Alfuzosin Overview and Mechanism of Action
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Questions and Answers

What is another name for Alfuzosin?

  • Uroxatral (correct)
  • Dutasteride
  • Tamsulosin
  • Finasteride
  • What classification does Alfuzosin fall under?

    Urinary tract antispasmodic

    What is the primary indication for the use of Alfuzosin?

    Management of symptomatic benign prostatic hyperplasia (BPH)

    What is the pregnancy category of Alfuzosin?

    <p>Pregnancy category B</p> Signup and view all the answers

    What is the mechanism of action of Alfuzosin?

    <p>Selectively blocks alpha 1-adrenergic receptors in the lower urinary tract to relax smooth muscle in the bladder neck and prostate.</p> Signup and view all the answers

    What are the therapeutic effects of Alfuzosin?

    <p>Increase urine flow and decrease symptoms of BPH</p> Signup and view all the answers

    What are some common adverse reactions or side effects of Alfuzosin?

    <p>Dizziness, fatigue, headache, erectile dysfunction, priapism, postural hypotension</p> Signup and view all the answers

    Study Notes

    Alfuzosin Overview

    • Also known as Uroxatral, a medication used in urological conditions.

    Classification

    • Classified as a urinary tract antispasmodic, utilized for its relaxing effects on the urinary system.

    Indication

    • Primarily indicated for managing symptomatic benign prostatic hyperplasia (BPH), a common condition in older men that involves enlargement of the prostate gland.

    Pregnancy Category

    • Categorized as Pregnancy Category B, indicating no proven risk in humans, although studies in pregnant women are limited.

    Mechanism of Action

    • Works by selectively blocking alpha-1 adrenergic receptors in the lower urinary tract, leading to the relaxation of smooth muscle in the bladder neck and prostate, which helps alleviate urinary symptoms.

    Therapeutic Effects

    • Increases urine flow and reduces symptoms associated with BPH, improving overall urinary function and quality of life for patients.

    Adverse Reactions / Side Effects

    • Common CNS effects include dizziness, fatigue, and headache.
    • May cause intra-operative floppy iris syndrome during cataract surgery.
    • Respiratory effects include bronchitis, sinusitis, and pharyngitis.
    • Cardiovascular side effects may lead to postural hypotension.
    • Gastrointestinal issues include abdominal pain, constipation, dyspepsia, and nausea.
    • Genitourinary side effects can involve erectile dysfunction and priapism.
    • Potential hematological reaction: thrombocytopenia, a reduction in platelet count.

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    Description

    This quiz covers the essential aspects of Alfuzosin, a medication primarily used for managing benign prostatic hyperplasia (BPH). It includes its classification, indications, mechanism of action, therapeutic effects, and pregnancy category. Test your knowledge on how Alfuzosin works and its impact on urinary health.

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