Adrenergic Drugs Ch. 19, 20 week 6

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Questions and Answers

Adrenergic drugs produce effects similar to which of the body's systems?

  • The somatic nervous system
  • The parasympathetic nervous system
  • The central nervous system
  • The sympathetic nervous system (correct)

When an adrenergic drug stimulates β₁-adrenergic receptors, the result is an increased force of contraction, which is known as what type of positive effect?

  • Inotropic (correct)
  • Adrenergic
  • Dromotropic
  • Chronotropic

When a patient is taking an adrenergic drug, the nurse expects to see which effect?

  • Increased intestinal peristalsis
  • Increased heart rate (correct)
  • Peripheral vasodilation
  • Bronchial constriction

An adrenergic agonist is ordered for a patient in shock. The nurse notes that this drug has had its primary intended effect when which condition occurs?

<p>Increased blood pressure (A)</p> Signup and view all the answers

Which condition is an indication for epinephrine (Adrenalin®)?

<p>Acute asthma attacks (B)</p> Signup and view all the answers

After a near-fatal motor vehicle accident, a family has given permission for their 6-year-old son's organs to be donated. Which medication will be given to the child to maintain the blood pressure in his organs until transplantation can be carried out?

<p>dopamine hydrochloride (D)</p> Signup and view all the answers

During rounds, the nurse is assessing a patient who is receiving dobutamine for severe heart failure. The patient reports increasing chest pain and a sensation of anxiety. Her heart rate, which was 88, is now up to 110, and her blood pressure, which was 120/68, is now 150/98. What is the nurse's immediate assessment of the patient's condition?

<p>The dobutamine may be causing a worsening of a pre-existing cardiac disorder. (B)</p> Signup and view all the answers

A 14-year-old female patient has been treated for asthma for almost 4 months. Two weeks ago, she was given salmeterol xinafoate as part of her medication regimen. However, her mother has called the clinic to report that it does not seem to work when her daughter is experiencing acute symptoms. What does the nurse think in response to the mother's concerns?

<p>Salmeterol is indicated for prevention of bronchospasms; it is not to be used for relief of acute symptoms. (B)</p> Signup and view all the answers

A patient is experiencing a severe anaphylactic reaction to an antibiotic. Which drug would be used to treat this condition?

<p>epinephrine (Adrenalin) (D)</p> Signup and view all the answers

Inhaled salmeterol is indicated for which condition?

<p>Asthma (D)</p> Signup and view all the answers

Adrenergic drugs that cause relaxation of the bronchi (i.e., bronchodilation) stimulate which receptors?

<p>ẞ₂-Adrenergic receptors (D)</p> Signup and view all the answers

When an older adult is taking an adrenergic drug, what must the nurse carefully monitor?

<p>Blood pressure and pulse rate (B)</p> Signup and view all the answers

Which are adrenergic receptor responses to stimulation? (Select all that apply.)

<p>Increased heart rate (A), Dilation of bronchioles (C), Dilated pupils (D), Decreased motility of intestinal smooth muscle (F), Contraction of the uterine muscle (G), Increased renin secretion (H)</p> Signup and view all the answers

Which drug is used to help establish the diagnosis of pheochromocytoma?

<p>phentolamine (Rogitine®) (A)</p> Signup and view all the answers

A patient is going home with a new prescription for the β-blocker atenolol (Tenormin®). What important information should the nurse tell the patient about this drug?

<p>Never abruptly stop taking this medication. (D)</p> Signup and view all the answers

A patient has been on a dopamine drip, and the nurse notices that the infusion has extravasated into the tissue of the forearm. After stopping the infusion, the nurse immediately injects phentolamine into the interstitial catheter. What is the effect of this action?

<p>It increases blood flow to the ischemic site by vasodilation and prevents permanent tissue damage. (A)</p> Signup and view all the answers

A 58-year-old male has had a myocardial infarction (MI). He has begun rehabilitation and is ready for discharge. When he is given a prescription for metoprolol (Lopressor®), he becomes upset and says, "I don't have high blood pressure! Why did my doctor give me this medicine?" What is the nurse's best explanation to the patient?

<p>Studies have shown that this medication greatly increases survival in post-MI patients. (A)</p> Signup and view all the answers

A patient has received a prescription for prazosin (Minipress) to reduce urinary obstruction due to benign prostatic hyperplasia (BPH). What important information about this medication should the nurse give this patient?

<p>Until a tolerance is built up, lightheadedness may occur when standing up after sitting or lying down. (A)</p> Signup and view all the answers

During an assessment, the nurse learns that her patient called to tell her that she had taken two double doses that morning because the headache just would not go away. The patient is now dizzy, nauseated, and very weak. What should the nurse do immediately?

<p>Empty the stomach by gastric lavage (C)</p> Signup and view all the answers

Which β-blocker is indicated for the treatment of heart failure?

<p>carvedilol (A)</p> Signup and view all the answers

The nurse is teaching a patient about self-monitoring while taking a β-blocker at home. The nurse should teach the patient to measure apical pulse daily for 1 minute. What does the nurse instruct the patient to do if the pulse rate decreases to less than 60 beats per minute?

<p>Contact the physician for instructions. (B)</p> Signup and view all the answers

A 49-year-old male patient is in the clinic for a follow-up visit 6 months after starting a β-blocker for treatment of hypertension. During this visit, his blood pressure is 169/98 mm Hg, and he eventually confesses that he stopped taking this medicine 2 months ago because of an "embarrassing problem." What problem with this medication most likely caused him to stop taking it?

<p>Erectile dysfunction (B)</p> Signup and view all the answers

Indicate the appropriate medication in the top list for each condition listed in the lower list.

<p>Migraine headaches = A B-blocker drug Benign prostatic hyperplasia = An A-blocker drug Glaucoma = A B-blocker drug</p> Signup and view all the answers

Flashcards

Adrenergic drugs

Mimics the sympathetic nervous system, also called sympathomimetic drugs.

Positive Inotropic Effect

Increased force of contraction.

Effects of Adrenergic Drugs

Bronchial dilation, peripheral constriction and decreased intestinal peristalsis.

Primary benefit of Adrenergic Agonist for shock?

Increase blood pressure

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Indication for epinephrine

Acute asthma attacks

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Medication to maintain blood pressure in organs of a child for donation

Dopamine hydrochloride

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Nurses immediate assessment of patient's symptoms

The patient may be experiencing worsening of a pre-existing cardiac disorder.

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Response to Salmeterol concerns

Salmeterol is indicated for prevention of bronchospasms; it is not to be used for relief of acute symptoms.

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Drug to treat anaphylactic reaction

Epinephrine (Adrenalin)

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Indication for Inhaled Salmeterol

Inhaled salmeterol is indicated for long-term maintenance treatment of asthma.

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Study Notes

  • Adrenergic drugs mimic sympathetic nervous system neurotransmitters and are also called sympathomimetic drugs.

Beta-1 Adrenergic Receptors

  • Increased force of contraction caused by the stimulation of beta-1 adrenergic receptors is known as a positive inotropic effect.

Adrenergic Drug Effects

  • Increased heart rate is expected with adrenergic drugs.
  • Adrenergic drugs do not cause bronchial constriction or increased intestinal peristalsis.

Adrenergic Agonists

  • Increased blood pressure is the primary intended effect when an adrenergic agonist is administered to a patient experiencing shock.
  • Adrenergic agonists should not replace volume restoration with IV fluids.
  • Increased urine output is a secondary benefit if cardiac output and kidney perfusion increase.
  • Treatment of anxiety is not an indication for adrenergics.

Epinephrine

  • Acute asthma attacks are an indication for epinephrine (Adrenalin).

Dopamine Hydrochloride

  • Dopamine hydrochloride maintains blood pressure in organs awaiting transplantation.

Dobutamine

  • Dobutamine increases cardiac output by increasing myocardial contractility and stroke volume in heart failure patients.
  • Dobutamine may cause myocardial infarction, especially in patients with pre-existing cardiac disorders.
  • If a patient experiences a rapid increase in heart rate and blood pressure while on dobutamine, the nurse must assess the patient's condition for a worsening cardiac disorder.

Salmeterol Xinafoate

  • Salmeterol is for prevention of bronchospasms, and is not intended for acute symptoms.
  • Salmeterol dosage is usually one puff twice daily, 12 hours apart, for maintenance effects in patients older than 12 years.

Anaphylaxis Treatment

  • Epinephrine is the drug of choice for anaphylaxis.

Salmeterol

  • Inhaled salmeterol is indicated for long-term maintenance treatment of asthma.

Bronchodilation

  • Beta-2 adrenergic receptors are stimulated by adrenergic drugs that cause bronchodilation.

Monitoring Adrenergic Drugs

  • Vital signs must be closely monitored because of the cardiovascular and cerebrovascular effects of adrenergic drugs.

Adrenergic Receptor Responses to Stimulation

  • Adrenergic receptor activation leads to effects, including dilation of bronchioles, dilated pupils, and increased heart rate.
  • Decreased motility of intestinal smooth muscle, contraction of the uterine muscle, and increased renin secretion are also characteristic.

Phentolamine

  • Phentolamine is used in the diagnosis of pheochromocytoma.

Atenolol

  • Abruptly stopping atenolol can cause rebound hypertension and chest pain.

Dopamine Extravasation

  • Phentolamine increases blood flow to the ischemic site by vasodilation and prevents permanent tissue damage when injected after a dopamine infusion extravasates.

Metoprolol

  • Metoprolol is often prescribed to post-MI patients due to its cardioprotective properties and increased survival rates.

Prazosin

  • Prazosin may cause orthostatic hypotension and lightheadedness until tolerance develops and should be taken at bedtime for the first few doses.
  • Patients need to maintain adequate fluid intake to prevent urinary tract infection and stay hydrated.

Alpha-Blocker Overdose

  • The patient's stomach should be emptied, usually by gastric lavage, in an acute oral alpha-blocker overdose.

Carvedilol

  • Carvedilol is indicated for the treatment of heart failure.

Beta-Blocker Self-Monitoring

  • Patients should contact their physician if their pulse rate decreases to less than 60 beats per minute while taking beta-blockers.

Beta-Blocker Side Effects

  • Erectile dysfunction is a potential adverse effect of beta-blockers.

Medication Indications

  • Beta-blockers treat migraine headaches.
  • Alpha-blockers treat benign prostatic hyperplasia.

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