Adverse Effects of Deltamethrin Quiz

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Questions and Answers

What is a potential skin-related adverse effect associated with the use of deltammophene?

Liver injury

Blistering of skin and membranes (correct)

Cough suppression

Euphoria

Which condition is specifically associated with skin reactions to certain medications?

Salicylism

Euphoria

Biliary colic

Stevens-Johnson syndrome (correct)

For optimal absorption and reduced gastric upset, which is the recommended way to take oral NSAIDs?

Crushed or chewed

With alcohol

With food, milk, or a glass of water (correct)

On an empty stomach

What is a characteristic effect of mu opioid receptors?

Physical dependence Signup and view all the answers

Which of the following is a side effect of opioids related to gastrointestinal function?

Decreased GI mobility Signup and view all the answers

What must not be done with enteric-coated or sustained-release opioid formulations?

Crush or chew them Signup and view all the answers

What potential condition could occur if someone misuses opioids?

Respiratory depression Signup and view all the answers

Which of these symptoms is NOT commonly associated with opioid use?

Muscle spasms Signup and view all the answers

What defines pain according to Margo McCaffery?

An experience that is subjective, as verified by the individual. Signup and view all the answers

Which type of pain is typically associated with surgery, trauma, or acute illness?

Nociceptive pain Signup and view all the answers

Which of the following is a cause of chronic pain?

Fibromyalgia Signup and view all the answers

What is the term used to describe pain associated with potential tissue damage?

Nociceptive pain Signup and view all the answers

What type of pain results from changes in nerve function and transmission over time?

Neuropathic pain Signup and view all the answers

Which assessment is crucial in pain management?

Assessing the patient's pain history Signup and view all the answers

Which statement best describes acute pain?

Short-term pain often associated with injury. Signup and view all the answers

Which of these conditions is typically classified under procedural pain?

Post-surgical pain Signup and view all the answers

Which patient group should avoid acetaminophen during CABG surgery?

Patients with existing heart disease Signup and view all the answers

What is a significant interaction concern when using acetaminophen?

Interacts with warfarin Signup and view all the answers

Which property is NOT associated with acetaminophen?

Anti-inflammatory properties Signup and view all the answers

What is the effect of alcohol on acetaminophen metabolism?

Induces a toxic metabolite Signup and view all the answers

What symptom is NOT typically associated with acetaminophen overdose?

Headache Signup and view all the answers

What should patients avoid doing with sustained release or controlled release products?

Crushing or chewing the products Signup and view all the answers

Why should patients with a sulfa allergy avoid acetaminophen?

Potential cross-reactivity Signup and view all the answers

Which pathway becomes more significant during acetaminophen overdose?

Minor pathway Signup and view all the answers

How is physical dependence different from opioid use disorder?

Opioid use disorder includes psychological dependence Signup and view all the answers

What is a true statement regarding the inhibition of COX-1 and COX-2 by acetaminophen?

It weakly inhibits both in the CNS Signup and view all the answers

What is a key feature of Patient Controlled Analgesia (PCA)?

It allows self-administration through reliable devices Signup and view all the answers

What is recommended regarding dosage adjustments for pain management medications?

Consult with a healthcare provider before making changes Signup and view all the answers

What effect does a sulfa allergy have on acetaminophen use?

Increased risk of allergic reaction Signup and view all the answers

What is one of the main concerns of acetaminophen overdose?

Acute liver failure Signup and view all the answers

Which statement best represents the characteristics of opioid misuse?

It involves drug use inconsistent with medical or social norms Signup and view all the answers

What is a severe consequence of acetaminophen overdose?

Liver injury Signup and view all the answers

Which treatment is recommended for acetaminophen overdose?

Acetylcysteine Signup and view all the answers

What daily dosage of acetaminophen is associated with a risk for liver injury?

4000mg/day Signup and view all the answers

What condition can occur with simultaneous use of acetaminophen and alcohol?

Liver disease Signup and view all the answers

What symptom may indicate an anaphylactic reaction to acetaminophen?

Swelling of the face, mouth, and throat Signup and view all the answers

Which of the following is NOT considered a common adverse effect of acetaminophen?

Gastrointestinal bleeding Signup and view all the answers

What is the primary cause of hepatitis in acetaminophen overdose?

Depletion of glutathione Signup and view all the answers

Which statement is FALSE regarding the use of acetaminophen?

It should be taken with alcohol to prevent liver damage. Signup and view all the answers

Study Notes

Painful rash, blistering, and detachment of skin and membranes are possible side effects.
Severe skin reactions include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).
Acute generalized exanthematous pustulosis (AGEP) can also occur with certain drugs.

Administration Guidelines for NSAIDs

Take orally with food, milk, or water to minimize gastric irritation.
Do not crush or chew enteric-coated or sustained-release formulations.
Alcohol consumption is discouraged due to potential interactions.

Opioid Receptors and Their Functions

Endogenous opioid peptides are distributed in the central nervous system (CNS) and peripheral tissues.
Mu receptors are primarily responsible for analgesia and sedation, while kappa receptors have a minor role.
Notable effects include cough suppression, nausea, orthostatic hypotension, miosis, and decreased GI mobility.

Pain Management Objectives

Differentiate types of pain: acute (surgery, trauma) vs. chronic (nerve issues, cancer).
Compare various classes of pain medications and their roles in treatment.
Emphasize the need for appropriate patient education on medication use and pain management.

Understanding Pain

Pain is a subjective experience defined by the International Association for the Study of Pain.
Causes of pain include surgery, injury, infection, and chronic conditions like fibromyalgia.

Types of Pain

Acute pain often arises from surgical procedures or trauma, typically nociceptive in nature.
Chronic pain can arise from changes in nerve function and may be nociceptive or neuropathic.

Acetaminophen Characteristics

Acetaminophen weakly inhibits COX-1 and COX-2 in the CNS, lacking anti-inflammatory properties.
It is generally safe regarding gastric irritation and renal impairment compared to NSAIDs.

Alcohol and Acetaminophen Interaction

Chronic alcohol use depletes glutathione, increasing the risk of liver toxicity from acetaminophen overdose.
Overdose symptoms include nausea, vomiting, and can lead to hepatic failure.

Adverse Effects of Acetaminophen

Doses exceeding 4000 mg/day can result in liver injury, especially with concurrent alcohol use.
Potential for anaphylaxis and requires gradual withdrawal from long-term use.

Understanding Dependency and Misuse

Physical dependence differs from addiction; physical dependence alone does not indicate misuse.
Opioid use disorder is characterized by chronic disease patterns of substance pursuit for rewards.

Patient Controlled Analgesia (PCA)

PCA allows patients to self-administer pain medication, enhancing recovery post-surgery.
Devices are programmed for preset dosages with lock-out periods to prevent overdose.

Patient Education for Pain Management

Advise against increasing medication dosages without consultation and highlight the importance of gradual discontinuation for long-term use.

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Description

Test your knowledge on the skin-related adverse effects associated with deltamethrin, including conditions like Stevens-Johnson syndrome and toxic epidermal necrolysis. This quiz covers critical information about various skin reactions and their implications.