Adverse Reactions to Food: Allergies and Intolerances

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What percentage of the population alters their diet because of adverse reactions to food?

20%

What are the body systems that might be affected by adverse reactions to food?

Digestive tract, respiratory systems, and skin

What is an adverse immune-mediated reaction to a food protein or hapten?

Food allergy

What is the term for food allergies and intolerances that result in distressing symptoms and adverse health effects?

<p>Adverse Reactions to Food (ARF)</p> Signup and view all the answers

What is the term for a small molecule that can elicit an immune response only when attached to a large carrier protein?

<p>Hapten</p> Signup and view all the answers

What is an example of a food that can cause a life-threatening anaphylaxis in some individuals?

<p>Peanuts</p> Signup and view all the answers

What happens when the tolerated level of histamine in the body is exceeded?

<p>Symptoms of excessive histamine develop</p> Signup and view all the answers

What is a common characteristic of people who are more sensitive to histamine?

<p>They have a genetically determined inability to catabolize histamine</p> Signup and view all the answers

Which of the following foods is NOT high in histamine content?

<p>Pineapples</p> Signup and view all the answers

What is a reason for an excessive reaction to histamine in histamine intolerance?

<p>A deficiency of the enzymes that deactivate histamine</p> Signup and view all the answers

What is the role of food allergy or intolerance in certain disorders?

<p>It is emerging as a potential contributing factor in various disorders</p> Signup and view all the answers

What is the first step in diagnosing adverse reactions to food?

<p>Taking a detailed clinical history</p> Signup and view all the answers

What can biochemical tests rule out in diagnosing adverse reactions to food?

<p>Nonallergenic causes of symptoms</p> Signup and view all the answers

What is necessary to confirm a diagnosis of adverse reactions to food?

<p>Proof that the food causes an adverse response and verification of an immune or non-immune-mediated response</p> Signup and view all the answers

What is the purpose of plotting anthropometric measurements on a growth chart?

<p>To assess the overall growth and development of infants and children</p> Signup and view all the answers

What is the main purpose of a 7- to 14-day food and symptom record?

<p>To identify possible nutrient insufficiencies and deficiencies</p> Signup and view all the answers

What is the purpose of an elimination diet?

<p>To eliminate suspect foods from the diet for a specified period</p> Signup and view all the answers

What is the purpose of a food and symptom record during an elimination diet?

<p>To ensure all forms of suspected foods have been eliminated</p> Signup and view all the answers

What is the purpose of reintroducing foods into the diet during an elimination diet?

<p>To determine any adverse reactions to foods</p> Signup and view all the answers

What may be used for additional nutrition support in adults on an elimination diet?

<p>Elemental formulas, medical foods, or hypoallergenic formulas</p> Signup and view all the answers

What should be considered if symptoms persist with careful avoidance of suspect foods?

<p>Other causes for the symptoms</p> Signup and view all the answers

What is the purpose of personalizing an elimination diet?

<p>To tailor the diet to an individual's needs</p> Signup and view all the answers

What is the condition for excluding a food from the diet?

<p>A positive result on a skin prick test or allergen-specific IgE blood test</p> Signup and view all the answers

When is an oral food challenge conducted?

<p>Once symptoms have resolved and the person is not taking any medications</p> Signup and view all the answers

Why is the form of the food ingested an important consideration in the nutritional assessment of ARFs?

<p>Because some people may tolerate baked forms of proteins but not the unbaked form</p> Signup and view all the answers

What should be listed on food labels?

<p>The top eight allergens and their specific types</p> Signup and view all the answers

Why is restoring gut health important in managing allergic responses?

<p>Because 70% of immune cells are located in the gut-associated lymphatic tissue</p> Signup and view all the answers

What is an important measure to restore gut health?

<p>Optimizing stomach acidity and enzyme function</p> Signup and view all the answers

Why is it important to monitor nutritional adequacy?

<p>To evaluate the patient's nutritional status and food and symptom records</p> Signup and view all the answers

What should be conducted regularly to monitor nutritional adequacy?

<p>An ongoing evaluation of the patient's nutritional status and food and symptom records</p> Signup and view all the answers

What is the current understanding about delaying the introduction of foods to prevent atopic disease?

<p>There is no convincing evidence that delaying introduction prevents atopic disease</p> Signup and view all the answers

Which nutrients have been cited as potential influences on the development of allergy?

<p>Vitamin A, vitamin D, omega-3 fatty acids, and folate</p> Signup and view all the answers

What type of diets may prevent the development of food allergies?

<p>Diets high in antioxidants and phytonutrients</p> Signup and view all the answers

What has been proposed as a possible contributor to the increase in food allergy in children?

<p>Vitamin D deficiency</p> Signup and view all the answers

What is the potential role of folate in the development of asthma and allergy?

<p>Folate deficiency is associated with an increased risk of asthma and allergy</p> Signup and view all the answers

What is the potential benefit of maternal consumption of fish oil in pregnancy?

<p>It protects against the development of asthma, eczema, and allergic sensitization</p> Signup and view all the answers

What is the definition of probiotics?

<p>Live microorganisms that impart health benefits</p> Signup and view all the answers

What is the relationship between maternal antioxidant status in pregnancy and cord blood immune responses?

<p>There is a positive correlation between the two</p> Signup and view all the answers

Study Notes

Adverse Reactions to Food (ARF)

  • Encompass food allergy and intolerance, with growing prevalence and implicated in chronic disorders like asthma and autoimmune diseases.
  • 20% of the population alters their diet due to ARF, affecting digestive tract, respiratory systems, and skin.
  • Food allergy or hypersensitivity is an adverse immune-mediated reaction to a food, usually a protein or hapten.

Definitions

  • Adverse Reactions to Food (ARF): Food allergies and intolerances that result in distressing symptoms and adverse health effects.
  • Food Allergy: Hypersensitivity, adverse immune-mediated reaction to food, usually a protein or hapten.

Histamine Intolerance

  • Some people are more sensitive to histamine due to a genetically determined inability to catabolize or break down histamine.
  • Foods with high histamine content include fermented foods, tomatoes, strawberries, sauerkraut, aged cheeses, processed meats and fish, alcoholic beverages, and leftovers.

Unclear Adverse Reactions

  • The role of food allergy or intolerance in behavioral disorders, neurologic disorders, musculoskeletal disorders, irritable bowel syndrome, and other clinical conditions is emerging.

Assessment

  • Diagnosis of ARFs requires identification of the suspected food or food ingredient, proof that the food causes an adverse response, and verification of an immune or non-immune-mediated response.
  • The first diagnostic tool is a detailed clinical history, followed by appropriate testing, biochemical tests, and anthropometric measurements.

MNT (Medical Nutrition Therapy)

  • A 7- to 14-day food and symptom record is useful for uncovering ARFs and identifying possible nutrient insufficiencies and deficiencies.

Food Elimination Diet

  • Suspect foods are eliminated from the diet for a specified period, usually 4 to 12 weeks, followed by a reintroduction and food-challenge phase.
  • Elimination diets should be personalized and used to screen for allergies.

Nutritional Adequacy

  • The nutritional adequacy of the diet should be monitored on a regular basis by conducting an ongoing evaluation of the patient's nutritional status and food and symptom records.

Prevention of Food Allergies

  • Nutrients such as vitamin A, vitamin D, omega-3 fatty acids, folate, and other micronutrients have been cited as potential influences on the development of allergy.
  • Antioxidants, vitamin D, folate, and PUFA (polyunsaturated fatty acids) may prevent the development of food allergies.

Healing the Gut and Restoring Immune Balance

  • Restoring gut health should improve immune function and modulate allergic responses.
  • Measures include eliminating problematic foods, optimizing stomach acidity and enzyme function, identifying and treating pathogens, restoring intestinal barrier function, and repleting nutritional status.

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