Questions and Answers
What is the classification of Alprostadil?
What are the therapeutic uses of Alprostadil?
What is the mechanism of action (MOA) of Alprostadil?
Relaxes smooth muscle of the ductus arteriosus for PDA and helps with penile erection.
What are some adverse effects of Alprostadil?
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What nursing considerations are important when administering Alprostadil?
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Alprostadil has serious interactions with alcohol.
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Study Notes
Alprostadil Overview
- Alprostadil is classified as a prostaglandin 1 and is used primarily as an erectile dysfunction agent.
- It has therapeutic applications for congenital heart defects and erectile dysfunction.
Mechanism of Action (MOA)
- Relaxes smooth muscle of the ductus arteriosus for patent ductus arteriosus (PDA) management.
- Regulates blood flow to facilitate the opening and closing of heart chambers.
- Acts as a validator of cavernosal arteries, promoting penile erection and allowing for intercourse.
Adverse Effects
- Potential side effects include hypertension or hypotension, headaches (HA), dizziness, cough, bleeding, penile pain, edema, and hematoma especially with injection.
Nursing Considerations
- Important to monitor vital signs (VS) and implement cardiac monitoring.
- Monitor potassium (K+) and glucose levels.
- Be aware of potential apnea occurring within the first hour of infusion.
- Regularly assess neurovascular status, ensuring patient is awake and alert.
- Keep an eye on urine output and pressure.
Patient Teaching
- Inform patients of serious interactions with alcohol, emphasizing the importance of avoidance during treatment.
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Description
Test your knowledge on alprostadil with these flashcards. Explore its classification, therapeutic uses, and mechanisms of action. Perfect for students and healthcare professionals looking to deepen their understanding of this important medication.
