Questions and Answers
What is Alogliptin?
Beta amino acid derivative and antidiabetic drug.
What are the common generic names or trade names for Alogliptin?
What is the usual dose range for Alogliptin?
25 mg PO once daily.
How does Alogliptin work?
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What side effects are most likely to occur due to Alogliptin?
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What should nurses specifically observe for when a patient is on Alogliptin?
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What patient education should be provided regarding Alogliptin?
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What other medications might interact with Alogliptin?
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Study Notes
Alogliptin Overview
- Alogliptin is classified as a beta amino acid derivative and is an antidiabetic medication.
- Trade name for alogliptin is Nesina; it is often prescribed under this brand name.
Dosage Information
- The usual dosage for alogliptin is 25 mg taken orally once daily.
Mechanism of Action
- Acts as a competitive inhibitor of dipeptidyl peptidase (DPP-4).
- Increases incretin hormones, leading to reduced fasting and postprandial blood glucose levels.
Potential Side Effects
- Can cause serious side effects including hepatotoxicity and pancreatitis.
- Risk of life-threatening reactions such as anaphylaxis and angioedema.
- Severe skin reactions may occur, including Stevens-Johnson syndrome.
Nursing Considerations
- Monitor patients for signs and symptoms of hypoglycemia and pancreatitis.
- Regularly assess skin for rashes and monitor hemoglobin A1c levels before and during therapy.
- Evaluate renal function prior to and throughout treatment.
Patient Education
- Explain the importance of adhering to prescribed diet and exercise alongside medication.
- Educate about recognizing symptoms of hypoglycemia and hyperglycemia.
- Instruct on proper testing procedures for blood glucose and ketones.
- Advise to discontinue use if hypersensitivity reactions manifest.
Drug Interactions
- Caution when using alogliptin with insulin and sulfonylureas, as this combination increases the risk of hypoglycemia.
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Description
Test your knowledge on Alogliptin with these flashcards. Learn important details such as its classification, common names, dosing, and mechanism of action. Perfect for nursing or pharmacy students looking to solidify their understanding of this antidiabetic medication.
