Adverse Effects of Deltamethrin Quiz
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Questions and Answers

What is a potential skin-related adverse effect associated with the use of deltammophene?

  • Liver injury
  • Blistering of skin and membranes (correct)
  • Cough suppression
  • Euphoria

    • Which condition is specifically associated with skin reactions to certain medications?

  • Salicylism
  • Euphoria
  • Biliary colic
  • Stevens-Johnson syndrome (correct)

    • For optimal absorption and reduced gastric upset, which is the recommended way to take oral NSAIDs?

  • Crushed or chewed
  • With alcohol
  • With food, milk, or a glass of water (correct)
  • On an empty stomach

    • What is a characteristic effect of mu opioid receptors?

    <p>Physical dependence</p> Signup and view all the answers

    Which of the following is a side effect of opioids related to gastrointestinal function?

    <p>Decreased GI mobility</p> Signup and view all the answers

    What must not be done with enteric-coated or sustained-release opioid formulations?

    <p>Crush or chew them</p> Signup and view all the answers

    What potential condition could occur if someone misuses opioids?

    <p>Respiratory depression</p> Signup and view all the answers

    Which of these symptoms is NOT commonly associated with opioid use?

    <p>Muscle spasms</p> Signup and view all the answers

    What defines pain according to Margo McCaffery?

    <p>An experience that is subjective, as verified by the individual.</p> Signup and view all the answers

    Which type of pain is typically associated with surgery, trauma, or acute illness?

    <p>Nociceptive pain</p> Signup and view all the answers

    Which of the following is a cause of chronic pain?

    <p>Fibromyalgia</p> Signup and view all the answers

    What is the term used to describe pain associated with potential tissue damage?

    <p>Nociceptive pain</p> Signup and view all the answers

    What type of pain results from changes in nerve function and transmission over time?

    <p>Neuropathic pain</p> Signup and view all the answers

    Which assessment is crucial in pain management?

    <p>Assessing the patient's pain history</p> Signup and view all the answers

    Which statement best describes acute pain?

    <p>Short-term pain often associated with injury.</p> Signup and view all the answers

    Which of these conditions is typically classified under procedural pain?

    <p>Post-surgical pain</p> Signup and view all the answers

    Which patient group should avoid acetaminophen during CABG surgery?

    <p>Patients with existing heart disease</p> Signup and view all the answers

    What is a significant interaction concern when using acetaminophen?

    <p>Interacts with warfarin</p> Signup and view all the answers

    Which property is NOT associated with acetaminophen?

    <p>Anti-inflammatory properties</p> Signup and view all the answers

    What is the effect of alcohol on acetaminophen metabolism?

    <p>Induces a toxic metabolite</p> Signup and view all the answers

    What symptom is NOT typically associated with acetaminophen overdose?

    <p>Headache</p> Signup and view all the answers

    What should patients avoid doing with sustained release or controlled release products?

    <p>Crushing or chewing the products</p> Signup and view all the answers

    Why should patients with a sulfa allergy avoid acetaminophen?

    <p>Potential cross-reactivity</p> Signup and view all the answers

    Which pathway becomes more significant during acetaminophen overdose?

    <p>Minor pathway</p> Signup and view all the answers

    How is physical dependence different from opioid use disorder?

    <p>Opioid use disorder includes psychological dependence</p> Signup and view all the answers

    What is a true statement regarding the inhibition of COX-1 and COX-2 by acetaminophen?

    <p>It weakly inhibits both in the CNS</p> Signup and view all the answers

    What is a key feature of Patient Controlled Analgesia (PCA)?

    <p>It allows self-administration through reliable devices</p> Signup and view all the answers

    What is recommended regarding dosage adjustments for pain management medications?

    <p>Consult with a healthcare provider before making changes</p> Signup and view all the answers

    What effect does a sulfa allergy have on acetaminophen use?

    <p>Increased risk of allergic reaction</p> Signup and view all the answers

    What is one of the main concerns of acetaminophen overdose?

    <p>Acute liver failure</p> Signup and view all the answers

    Which statement best represents the characteristics of opioid misuse?

    <p>It involves drug use inconsistent with medical or social norms</p> Signup and view all the answers

    What is a severe consequence of acetaminophen overdose?

    <p>Liver injury</p> Signup and view all the answers

    Which treatment is recommended for acetaminophen overdose?

    <p>Acetylcysteine</p> Signup and view all the answers

    What daily dosage of acetaminophen is associated with a risk for liver injury?

    <p>4000mg/day</p> Signup and view all the answers

    What condition can occur with simultaneous use of acetaminophen and alcohol?

    <p>Liver disease</p> Signup and view all the answers

    What symptom may indicate an anaphylactic reaction to acetaminophen?

    <p>Swelling of the face, mouth, and throat</p> Signup and view all the answers

    Which of the following is NOT considered a common adverse effect of acetaminophen?

    <p>Gastrointestinal bleeding</p> Signup and view all the answers

    What is the primary cause of hepatitis in acetaminophen overdose?

    <p>Depletion of glutathione</p> Signup and view all the answers

    Which statement is FALSE regarding the use of acetaminophen?

    <p>It should be taken with alcohol to prevent liver damage.</p> Signup and view all the answers

    Study Notes

    • Painful rash, blistering, and detachment of skin and membranes are possible side effects.
    • Severe skin reactions include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).
    • Acute generalized exanthematous pustulosis (AGEP) can also occur with certain drugs.

    Administration Guidelines for NSAIDs

    • Take orally with food, milk, or water to minimize gastric irritation.
    • Do not crush or chew enteric-coated or sustained-release formulations.
    • Alcohol consumption is discouraged due to potential interactions.

    Opioid Receptors and Their Functions

    • Endogenous opioid peptides are distributed in the central nervous system (CNS) and peripheral tissues.
    • Mu receptors are primarily responsible for analgesia and sedation, while kappa receptors have a minor role.
    • Notable effects include cough suppression, nausea, orthostatic hypotension, miosis, and decreased GI mobility.

    Pain Management Objectives

    • Differentiate types of pain: acute (surgery, trauma) vs. chronic (nerve issues, cancer).
    • Compare various classes of pain medications and their roles in treatment.
    • Emphasize the need for appropriate patient education on medication use and pain management.

    Understanding Pain

    • Pain is a subjective experience defined by the International Association for the Study of Pain.
    • Causes of pain include surgery, injury, infection, and chronic conditions like fibromyalgia.

    Types of Pain

    • Acute pain often arises from surgical procedures or trauma, typically nociceptive in nature.
    • Chronic pain can arise from changes in nerve function and may be nociceptive or neuropathic.

    Acetaminophen Characteristics

    • Acetaminophen weakly inhibits COX-1 and COX-2 in the CNS, lacking anti-inflammatory properties.
    • It is generally safe regarding gastric irritation and renal impairment compared to NSAIDs.

    Alcohol and Acetaminophen Interaction

    • Chronic alcohol use depletes glutathione, increasing the risk of liver toxicity from acetaminophen overdose.
    • Overdose symptoms include nausea, vomiting, and can lead to hepatic failure.

    Adverse Effects of Acetaminophen

    • Doses exceeding 4000 mg/day can result in liver injury, especially with concurrent alcohol use.
    • Potential for anaphylaxis and requires gradual withdrawal from long-term use.

    Understanding Dependency and Misuse

    • Physical dependence differs from addiction; physical dependence alone does not indicate misuse.
    • Opioid use disorder is characterized by chronic disease patterns of substance pursuit for rewards.

    Patient Controlled Analgesia (PCA)

    • PCA allows patients to self-administer pain medication, enhancing recovery post-surgery.
    • Devices are programmed for preset dosages with lock-out periods to prevent overdose.

    Patient Education for Pain Management

    • Advise against increasing medication dosages without consultation and highlight the importance of gradual discontinuation for long-term use.

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    Description

    Test your knowledge on the skin-related adverse effects associated with deltamethrin, including conditions like Stevens-Johnson syndrome and toxic epidermal necrolysis. This quiz covers critical information about various skin reactions and their implications.

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