Aggrastat Medical Terminology
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Questions and Answers

Which of the following is an indication for Aggrastat?

  • Treating unstable angina (correct)
  • Treating stable angina
  • Preventing headaches
  • Treating stomach ulcers

Aggrastat can be used in patients who have had a stroke in the past 30 days.

False (B)

What is the mechanism of action of Aggrastat?

It inhibits platelet aggregation.

What are the trade and generic names for Aggrastat?

<p>Trade name: Aggrastat, Generic name: tirofiban</p> Signup and view all the answers

The recommended dosage of Aggrastat is intravenously _____ mcg/kg IV infused within 5 min.

<p>25</p> Signup and view all the answers

How is Aggrastat administered?

<p>Intravenous</p> Signup and view all the answers

Match the following adverse reactions with Aggrastat:

<p>Bleeding = Common side effect Pelvic pain = Possible side effect Dizziness = Possible side effect Low platelet count = Possible side effect</p> Signup and view all the answers

What is the drug classification of Aggrastat?

<p>Antiplatelet named glycoprotein IIb/IIIa inhibitors</p> Signup and view all the answers

Study Notes

Indications

  • Utilized for treating unstable angina and specific types of heart attacks.
  • Commonly administered alongside heparin for enhanced therapeutic effect.

Contraindications

  • Not suitable for individuals with a history of stroke, bleeding complications, or major surgery within the past 30 days.
  • Avoid use in patients with aneurysms, bleeding or clotting disorders, brain tumors, aortic tears, severe hypertension, or those on similar medications.
  • Previous clotting issues from Aggrastat also contraindicate its use.

Mechanism of Actions

  • Functions as a blood thinner by inhibiting platelet aggregation.
  • Efficacy is dose and concentration-dependent.

Both Trade and Generic Name

  • Trade name: Aggrastat
  • Generic name: tirofiban

Dosage

  • Initial dosage: 25 mcg/kg IV infusion within 5 minutes.
  • Maintenance: 0.15 mcg/kg/min IV infusion for up to 18 hours.
  • Adjust dosage to 0.075 mcg/kg/min IV if creatinine levels are less than 60, after the first 5 minutes.

Administration

  • Administered via intravenous (IV) route.

Adverse Reactions and Side Effects

  • Potential side effects include bleeding, pelvic pain, coronary artery dissection, dizziness, lower extremity pain, edema, sweating, and thrombocytopenia (low platelet count).

Drug Classification

  • Classified as an antiplatelet agent, specifically a glycoprotein IIb/IIIa inhibitor.

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Description

This quiz covers essential medical terminology related to Aggrastat, including indications and contraindications. Test your knowledge on when this medication should and should not be used, focusing on heart attack treatments and safety precautions.

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