Adverse Effects and Treatment Benefits of Methotrexate and Cyclosporine
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Questions and Answers

Which of the following should be avoided in patients with advanced or decompensated heart failure?

  • Budesonide in IBD treatment
  • Immunomodulators
  • Aminosalicylates formulations
  • Corticosteroids preparations (correct)

Why should corticosteroids be avoided in patients with advanced or decompensated heart failure?

  • To avoid exacerbation of heart failure (correct)
  • To improve kidney function
  • To prevent allergic reactions
  • To prevent blood clot formation

Which medication can potentially worsen heart failure in patients with pre-existing heart conditions?

  • Aminosalicylates formulations
  • Budesonide in IBD treatment
  • Immunomodulators
  • Corticosteroids preparations (correct)

What is a potential adverse effect of corticosteroids in patients with heart failure?

<p>Exacerbation of heart failure (C)</p> Signup and view all the answers

Among the listed medications, which one specifically poses a risk for patients with heart failure due to its potential exacerbation effect?

<p>Corticosteroids preparations (C)</p> Signup and view all the answers

Which of the following adverse effects is associated with long-term methotrexate use?

<p>Pulmonary fibrosis (A)</p> Signup and view all the answers

For which condition does cyclosporine have a short-term benefit in treatment according to the text?

<p>Inflammatory bowel disease (B)</p> Signup and view all the answers

What is the primary reason for using cyclosporine in patients with acute, severe UC as per the text?

<p>To avoid colectomy (D)</p> Signup and view all the answers

In which type of inflammatory bowel disease (IBD) does cyclosporine have little efficacy according to the text?

<p>Crohn's disease (CD) (A)</p> Signup and view all the answers

What serious adverse effect can result from long-term use of corticosteroids according to the text?

<p>Osteoporosis (C)</p> Signup and view all the answers

What type of patients are generally considered for treatment options other than ASA therapy or corticosteroids?

<p>Patients who fail ASA therapy or are refractory to corticosteroids (D)</p> Signup and view all the answers

Why might a patient be considered refractory to corticosteroids?

<p>They have developed a dependency on corticosteroids (D)</p> Signup and view all the answers

Which of the following patients would be most likely to be considered for immunomodulator therapy?

<p>A patient refractory to corticosteroids (B)</p> Signup and view all the answers

In what scenario would a healthcare provider consider using Budesonide in the treatment of IBD?

<p>For patients who fail ASA therapy or are refractory to corticosteroids (A)</p> Signup and view all the answers

What is a common adverse effect associated with prolonged use of corticosteroids?

<p>Osteoporosis (B)</p> Signup and view all the answers

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