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Questions and Answers
A veterinarian is treating a dog with hypertension. Which of the following medications would be most appropriate to decrease the dog's blood pressure via vasodilation?
A veterinarian is treating a dog with hypertension. Which of the following medications would be most appropriate to decrease the dog's blood pressure via vasodilation?
- Prazosin (correct)
- Propranolol
- Timolol
- Atenolol
A horse has been administered xylazine for sedation. Which of the following drugs would be the MOST appropriate choice to reverse the effects of xylazine?
A horse has been administered xylazine for sedation. Which of the following drugs would be the MOST appropriate choice to reverse the effects of xylazine?
- Dexmedetomidine
- Atipamezole
- Detomidine
- Yohimbine (correct)
Following the administration of medetomidine to a canine patient, the veterinarian wants to reverse its effects. Which of the following medications is MOST appropriate?
Following the administration of medetomidine to a canine patient, the veterinarian wants to reverse its effects. Which of the following medications is MOST appropriate?
- Prazosin
- Atipamezole (correct)
- Yohimbine
- Acepromazine
A client's dog has been diagnosed with a cardiac arrhythmia. Which of the following beta-blockers would be MOST appropriate for treating this condition?
A client's dog has been diagnosed with a cardiac arrhythmia. Which of the following beta-blockers would be MOST appropriate for treating this condition?
A veterinarian needs to prescribe a medication to calm an anxious dog before a long car ride. Which class of drug is MOST appropriate for this purpose?
A veterinarian needs to prescribe a medication to calm an anxious dog before a long car ride. Which class of drug is MOST appropriate for this purpose?
A dog has been started on phenobarbital for seizure control. How often should the dog's blood levels be checked initially to ensure the drug is within the therapeutic range?
A dog has been started on phenobarbital for seizure control. How often should the dog's blood levels be checked initially to ensure the drug is within the therapeutic range?
A dog is being treated with potassium bromide for seizures. After a dosage adjustment, when should the veterinarian recheck the blood levels of the drug to ensure therapeutic efficacy?
A dog is being treated with potassium bromide for seizures. After a dosage adjustment, when should the veterinarian recheck the blood levels of the drug to ensure therapeutic efficacy?
Which of the following is a POTENTIAL side effect associated with potassium bromide use in dogs?
Which of the following is a POTENTIAL side effect associated with potassium bromide use in dogs?
Why is potassium bromide generally NOT recommended for use in cats?
Why is potassium bromide generally NOT recommended for use in cats?
A dog is experiencing toxin-induced seizures. Which of the following medications is MOST appropriate for controlling these seizures?
A dog is experiencing toxin-induced seizures. Which of the following medications is MOST appropriate for controlling these seizures?
Which of the following best describes the mechanism of action of diazepam?
Which of the following best describes the mechanism of action of diazepam?
A veterinarian wants to use a medication that provides sedation and also acts as an anti-emetic. Which of the following drugs would be MOST appropriate?
A veterinarian wants to use a medication that provides sedation and also acts as an anti-emetic. Which of the following drugs would be MOST appropriate?
Which of the listed drugs is an alpha-2 agonist primarily used for sedation?
Which of the listed drugs is an alpha-2 agonist primarily used for sedation?
A veterinarian administers dexmedetomidine to a dog. What consideration should be taken into account when calculating the appropriate dosage?
A veterinarian administers dexmedetomidine to a dog. What consideration should be taken into account when calculating the appropriate dosage?
Which of the following best describes the mechanism of action of alpha-2 agonists?
Which of the following best describes the mechanism of action of alpha-2 agonists?
A veterinarian notes that a patient is experiencing respiratory depression following anesthesia. Which of the following medications would be MOST appropriate to stimulate the respiratory center?
A veterinarian notes that a patient is experiencing respiratory depression following anesthesia. Which of the following medications would be MOST appropriate to stimulate the respiratory center?
An elderly cat is experiencing appetite loss. Which of the following drugs can be used as an appetite stimulant in cats?
An elderly cat is experiencing appetite loss. Which of the following drugs can be used as an appetite stimulant in cats?
A dog is administered acepromazine before a surgical procedure. What is the PRIMARY intended effect of this medication?
A dog is administered acepromazine before a surgical procedure. What is the PRIMARY intended effect of this medication?
Which drug is LEAST likely to be used to promote vasodilation in a patient?
Which drug is LEAST likely to be used to promote vasodilation in a patient?
A veterinarian is treating a dog with cardiac disease and needs to reduce both heart rate and blood pressure. Which medication class is MOST appropriate?
A veterinarian is treating a dog with cardiac disease and needs to reduce both heart rate and blood pressure. Which medication class is MOST appropriate?
Which drug is MOST likely to cause significant respiratory depression as a primary effect?
Which drug is MOST likely to cause significant respiratory depression as a primary effect?
A veterinarian wishes to induce vomiting in a dog that ingested a toxic substance. Which of the following medications has emetic properties due to its action as an alpha-2 agonist?
A veterinarian wishes to induce vomiting in a dog that ingested a toxic substance. Which of the following medications has emetic properties due to its action as an alpha-2 agonist?
What property is unique to detomidine, compared to xylazine, when the two drugs are used for sedation?
What property is unique to detomidine, compared to xylazine, when the two drugs are used for sedation?
A dog started on phenobarbital for seizure control begins to exhibit signs of liver dysfunction after several months. What adjustments to the treatment plan would be MOST appropriate?
A dog started on phenobarbital for seizure control begins to exhibit signs of liver dysfunction after several months. What adjustments to the treatment plan would be MOST appropriate?
A veterinarian is considering different anti-anxiety medications for a cat with a history of asthma, which medication is the SAFEST choice?
A veterinarian is considering different anti-anxiety medications for a cat with a history of asthma, which medication is the SAFEST choice?
Which medication is LEAST likely to be used for long-term seizure management?
Which medication is LEAST likely to be used for long-term seizure management?
An animal is given an alpha-2 agonist. What is the MOST likely effect one would observe?
An animal is given an alpha-2 agonist. What is the MOST likely effect one would observe?
A dog is being treated concurrently with phenobarbital and potassium bromide. What is the most important consideration for the veterinarian?
A dog is being treated concurrently with phenobarbital and potassium bromide. What is the most important consideration for the veterinarian?
Which of the following drugs is LEAST likely to be used alone to treat anxiety?
Which of the following drugs is LEAST likely to be used alone to treat anxiety?
What is the MOST important monitoring parameter for a patient on long-term propranolol therapy?
What is the MOST important monitoring parameter for a patient on long-term propranolol therapy?
A veterinarian needs a medication that provides analgesia as well as sedation for a painful procedure for horses. Which of the following medications is BEST suited?
A veterinarian needs a medication that provides analgesia as well as sedation for a painful procedure for horses. Which of the following medications is BEST suited?
A veterinarian notices that a dog on long-term phenobarbital therapy has elevated liver enzymes. What change in the treatment plan would be MOST appropriate?
A veterinarian notices that a dog on long-term phenobarbital therapy has elevated liver enzymes. What change in the treatment plan would be MOST appropriate?
How does diazepam affect neurotransmitter activity in the brain?
How does diazepam affect neurotransmitter activity in the brain?
How does the route of administration of phenobarbital impact its onset of action?
How does the route of administration of phenobarbital impact its onset of action?
If you are administering pentobarbital to a patient, what route is MOST appropriate?
If you are administering pentobarbital to a patient, what route is MOST appropriate?
A horse is given Dormosedan. The user knows that this drug results in better analgesia than Xylazine. What receptor does this drug bind to?
A horse is given Dormosedan. The user knows that this drug results in better analgesia than Xylazine. What receptor does this drug bind to?
Which of the following medications is frequently used to treat glaucoma?
Which of the following medications is frequently used to treat glaucoma?
Upon administration of an alpha-2 agonist, what effect would likely be observed?
Upon administration of an alpha-2 agonist, what effect would likely be observed?
Which of the following medications requires monitoring of drug blood levels approximately 8 weeks after starting the medication or after a dose change?
Which of the following medications requires monitoring of drug blood levels approximately 8 weeks after starting the medication or after a dose change?
Which drug is contraindicated for use in cats because it may cause an asthma-like lung condition in approximately one-third of patients?
Which drug is contraindicated for use in cats because it may cause an asthma-like lung condition in approximately one-third of patients?
What is the primary mechanism of action of Doxapram, and what condition is it most often used to treat?
What is the primary mechanism of action of Doxapram, and what condition is it most often used to treat?
Which class of drugs is MOST likely to be used as both an anti-anxiety medication and an appetite stimulant, particularly in cats?
Which class of drugs is MOST likely to be used as both an anti-anxiety medication and an appetite stimulant, particularly in cats?
A client is prescribed timolol eye drops for their dog. What condition does this dog MOST likely have.
A client is prescribed timolol eye drops for their dog. What condition does this dog MOST likely have.
Flashcards
Alpha Blockers
Alpha Blockers
Cause vasodilation and decrease blood pressure.
Phenoxybenzamine
Phenoxybenzamine
Vasodilator used to treat hypertension.
Prazosin
Prazosin
Vasodilator used to treat heart failure and hypertension.
Acepromazine
Acepromazine
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Droperidol
Droperidol
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Yohimbine
Yohimbine
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Atipamezole
Atipamezole
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Beta Blockers
Beta Blockers
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Propranolol
Propranolol
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Atenolol
Atenolol
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Timolol
Timolol
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Tranquilizer
Tranquilizer
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Sedative
Sedative
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Anti-anxiety
Anti-anxiety
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Phenobarbital Monitoring
Phenobarbital Monitoring
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Phenobarbital Safety and Monitoring
Phenobarbital Safety and Monitoring
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Potassium Bromide Monitoring
Potassium Bromide Monitoring
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Potassium Bromide Safety
Potassium Bromide Safety
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Diazepam Mechanism of Action
Diazepam Mechanism of Action
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Phenobarbital Description
Phenobarbital Description
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Potassium Bromide (KBr) Use and Caution
Potassium Bromide (KBr) Use and Caution
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Pentobarbital
Pentobarbital
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Phenothiazine Derivatives Uses
Phenothiazine Derivatives Uses
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Diazepam (Valium®) Use
Diazepam (Valium®) Use
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Zolazepam (Telazol®) Use
Zolazepam (Telazol®) Use
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Midazolam Use
Midazolam Use
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Xylazine Reversal Agents
Xylazine Reversal Agents
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Alpha-2 Agonists Use
Alpha-2 Agonists Use
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Alpha-2 Agonists Mechanism
Alpha-2 Agonists Mechanism
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Detomidine (Dormosedan®)
Detomidine (Dormosedan®)
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Dexmedetomidine (Dexdomitor®)
Dexmedetomidine (Dexdomitor®)
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Doxapram
Doxapram
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Study Notes
Alpha Blockers
- Cause vasodilation and decrease blood pressure.
- Phenoxybenzamine is a vasodilator used to treat hypertension.
- Prazosin is a vasodilator that treats heart failure and hypertension.
- Acepromazine is a vasodilator.
- Droperidol is a vasodilator.
- Yohimbine reverses the effects of xylazine (an alpha 2 agonist).
- Atipamezole reverses the effects of medetomidine, detomidine, and dexmedetomidine (alpha 2 agonists).
Beta Blockers
- Decrease heart rate and blood pressure.
- Propranolol treats cardiac arrhythmias and disease.
- Atenolol treats cardiac arrhythmias and disease.
- Timolol treats glaucoma.
Tranquilizers, Sedatives & Anti-Anxiety Meds
- Tranquilizers are calming and reduce anxiety and aggression.
- Sedatives decrease irritability and excitement.
- Anti-anxiety medications reduce anxiety.
Phenobarbital
- Monitor drug blood levels 3-4 weeks after starting or changing the dose, then approximately every 6 months.
- Has a lower margin of safety compared to other AEDs and can affect liver health.
- Liver function should be monitored approximately every 6 months, checking liver enzymes and proteins.
Potassium Bromide
- Drug blood levels should be monitored approximately 8 weeks after starting or changing the dose, then approximately every 6 months.
- Lower margin of safety than other AEDs, and can affect mentation, motor ability, and appetite.
Diazepam (Valium®, a benzodiazepine)
- Increases GABA (gamma-aminobutyric acid), which inhibits nerve impulse transmission.
- GABA is an inhibitory neurotransmitter.
Phenobarbital
- It is a long-acting barbiturate that can be administered PO or IV.
- Depresses the motor center of the cerebral cortex.
Potassium Bromide (KBr)
- Use as an adjunct medication
Use of Potassium Bromide in Cats
- Do NOT use in cats as it may cause an asthma-like lung condition in 1/3 of treated patients.
Pentobarbital (Nembutal®, a barbiturate)
- Used to treat toxin-induced seizures and for euthanasia.
Phenothiazine Derivatives
- Acepromazine maleate is a phenothiazine derivative.
- Used for sedation and as an anti-emetic.
Diazepam (Valium®)
- Used for anti-anxiety, anticonvulsant, muscle relaxation, and appetite stimulation (especially in older cats).
Other "-zolam" Drugs
- Zolazepam (Telazol®) is used for anti-anxiety, anticonvulsant, muscle relaxation, and appetite stimulation (especially in older cats).
- Midazolam is used for anti-anxiety, anticonvulsant, muscle relaxation, and appetite stimulation (especially in older cats).
Xylazine
- Can be reversed with yohimbine (Yobine®) and tolazoline (Tolazine®).
Alpha-2 Agonists
- Used for sedation and as an emetic.
- They bind to alpha-2 receptors and inhibit the release of the neurotransmitter norepinephrine.
Detomidine (Dormosedan®)
- Offers better analgesia than Xylazine.
Dexmedetomidine (Dexdomitor®)
- Used for sedation and analgesia in dogs (dosage via BSA) and cats.
Doxapram
- Stimulates the respiratory center in the medulla.
- Primarily used to treat respiratory depression or arrest.
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Description
Overview of alpha-blockers and beta-blockers, including their mechanisms of action and common uses, such as vasodilation and decreasing blood pressure. Also covers tranquilizers, sedatives, and anti-anxiety medications. Monitoring of phenobarbital drug levels is also discussed.