10 Questions
Which of the following is an example of a non-selective α-receptor antagonist?
Phentolamine
What is the main pharmacologic effect of α-adrenoceptor antagonist drugs?
Vasodilation
Which of the following is NOT a main group of α-adrenoceptor antagonist drugs?
α3-selective antagonists
Which type of adrenergic antagonist may be reversible or irreversible in its interaction with α-receptors?
Non-selective α-receptor antagonists
Which of the following is an example of an α2-selective antagonist?
Yohimbine
Which effect is NOT associated with the blockade of α1-receptors by α-adrenoceptor antagonist drugs?
Reflex tachycardia
Which α-adrenoceptor antagonist drug causes irreversible blockade of long duration?
Phenoxybenzamine
What is the most significant effect of Phenoxybenzamine?
Attenuation of catecholamine-induced vasoconstriction
What is the main clinical use of Phentolamine?
Reversal of the cardiac effects of excessive catecholamines
Why is Phenoxybenzamine contraindicated in patients with decreased coronary perfusion?
It induces reflex tachycardia
Test your knowledge about adrenergic antagonist drugs that bind to adrenoceptors and prevent their activation by endogenous catecholamines. Learn about the classification of these drugs based on their affinities for α or β receptors.
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