- No effect of molecular size on absorption
- Decreased absorption for molecular size > 1000
- High absorption for molecular size > 1000
- Low absorption for molecular size > 1000 (correct)
How does particle size affect drug absorption?
How does particle size affect drug absorption?
- Absorption decreases for small particle size
- Absorption increases for large particle size
- No effect of particle size on absorption
- Absorption increases for small particle size (correct)
What is the effect of ionization on drug absorption?
What is the effect of ionization on drug absorption?
Which type of drugs have low absorption due to molecular size?
Which type of drugs have low absorption due to molecular size?
Which type of drugs have greater absorption due to lipid solubility?
Which type of drugs have greater absorption due to lipid solubility?
Which factor affects drug absorption in the body the most?
Which factor affects drug absorption in the body the most?
Which type of drugs have high distribution in the body?
Which type of drugs have high distribution in the body?
Which factor affects drug metabolism clearance the most?
Which factor affects drug metabolism clearance the most?
Which type of drugs have low clearance in the body?
Which type of drugs have low clearance in the body?
What factor affects drug excretion clearance the most?
What factor affects drug excretion clearance the most?
Which type of drugs have high clearance in the body?
Which type of drugs have high clearance in the body?
Which factor affects drug distribution in the body the most?
Which factor affects drug distribution in the body the most?
Which of the following is a factor that can lead to variable bioavailability in neonates and pediatric patients?
Which of the following is a factor that can lead to variable bioavailability in neonates and pediatric patients?
What is one of the differences in distribution between neonates and adults?
What is one of the differences in distribution between neonates and adults?
Which of the following is a factor that can contribute to reduced bioavailability in geriatric patients?
Which of the following is a factor that can contribute to reduced bioavailability in geriatric patients?
What is one of the changes in metabolism commonly seen in geriatric patients?
What is one of the changes in metabolism commonly seen in geriatric patients?
Which of the following is a consideration when dosing for patients with chronic cardiovascular disease?
Which of the following is a consideration when dosing for patients with chronic cardiovascular disease?
What is one of the main issues for intravenous anaesthetics in patients with respiratory disease?
What is one of the main issues for intravenous anaesthetics in patients with respiratory disease?
What is one of the changes in liver disease that can affect drug metabolism?
What is one of the changes in liver disease that can affect drug metabolism?
Which type of drugs may require therapeutic monitoring in patients with chronic respiratory disease?
Which type of drugs may require therapeutic monitoring in patients with chronic respiratory disease?
What does the therapeutic index of a drug measure?
What does the therapeutic index of a drug measure?
Which drugs have a high therapeutic index?
Which drugs have a high therapeutic index?
Which drugs have a low therapeutic index?
Which drugs have a low therapeutic index?
What is the purpose of therapeutic monitoring?
What is the purpose of therapeutic monitoring?
When is the best time to sample for therapeutic effect monitoring?
When is the best time to sample for therapeutic effect monitoring?
What should be ensured when investigating potential toxicity?
What should be ensured when investigating potential toxicity?
Which patients may require therapeutic monitoring for drugs with altered pharmacokinetics?
Which patients may require therapeutic monitoring for drugs with altered pharmacokinetics?
What is the ideal characteristic of a drug's therapeutic index?
What is the ideal characteristic of a drug's therapeutic index?
Which of the following factors affects drug absorption the most?
Which of the following factors affects drug absorption the most?
Which type of drugs are more likely to have low absorption due to molecular size?
Which type of drugs are more likely to have low absorption due to molecular size?
What is the effect of particle size on drug absorption?
What is the effect of particle size on drug absorption?
Which of the following is true about the effect of ionization on drug absorption?
Which of the following is true about the effect of ionization on drug absorption?
Which factor affects drug absorption the most?
Which factor affects drug absorption the most?
Which type of drugs are difficult to cross membranes due to ionization?
Which type of drugs are difficult to cross membranes due to ionization?
What is the effect of molecular size on drug absorption?
What is the effect of molecular size on drug absorption?
Which factor affects drug absorption the most?
Which factor affects drug absorption the most?
Which factor affects drug distribution in the body the most?
Which factor affects drug distribution in the body the most?
Which factor affects drug metabolism clearance the most?
Which factor affects drug metabolism clearance the most?
Which factor affects drug excretion clearance the most?
Which factor affects drug excretion clearance the most?
Which type of drugs have high drug distribution in the body?
Which type of drugs have high drug distribution in the body?
Which type of drugs have low drug distribution in the body?
Which type of drugs have low drug distribution in the body?
Which factor affects drug plasma protein binding the most?
Which factor affects drug plasma protein binding the most?
Which of the following factors can lead to a variable bioavailability of drugs in neonates and pediatric patients?
Which of the following factors can lead to a variable bioavailability of drugs in neonates and pediatric patients?
Which of the following is a characteristic of drug metabolism in neonates and foals?
Which of the following is a characteristic of drug metabolism in neonates and foals?
Which of the following is a consideration when dosing for geriatric patients?
Which of the following is a consideration when dosing for geriatric patients?
Which of the following is a characteristic of drug absorption in geriatric patients?
Which of the following is a characteristic of drug absorption in geriatric patients?
Which of the following is a characteristic of drug distribution in neonates?
Which of the following is a characteristic of drug distribution in neonates?
Which of the following is a consideration when dosing for patients with chronic cardiovascular disease?
Which of the following is a consideration when dosing for patients with chronic cardiovascular disease?
Which of the following is a characteristic of drug excretion in patients with renal disease?
Which of the following is a characteristic of drug excretion in patients with renal disease?
Which of the following is NOT a reason for measuring plasma concentration of drugs in special situations?
Which of the following is NOT a reason for measuring plasma concentration of drugs in special situations?
What does the therapeutic window represent on the graph?
What does the therapeutic window represent on the graph?
Which of the following drugs is likely to have a high therapeutic index?
Which of the following drugs is likely to have a high therapeutic index?
Which of the following drugs is likely to have a low therapeutic index?
Which of the following drugs is likely to have a low therapeutic index?
When is the best time to sample for therapeutic effect monitoring?
When is the best time to sample for therapeutic effect monitoring?
Which of the following is NOT a reason for therapeutic monitoring of pharmacokinetics?
Which of the following is NOT a reason for therapeutic monitoring of pharmacokinetics?
What is the purpose of sampling peak concentrations during therapeutic monitoring?
What is the purpose of sampling peak concentrations during therapeutic monitoring?
What is the purpose of sampling trough concentrations during therapeutic monitoring?
What is the purpose of sampling trough concentrations during therapeutic monitoring?
Which of the following drugs may require therapeutic monitoring in patients with chronic respiratory disease?
Which of the following drugs may require therapeutic monitoring in patients with chronic respiratory disease?
