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Adrenergic Antagonist Drugs Overview

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Questions and Answers

Which of the following is an example of a non-selective α-receptor antagonist?

Phentolamine (correct)

Terazosin

Prazosin

Yohimbine

What is the main pharmacologic effect of α-adrenoceptor antagonist drugs?

Increase in blood pressure

Vasodilation (correct)

Bronchoconstriction

Decrease in heart rate

Which of the following is NOT a main group of α-adrenoceptor antagonist drugs?

Non-selective α-receptor antagonists

α3-selective antagonists (correct)

Ergot derivatives

α1-selective antagonists

Which type of adrenergic antagonist may be reversible or irreversible in its interaction with α-receptors?

Non-selective α-receptor antagonists Signup and view all the answers

Which of the following is an example of an α2-selective antagonist?

Yohimbine Signup and view all the answers

Which effect is NOT associated with the blockade of α1-receptors by α-adrenoceptor antagonist drugs?

Reflex tachycardia Signup and view all the answers

Which α-adrenoceptor antagonist drug causes irreversible blockade of long duration?

Phenoxybenzamine Signup and view all the answers

What is the most significant effect of Phenoxybenzamine?

Attenuation of catecholamine-induced vasoconstriction Signup and view all the answers

What is the main clinical use of Phentolamine?

Reversal of the cardiac effects of excessive catecholamines Signup and view all the answers

Why is Phenoxybenzamine contraindicated in patients with decreased coronary perfusion?

It induces reflex tachycardia Signup and view all the answers