Adrenergic Agonist Agents and Neurotransmitters
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Questions and Answers

What is the main characteristic of carvedilol?

  • Nonselective beta-blocker and alpha-1 blocker (correct)
  • Selective beta-2 blocker
  • Selective beta-blocker
  • Selective alpha-1 blocker

What is the neurotransmitter in the central and pre-ganglionic synapse in the sympathetic system?

  • Serotonin
  • Norepinephrine
  • Dopamine
  • Acetylcholine (correct)

What is the type of neurotransmitter involved in the sympathetic post-ganglionic synapse?

  • Adrenergic (correct)
  • Cholinergic
  • Serotonergic
  • Dopaminergic

What is the number of synapses in the sympathetic system?

<p>3 (A)</p> Signup and view all the answers

What is the type of action of the beta-blocking agent in the treatment of CHF?

<p>Beta-adrenergic antagonist (D)</p> Signup and view all the answers

What is the afferent pathway in the eye?

<p>Parasympathetic (C)</p> Signup and view all the answers

Which of the following beta-adrenergic blocking agents has intrinsic sympathomimetic activity (ISA)?

<p>Pindolol (C)</p> Signup and view all the answers

What is the primary mechanism of beta blockers in reducing blood pressure?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is aclinical use of beta blockers?

<p>Treatment of glaucoma (D)</p> Signup and view all the answers

What is the effect of beta blockers on the heart rate?

<p>Decrease heart rate (A)</p> Signup and view all the answers

Which of the following beta blockers is a hybrid antihypertensive drug with alpha and beta blocking CV actions?

<p>Labetalol (D)</p> Signup and view all the answers

What is the effect of beta blockers on the automaticity of the SA node?

<p>Decrease automaticity (A)</p> Signup and view all the answers

Which of the following beta blockers is used to treat thyrotoxicosis?

<p>Propranolol (A)</p> Signup and view all the answers

What is the primary mechanism of action of indirect adrenergic agonists, such as tyramine, cocaine, and amphetamines?

<p>They enhance the accumulation of norepinephrine by inhibiting COMT and MAO enzymes (A)</p> Signup and view all the answers

What is the primary therapeutic use of dopamine?

<p>Treatment of cardiogenic shock and acute heart failure (C)</p> Signup and view all the answers

Which of the following is a selective alpha-1 adrenergic receptor agonist?

<p>Phenylephrine (C)</p> Signup and view all the answers

What is the mechanism of action of fenoldopam, a selective D1 and A2 receptor agonist?

<p>It induces vasodilation through activation of D1 and A2 receptors (B)</p> Signup and view all the answers

What is the primary effect of alpha-2 adrenergic receptor activation in the pancreas?

<p>Decreased insulin release (C)</p> Signup and view all the answers

What is the primary mechanism of action of reserpine, an anti-hypertensive agent?

<p>It depletes the storage of norepinephrine from central and peripheral synapses (C)</p> Signup and view all the answers

Which of the following is a non-selective beta adrenergic receptor agonist?

<p>Isoproterenol (D)</p> Signup and view all the answers

What is the primary function of beta 2 receptors in the context of aqueous humor production?

<p>Increase secretion (A)</p> Signup and view all the answers

What is the response elicited by alpha 2 receptors in the context of pupil size?

<p>Miosis (D)</p> Signup and view all the answers

What is the primary source of endogenous epinephrine?

<p>Medulla of the adrenal gland (B)</p> Signup and view all the answers

What is the side effect of epinephrine observed in 20-30% of aphakic patients?

<p>Maculopathy (B)</p> Signup and view all the answers

What is the primary indication for 1% epinephrine?

<p>Treatment of POAG (D)</p> Signup and view all the answers

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