Advancements in Endocrinology and Diabetes Mellitus

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19 Questions

Which therapy led to a slightly greater reduction in A1C levels after 26 weeks?

Basal insulin therapy with once-weekly insulin icodec

How many adults with type 2 diabetes participated in the trial?

588

What was the mean A1C level of the participants at the beginning of the trial?

Approximately 8.6 percent

What was the estimated treatment difference in A1C reduction between the two therapies?

-0.2 percentage points

Which therapy had a slightly greater reduction in A1C levels?

Basal insulin therapy with once-weekly insulin icodec

What type of diabetes was the trial focused on?

Type 2 diabetes

What was the frequency of insulin icodec administration in the trial?

Once-weekly

What was the frequency of insulin degludec administration in the trial?

Once-weekly

What was the main outcome measure in the trial?

A1C reduction

What was the difference in the number of level 2 hypoglycemic episodes between the two therapies?

Not specified in the text

Which of the following is true about the diagnosis of adrenal insufficiency?

The morning cortisol threshold to exclude chronic adrenal insufficiency is approximately 25 to 30 percent lower with newer cortisol assays.

What is the typical use of early morning serum cortisol levels in the diagnosis of adrenal insufficiency?

To select patients for additional evaluation with corticotropin (ACTH) stimulation testing.

What is the interpretation of the serum cortisol result dependent on when evaluating patients for chronic adrenal insufficiency?

The type of assay used to measure cortisol.

What is the morning cortisol threshold to exclude chronic adrenal insufficiency with older immunoassays?

18 mcg/dL

What is the morning cortisol threshold to exclude chronic adrenal insufficiency with newer cortisol assays?

13 to 14 mcg/dL

What is the purpose of corticotropin (ACTH) stimulation testing?

To select patients for additional evaluation.

What is the influence of cortisol assay technique on the diagnosis of adrenal insufficiency?

It may lead to underdiagnosis of adrenal insufficiency.

What is the approximate percentage difference in morning cortisol threshold between older immunoassays and newer cortisol assays?

25 to 30 percent lower with newer cortisol assays

What is the unit of measurement for cortisol levels in the text?

mcg/dL

Stay up-to-date with the latest advancements in endocrinology and diabetes mellitus with this informative quiz. Test your knowledge on the newest research and developments in the field.

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