18 Questions
What was a significant limitation of the early use of antimonials as schistosomicides?
Toxicity
Which group discovered Niridazole and in what year?
Lambert & co-workers, 1964
What is the impact of Niridazole on carbohydrate metabolism in schistosomes?
Speeds up the breakdown of glycogen
Why is Niridazole contraindicated in pregnancy?
Can cause teratogenic effects
What makes Praziquantel a breakthrough in antischistosomal treatment?
Safety, efficacy, and broad spectrum activity
Which group of schistosomes is effectively targeted by Praziquantel?
Schistosoma species affecting humans
What is the vector for Trypanosoma cruzi, the parasite that causes Chagas disease?
Sandfly
Which of the following symptoms is NOT associated with Trypanosoma infection?
Cough
Which class of drugs includes melarsoprol, a medication commonly used against African trypanosomiasis?
Organic arsenicals
How is Trypanosoma infection typically transmitted to humans?
Through a tsetse fly bite
Which form of African sleeping sickness is caused by Trypanosoma gambiense?
Central and Western African form
What is the primary target of drugs like pentamidine used in the treatment of Trypanosoma infections?
Parasite's nervous system
What is the main reason why melarsoprol's application as a trypanocidal agent is limited?
High toxicity causing potentially fatal reactive encephalopathy
Which of the following is NOT one of the three major species of Schistosoma that infect humans?
Schistosoma cardiaca
What is the main route of infection for Schistosoma parasites in humans?
Penetration through the skin
What is an important measure for host and vector control in combating Schistosomiasis?
Provision of clean water supply
What are the qualities of an ideal anti-schistosomal agent mentioned in the text?
Absence of side effects and toxicity in humans
Which of the following is NOT an example of a molluscicide used against the snail host of Schistosoma parasites?
Diethylcarbamazine
Test your knowledge on the adverse reactions caused by melarsoprol, a trivalent arsenical compound used as a trypanocidal agent, and antischistosomal agents. Learn about the toxic effects of arsenic and the antidote for its toxicity. Explore the introduction to Schistosomiasis, also known as Bilharziasis.
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