ADRs of Cardio-Selective B-Blockers and Mechanism of CCBs

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Which of the following calcium channel blockers would be most appropriate for a patient with chronic heart failure?

Verapamil (correct)

Diltiazem

Amlodipine

Nifedipine

A patient with bronchial asthma and hypertension is prescribed a calcium channel blocker. Which of the following would be contraindicated?

Amlodipine

Diltiazem

Nifedipine

Verapamil (correct)

A patient with hypertension and atrial fibrillation is prescribed a calcium channel blocker. Which combination should be avoided to prevent severe bradycardia and heart block?

Nifedipine and a beta-blocker

Diltiazem and a beta-blocker

Amlodipine and a beta-blocker

Verapamil and a beta-blocker (correct)

A patient with hypertension and angina pectoris is prescribed a calcium channel blocker. Which of the following would be most appropriate?

Diltiazem Signup and view all the answers

Which of the following adverse effects is most commonly associated with dihydropyridine calcium channel blockers, such as nifedipine and amlodipine?

Hypotension Signup and view all the answers

Which of the following is NOT a mechanism by which beta-blockers lower blood pressure?

Causing vasodilation through $\beta_2$ receptor blockade Signup and view all the answers

Which of the following beta-blockers is useful in treating anxiety and tremors associated with hyperthyroidism?

Propranolol Signup and view all the answers

Which of the following conditions is NOT an indication for the use of beta-blockers?

Hypertension with no associated cardiovascular disease Signup and view all the answers

Which of the following statements about nebivolol is TRUE?

It increases nitric oxide synthesis by stimulating the nitric oxide synthase (NOS) enzyme Signup and view all the answers

Which of the following statements about carvedilol is TRUE?

It has an $\alpha_1$-blocking action, causing vasodilation Signup and view all the answers

Which of the following is a major adverse effect of calcium channel blockers (CCBs) in patients with chronic heart failure (HF)?

Negative inotropic effect Signup and view all the answers

Which of the following antihypertensive drug classes is contraindicated in patients with hyperthyroidism-induced anxiety and tremors?

Beta-blockers Signup and view all the answers

In a patient with hypertension and atrial fibrillation (an arrhythmia), which of the following antihypertensive drug classes would be preferred?

Calcium channel blockers (non-dihydropyridine) Signup and view all the answers

In a patient with hypertension and ischemic heart disease (IHD), which of the following antihypertensive drug classes would be most appropriate as initial therapy?

Angiotensin-converting enzyme inhibitors (ACEIs) Signup and view all the answers

In a patient with hypertension and chronic kidney disease (CKD), which of the following antihypertensive drug classes should be avoided due to potential adverse effects?

Thiazide diuretics Signup and view all the answers

Which of the following is a mechanism by which calcium channel blockers (CCBs) reduce blood pressure?

Promoting peripheral vasodilation by blocking calcium entry into vascular smooth muscle cells Signup and view all the answers

Which of the following antihypertensive agents should be used with caution in patients with hyperthyroidism-induced anxiety and tremors?

Beta-blockers Signup and view all the answers

In patients with atrial fibrillation, which class of antihypertensive agents should be used cautiously to avoid potential adverse effects on cardiac conduction?

Non-dihydropyridine calcium channel blockers Signup and view all the answers

Which class of antihypertensive agents is generally avoided in patients with chronic heart failure (HF) due to their potential to worsen the condition?

Non-selective beta-blockers Signup and view all the answers

In patients with ischemic heart disease (IHD), which class of antihypertensive agents should be used with caution due to their potential to worsen myocardial oxygen supply?