Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

Alkaline Phosphatase Isoforms and Tissue Distribution

12 Questions

0 Views

Alkaline Phosphatase Isoforms and Tissue Distribution

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the major advantage of using osteocalcin as a marker?

It is elevated in pregnant women

It follows a circadian rhythm

It is a specific marker of liver disease

It reflects expected changes in bone formation (correct)

Which tissues contribute to alkaline phosphatase activity in the body?

Osteoclasts and fibroblasts

Osteoblasts and odontoblasts

Adipocytes and muscle cells

Liver, bone, and placenta (correct)

What is the main difference between bone and liver isoforms of alkaline phosphatase?

Different molecular weights

Different amino acid sequences

Different colors under a microscope

Different glycosylation patterns (correct)

When are the highest levels of osteocalcin observed during the menstrual cycle?

During the luteal phase Signup and view all the answers

Which cells synthesize osteocalcin in the body?

Mature osteoblasts, odontoblasts, and hypertrophic chondrocytes Signup and view all the answers

What characterizes the circadian rhythm of osteocalcin levels?

Highest levels after midnight Signup and view all the answers

What is a limitation associated with the use of osteocalcin as a bone turnover marker?

It has a short half-life Signup and view all the answers

Why is measuring P1NP preferred over P1CP as a marker of bone formation in osteoporosis?

P1NP is more stable Signup and view all the answers

Why is urinary calcium no longer commonly used to assess bone resorption?

It is influenced by various factors Signup and view all the answers

What is the main component of bone tissue that reflects high values in morning samples?

Bone mineral Signup and view all the answers

Why was the collagen-derived assay using urinary hydroxyproline considered lacking specificity and sensitivity?

It was derived from various collagen sources Signup and view all the answers

Why is procollagen type I N-terminus considered a reliable marker of bone formation?

It is more stable than C-terminal propeptides Signup and view all the answers