Adrenergic Agonists and Antagonists

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5 Questions

Which type of drugs block the action of neurotransmitters at the adrenergic receptors?

Sympatholytic drugs

Which neurotransmitter is primarily released by adrenergic neurons?

Norepinephrine

Which family of receptors are found in the sympathetic nervous system?

α receptors

Which adrenoceptor has a higher affinity for phenylephrine?

α1 receptor

What is the rank order of potency for α-adrenoceptors?

Norepinephrine > isoproterenol > epinephrine

Study Notes

Adrenergic Receptors and Neurotransmitters

  • Alpha blockers are a type of drug that block the action of neurotransmitters at adrenergic receptors.
  • Norepinephrine (noradrenaline) is the neurotransmitter primarily released by adrenergic neurons.

Adrenoceptors in the Sympathetic Nervous System

  • The sympathetic nervous system contains a family of receptors known as adrenoceptors.

Adrenoceptor Affinity and Potency

  • The α1 adrenoceptor has a higher affinity for phenylephrine.
  • The rank order of potency for α-adrenoceptors is: α1 > α2.

Test your knowledge on adrenergic receptors, drugs that affect them, and the actions, therapeutic uses, and adverse effects of adrenergic agonists and antagonists.

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