Adrenergic Agonists and Antagonists

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Questions and Answers

Which type of drugs block the action of neurotransmitters at the adrenergic receptors?

  • Adrenergic agonists
  • Sympatholytic drugs (correct)
  • Sympathomimetic drugs
  • Drugs interrupting the release of norepinephrine

Which neurotransmitter is primarily released by adrenergic neurons?

  • Dopamine
  • Norepinephrine (correct)
  • Serotonin
  • Acetylcholine

Which family of receptors are found in the sympathetic nervous system?

  • α receptors (correct)
  • β receptors
  • γ receptors
  • δ receptors

Which adrenoceptor has a higher affinity for phenylephrine?

<p>α1 receptor (D)</p> Signup and view all the answers

What is the rank order of potency for α-adrenoceptors?

<p>Norepinephrine &gt; isoproterenol &gt; epinephrine (A)</p> Signup and view all the answers

Flashcards

Sympatholytic drugs

Drugs that block the action of neurotransmitters at adrenergic receptors.

Norepinephrine

The primary neurotransmitter released by adrenergic neurons.

α receptors

A family of receptors found in the sympathetic nervous system.

α1 receptor

An adrenoceptor with a high affinity for phenylephrine.

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Potency of α-adrenoceptors

Rank order: Norepinephrine > Isoproterenol > Epinephrine.

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Study Notes

Adrenergic Receptors and Neurotransmitters

  • Alpha blockers are a type of drug that block the action of neurotransmitters at adrenergic receptors.
  • Norepinephrine (noradrenaline) is the neurotransmitter primarily released by adrenergic neurons.

Adrenoceptors in the Sympathetic Nervous System

  • The sympathetic nervous system contains a family of receptors known as adrenoceptors.

Adrenoceptor Affinity and Potency

  • The α1 adrenoceptor has a higher affinity for phenylephrine.
  • The rank order of potency for α-adrenoceptors is: α1 > α2.

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