Podcast
Questions and Answers
Which bacterial RNA synthesis inhibitor specifically interferes with the β subunit of the RNA polymerase?
Which bacterial RNA synthesis inhibitor specifically interferes with the β subunit of the RNA polymerase?
- Ciprofloxacin
- Doxycycline
- Rifampicin (correct)
- Amoxicillin
What is the primary mechanism of action of agents that inhibit the 30S ribosomal subunit in bacteria?
What is the primary mechanism of action of agents that inhibit the 30S ribosomal subunit in bacteria?
- Interfering with folic acid synthesis
- Preventing DNA replication
- Promoting cell division
- Interfering with the initiation process of protein synthesis (correct)
Which antibiotic interferes with folic acid metabolism as a mechanism to inhibit the survival of microorganisms?
Which antibiotic interferes with folic acid metabolism as a mechanism to inhibit the survival of microorganisms?
- Vancomycin
- Erythromycin
- Trimethoprim (correct)
- Penicillin
What type of resistance is acquired due to constant exposure to antimicrobial drugs over time?
What type of resistance is acquired due to constant exposure to antimicrobial drugs over time?
How does the acquisition of resistance through transformation occur in bacteria?
How does the acquisition of resistance through transformation occur in bacteria?
What is the main mechanism of action of β-lactam antibiotics like penicillins and cephalosporins?
What is the main mechanism of action of β-lactam antibiotics like penicillins and cephalosporins?
Which class of antibiotics is known to be cationic and includes polymyxin B and colistimethate?
Which class of antibiotics is known to be cationic and includes polymyxin B and colistimethate?
Which enzyme essential for DNA synthesis do agents inhibiting DNA topoisomerases target?
Which enzyme essential for DNA synthesis do agents inhibiting DNA topoisomerases target?
What is the main effect of aminoglycosides on ribosomes in protein synthesis?
What is the main effect of aminoglycosides on ribosomes in protein synthesis?
Which bacterial ribosomal subunit is targeted by tetracycline antibiotics?
Which bacterial ribosomal subunit is targeted by tetracycline antibiotics?
Chloramphenicol, macrolides, and lincosamides are known to inhibit which specific process in protein synthesis?
Chloramphenicol, macrolides, and lincosamides are known to inhibit which specific process in protein synthesis?
What is transferred through the sex pilus during conjugation?
What is transferred through the sex pilus during conjugation?
How do Gram-negative bacteria prevent antibiotics from reaching their cellular target?
How do Gram-negative bacteria prevent antibiotics from reaching their cellular target?
Which mechanism of antimicrobial resistance involves bacteria producing proteins structurally similar to antibiotic target sites?
Which mechanism of antimicrobial resistance involves bacteria producing proteins structurally similar to antibiotic target sites?
How does drug modification or inactivation lead to antibiotic resistance?
How does drug modification or inactivation lead to antibiotic resistance?
Which type of antibiotic resistance mechanism involves alterations in the structure of target sites?
Which type of antibiotic resistance mechanism involves alterations in the structure of target sites?
In antibiotic resistance, what does overproduction or bypass of target enzyme allow the organism to do?
In antibiotic resistance, what does overproduction or bypass of target enzyme allow the organism to do?