Adrenergic Transmission in Pharmacology
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Questions and Answers

Which enzyme is responsible for the conversion of tyrosine to DOPA?

  • DOPA decarboxylase
  • Tyrosine hydroxylase (correct)
  • α-Methyltyrosine
  • Metyrosine
  • Which receptor subtype is primarily involved in vasoconstriction of blood vessels?

  • $\beta1$
  • $\alpha2$
  • $\beta2$
  • $\alpha1$ (correct)
  • Which adrenergic receptor subtype is primarily involved in vasodilation of the liver?

  • $\alpha1$
  • $\alpha2$
  • $\beta2$ (correct)
  • $\beta1$
  • Which enzyme is responsible for the degradation of catecholamines outside the neuronal cells?

    <p>COMT</p> Signup and view all the answers

    What is the primary neurotransmitter released from postganglionic sympathetic nerve endings?

    <p>$\text{NE}$</p> Signup and view all the answers

    Study Notes

    Catecholamine Synthesis and Degradation

    • Tyrosine is converted to DOPA by the enzyme tyrosine hydroxylase.

    Adrenergic Receptor Subtypes

    • The alpha-1 receptor subtype is primarily involved in vasoconstriction of blood vessels.
    • The beta-2 receptor subtype is primarily involved in vasodilation of the liver.

    Catecholamine Degradation

    • The enzyme catechol-O-methyltransferase (COMT) is responsible for the degradation of catecholamines outside the neuronal cells.

    Sympathetic Nerve Endings

    • The primary neurotransmitter released from postganglionic sympathetic nerve endings is norepinephrine.

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    Description

    Test your knowledge of adrenergic transmission in pharmacology with this quiz. Topics covered include the synthesis, release, and function of norepinephrine, adrenaline, and related pathways.

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