Podcast
Questions and Answers
What was the outcome of the skin prick tests in one patient who experienced an immune-mediated reaction?
What was the outcome of the skin prick tests in one patient who experienced an immune-mediated reaction?
- Reaction only to sargramostim
- Cross-reaction between the two recombinant forms of GM-CSF (correct)
- Reaction only to filgrastim
- No reaction to both recombinant forms of GM-CSF
What was the treatment used to resolve the symptoms of a 42-year-old woman who experienced a hypersensitivity reaction to molgramostim?
What was the treatment used to resolve the symptoms of a 42-year-old woman who experienced a hypersensitivity reaction to molgramostim?
- Intravenous injection of filgrastim
- Adrenaline, hydrocortisone, and promethazine (correct)
- Glucocorticoids and antihistamines
- Desensitization protocol
What is the term used to describe the presence of pain in a specific location not spatially connected with the organ affected?
What is the term used to describe the presence of pain in a specific location not spatially connected with the organ affected?
- Hypersensitivity reaction
- Immune-mediated reaction
- Visceral organ cross-sensitization
- Referred pain (correct)
What is an example of a known relation between visceral organs and skin?
What is an example of a known relation between visceral organs and skin?
What is the explanation for the cross-talk between different DRG neurons?
What is the explanation for the cross-talk between different DRG neurons?
What is the function of the cell soma of the DRG in relation to cross-talk?
What is the function of the cell soma of the DRG in relation to cross-talk?
What is cross-sensitization defined as in the context of adverse drug reactions?
What is cross-sensitization defined as in the context of adverse drug reactions?
What is an example of a therapeutic class where class effect is observed?
What is an example of a therapeutic class where class effect is observed?
Which of the following agents are known to show cross-sensitivity?
Which of the following agents are known to show cross-sensitivity?
What is the observed frequency of anaphylactic reactions without immune-mediated mechanism in patients with testicular cancer given GM-CSF?
What is the observed frequency of anaphylactic reactions without immune-mediated mechanism in patients with testicular cancer given GM-CSF?
Which of the following agents are NOT known to show cross-sensitivity?
Which of the following agents are NOT known to show cross-sensitivity?
What is the term for the risk for adverse drug reactions shared by different agents within a narrow therapeutic class?
What is the term for the risk for adverse drug reactions shared by different agents within a narrow therapeutic class?