4 Questions
What are the primary features used to define aggressive periodontitis?
Non‐contributory medical history, rapid attachment loss and bone destruction, familial aggregation of cases.
What are the secondary features associated with aggressive periodontitis?
Inconsistent plaque levels, elevated levels of Actinobacillus actinomycetemcomi- tans and Porphyromonas gingivalis in some populations, phagocyte abnormalities, hyper‐responsive macrophage phenotype, elevated prostaglandin (PG)‐E2, interleukin (IL)‐1 beta, self-arresting progression of attachment and bone loss.
How is aggressive periodontitis classified according to the 1999 International Workshop for Classification of Periodontal Diseases and Conditions?
It can be classified into localised aggressive periodontitis (LAP) and generalised aggressive periodontitis (GAP).
What are the characteristics of localised aggressive periodontitis?
Circumpubertal onset, localised first molar/incisor presentation with interproximal attachment loss on at least two permanent teeth, one of which is a first molar and involving no more than two teeth other than the first molars and incisors, robust serum antibody response to infecting agents.
Study Notes
Aggressive Periodontitis
- Defined by primary and secondary features (Lang et al., 1999)
Primary Features
- Non-contributory medical history, excluding systemic diseases
- Rapid attachment loss and bone destruction
- Familial aggregation of cases
Secondary Features
- Amount of plaque is inconsistent with disease severity
- Elevated levels of Actinobacillus actinomycetemcomitans (AA) and Porphyromonas gingivalis (PG) in some populations
- Phagocyte abnormalities
- Hyper-responsive macrophage phenotype
- Elevated prostaglandin (PG)-E2 and interleukin (IL)-1 beta in response to bacterial endotoxins
- Progression of attachment and bone loss may be self-arresting
Classification
- Classified into two main categories: localised aggressive periodontitis (LAP) and generalised aggressive periodontitis (GAP) (Armitage, 1999)
Localised Aggressive Periodontitis (LAP)
- Circumpubertal onset
- Localised first molar/incisor presentation with interproximal attachment loss on at least two permanent teeth
- One of the affected teeth is a first molar and involves no more than two teeth other than the first molars and incisors
- Robust serum antibody response to infecting agents
Test your knowledge of the primary and secondary features used to define aggressive periodontitis according to Lang et al.'s criteria. This quiz will assess your understanding of non-contributory medical history, rapid attachment loss and bone destruction, familial aggregation of cases, and the inconsistency between plaque and severity of the disease.
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